International Cartilage Repair Society (ICRS) and Oswestry macroscopic cartilage evaluation scores validated for use in Autologous Chondrocyte Implantation (ACI) and microfracture

Abstract

The ICRS and OAS are reliable and relevant scores that are now both validated for macroscopic evaluation of cartilage repair as a research tool.

Radially oriented collagen scaffold with SDF-1 promotes osteochondral repair by facilitating cell homing

“…Samples from each group were examined and photographed for evaluation according to the International Cartilage Repair Society (ICRS) macroscopic assessment scale for cartilage repair [32]. After gross examination, samples were fixed in 4% formalin, decalcified in 4% ethylenediamine tetraacetic acid for 14 days and then embedded in paraffin and cut into 7 mm sections.…”

In vitro and in vivo studies on the degradation of high-purity Mg (99.99wt.%) screw with femoral intracondylar fractured rabbit model

“…Expose femoral condyle along the original cut. After the detection of periosteum, the femoral condyle was dissected and distal part of the femur was then photographed and evaluated according to the adjusted Oswestry Arthroscopy Score (OAS) macroscopic assessment [17] (Table 3). Three times of measurement were performed blindly, and the average value was calculated.…”

Adhesive barrier/directional controlled release for cartilage repair by endogenous progenitor cell recruitment

“…The distal femurs were dissected and scored according to the International Cartilage Repair Society (ICRS) Macroscopic score [14]. After fixation in 10% neutral formalin, the tissue was decalcified for a month with 14% EDTA, embedded in a frozen section compound (aqueous embedding medium within a mold) (Leica Microsystems, Wetzlar, Germany) and frozen in a metal pan over a bath of liquid nitrogen.…”