This study aimed to create Electronic Publication (E-Pub) Modules for Class XI students at MAN 1 Padang Panjang on the subject of Plant Tissue Structure and Function. This study used the 4-D development model, which stands for define, design, develop, and disseminate, in accordance with the research and development (R&D) methodology. The product was evaluated using e-module validation test sheets. Three professionals, including a biology lecturer from IAIN Batusangkar and two biology instructors from MAN 1 Padang Panjang, verified the e-module utilizing validation tools. The analysis included both quantitative and qualitative data analysis, considering ideas, critiques, and comments from the experts, and to assess the development of the e-module, quantitative data analysis from the validators' survey responses was used. The study's conclusions show that the Electronic Publication (E-Pub) Based E-Modules have a validity score of 80% and are aligned with the measured components. E-Modules that are based on Electronic Publication (E-Pub) was feasible to use to students.