Insulin-like growth factor binding Protein-1/alpha-fetoprotein versus placental alpha microglobulin-1 for diagnosis of premature fetal membranes rupture

Abdelazim, Ibrahim A.; Al-Sherbeeny, Mohammed M; Ibrahim, Mohamed; Fahmy, Alaa; Rabei, Noha Hamed; Khalifa, Ayman M.

doi:10.5530/ami.2016.1.15

Cited by 8 publications

(6 citation statements)

References 2 publications

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“…Only four recent studies (Ruanphoo and Phupong, Deckmyn et al , AbuFaza et al , and Abdelazim et al ) have been available to reveal the role of Amnioquick duo+ in diagnosing PROM and these recent studies did not compare the accuracy and response time of Amnioquick duo+ with that of PAMG‐1 tests. To the best of our knowledge, our current study is the largest study to date on Amnioquick duo+, and has remained the only study that has compared the diagnostic response time of Amnioquick duo+ and the PAMG‐1 test in women with symptoms, signs, or features suggestive of PROM.…”

Section: Discussionmentioning

confidence: 99%

Accuracy and response time of dual biomarker model of insulin‐like growth factor binding protein‐1/ alpha fetoprotein (Amnioquick duo+) in comparison to placental alpha‐microglobulin‐1 test in diagnosis of premature rupture of membranes

Eleje

Ezugwu

Eke

et al. 2017

J of Obstet and Gynaecol

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Section: Discussionmentioning

confidence: 99%

Accuracy and response time of dual biomarker model of insulin‐like growth factor binding protein‐1/ alpha fetoprotein (Amnioquick duo+) in comparison to placental alpha‐microglobulin‐1 test in diagnosis of premature rupture of membranes

Eleje

Ezugwu

Eke

et al. 2017

J of Obstet and Gynaecol

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“…Neonates with SUA have 15 times higher risk of chromosomal abnormalities and a significant proportion of infants with SUA may have isolated occult renal anomalies. [12345678910]…”

Section: Discussionmentioning

confidence: 99%

“…The PPROM excluded after speculum examination, nitrazine test, AmnioQuick Duo test and amniotic fluid index (AFI). [34567]…”

Section: Case Reportmentioning

confidence: 99%

Prenatal diagnosis of single umbilical artery complicated by intrauterine growth retardation and preterm labor: Case report

Abdelazim

Abu-Faza²,

Hamed

et al. 2019

J Family Med Prim Care

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Fetuses with single umbilical artery (SUA) at great risk of intrauterine growth retardation (IUGR), intrauterine fetal death (IUFD) and prematurity. A 24-years-old woman, 28 weeks’ gestation, presented to the Ahmadi hospital, Kuwait, with history of preterm premature rupture of fetal membranes (PPROM). After exclusion of the PPROM, the ultrasound scan of the studied woman showed; asymmetrical IUGR with SUA. The diagnosis of SUA confirmed by the color flow Doppler. She delivered spontaneously at 36 weeks+2, and a cut section in the umbilical cord done to confirm the diagnosis of SUA. The congenital and chromosomal abnormalities of the studied neonate excluded after normal pelvi-abdominal, brain ultrasound and normal karyotyping (46, xx); respectively. The prenatal diagnosed SUA in the studied cases associated with IUGR, preterm labor (PTL) and small for gestational age (SGA). SUA can be considered a marker of diagnosable congenital fetal malformation (CFM) and aneuploidy.

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“…213 AmnioQuick Duo+ works in 10 minutes with 94.1% sensitivity and 87.5% specificity, and ROM Plus uses a combination of monoclonal and polyclonal antibodies with 99% sensitivity and 91% specificity in 5 to 20 minutes. 208,214 Both tests are susceptible to false positives from blood contamination due to the AFP, and all women with hemorrhage were excluded from diagnostic analysis.…”

Section: Diagnostics For Maternal Healthmentioning

confidence: 99%

“…208,214 Both tests are susceptible to false positives from blood contamination due to the AFP, and all women with hemorrhage were excluded from diagnostic analysis. 213 The Lactate Pro test determines the amount of lactate in vaginal fluid using an electrochemical strip powered by a battery. 215 Results appear in one minute with 85% sensitivity and 91% specificity.…”

Section: Diagnostics For Maternal Healthmentioning

confidence: 99%

Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

et al. 2017

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Each day, approximately 830 women and 7,400 newborns die from complications during pregnancy and childbirth. Improving maternal and neonatal health will require bringing rapid diagnosis and treatment to the point of care in low-resource settings. However, to date there are few diagnostic tools available that can be used at the point of care to detect the leading causes of maternal and neonatal mortality in low-resource settings. Here we review both commercially available diagnostics and technologies that are currently in development to detect the leading causes of maternal and neonatal mortality, highlighting key gaps in development where innovative design could increase access to technology and enable rapid diagnosis at the bedside.

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Insulin-like growth factor binding Protein-1/alpha-fetoprotein versus placental alpha microglobulin-1 for diagnosis of premature fetal membranes rupture

Cited by 8 publications

References 2 publications

Accuracy and response time of dual biomarker model of insulin‐like growth factor binding protein‐1/ alpha fetoprotein (Amnioquick duo+) in comparison to placental alpha‐microglobulin‐1 test in diagnosis of premature rupture of membranes

Accuracy and response time of dual biomarker model of insulin‐like growth factor binding protein‐1/ alpha fetoprotein (Amnioquick duo+) in comparison to placental alpha‐microglobulin‐1 test in diagnosis of premature rupture of membranes

Prenatal diagnosis of single umbilical artery complicated by intrauterine growth retardation and preterm labor: Case report

Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

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