International Study on Sagliker Syndrome and Uglifying Human Face Appearence in Severe and Late Secondary Hyperparathyroidism in Chronic Kidney Disease Patients

Sagliker syndrome in patients with secondary hyperparathyroidism and chronic renal failure: Case report

“…Sagliker syndrome is assumed to result from insufficient treatment of sHPT in early stages of CRF. This syndrome can be observed in developing countries where people lack access to necessary medical treatment and do not receive timely treatment for renal insufficiency [4] . Our country, is an economically distressed, has the disadvantages that could lead to the appearance of SS.…”

Oral and maxillofacial manifestations of chronic kidney disease–mineral and bone disorder: a multicenter retrospective study

“…24,25 Clinically, patients affected by Sagliker syndrome exhibit secondary HPT, severe skull and jaw bone alterations (microscopically consistent with OF), short stature, malocclusion, teeth abnormalities, upward-bended fingertips, knee and scapula distortions, neuropsychiatric disorders, and hearing loss. 25,26 In our sample, 4 patients affected by OF/RO were later considered to have symptoms consistent with Sagliker syndrome, although…”

Cephalometric craniofacial features of patients with Sagliker syndrome: a primary analysis of our experience

“…SS is characterized by a severe uglifying facial appearance resulting from extremely severe maxillary, mandibular, and nasal deformities, and dental anomalies, as well as pathologically benign softtissue oral neoplasms (Figure 1). It also entails numerous other manifestations including short stature, irregularly scattered skull changes, class II maxillary and mandibular malocclusion, fingertip changes, knee and scapula deformity, hearing loss, and neuropsychiatric disorders (1)(2)(3).…”