Prenatal diagnosis of single umbilical artery complicated by intrauterine growth retardation and preterm labor: Case report

Abdelazim, Ibrahim A.; Abu-Faza, Mohannad; Hamed, Mohamed E S; Karimova, Bakyt; Shikanova, Svetlana; Zhurabekova, Gulmira

doi:10.4103/jfmpc.jfmpc_394_19

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…DOI: 10.1159/000509646 esis has been associated with congenital fetal malformations and chromosomal anomalies [Catanzarite et al, 1995;Wiechec et al, 2016;Abdelazim et al, 2019]. Abdelazim et al [2019] claimed that single umbilical artery can be considered a marker of diagnosable congenital fetal malformation and aneuploidy. Cantanzarite et al…”

Section: Discussionmentioning

confidence: 99%

A Case of Ring Chromosome 18 with Single Umbilical Artery Detected During Prenatal Period

Eras

2020

Mol Syndromol

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Fetuses with a single umbilical artery have a risk of increased chromosomal anomalies and congenital malformations. Ring chromosomes are rare and the phenotypic and clinical characteristics of affected individuals show great variability depending on the quantity of the lost critical genes or gains during the formation of the ring or due to mitotic instability. Ring chromosome 18 [r(18)] is characterized by short stature, craniofacial dysmorphism, mental and motor retardation, autoimmune disorders, extremity anomalies, dermal lesions, structural heart malformations, and kidney abnormalities. In this study, the clinical findings of a female patient who had a single umbilical artery in the prenatal period and was diagnosed as de novo r(18) by molecular karyotype analysis were compared with those in the literature. A detailed ultrasonographic examination of the fetus with a single umbilical artery may enable the detection of additional anomalies and thus the early diagnosis of chromosomal anomalies may be possible with prenatal genetic analysis.

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Section: Discussionmentioning

confidence: 99%

A Case of Ring Chromosome 18 with Single Umbilical Artery Detected During Prenatal Period

Eras

2020

Mol Syndromol

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“…Intrauterine growth retardation is an intrauterine fetal growth less than the normal potential growth as per the fetal race and gender [ 23 ].…”

Section: Methodsmentioning

confidence: 99%

Maternal and fetal outcomes after bariatric surgeries

Farghali,

Alhadhoud,

AlObaidly

et al. 2023

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Introduction Obesity is the most common medical problem affecting reproductive-age women. To detect the prevalence of obesity, and bariatric surgeries (BSs) in reproductive-age women, and the impact of obesity vs. BSs on the subsequent pregnancy outcomes. Material and methods Obese-pregnant women, and women underwent BSs before the current pregnancy, with complete antenatal, and delivery records were included in the current study. Collected data were analyzed using MedCalc 20.106 to calculate the odd ratio (OR), and relative risk (RR) of adverse maternal, and fetal outcomes in relation to maternal obesity vs. BSs. Results Data of 14,474 pregnant women were collected during this study; 33.94% (4912/14474) of them were obese, and 3.8% (546/14474) of them had previous BSs before the current pregnancy. The obese group has significantly higher odds, and RR of gestational diabetes mellitus (GDM) [OR 1.9 ( p = 0.0001), and RR 1.79 ( p = 0.0001)], gestational hypertension [OR 1.7 ( p = 0.0002), and RR 1.6 ( p = 0.0003)], and preeclampsia (PE) [OR 1.7 ( p = 0.0001), and RR 1.6 ( p = 0.0001)] compared to BSs group. The obese group has also significantly higher odds, and RR of cesarean sections (CSs) [OR 1.3 ( p = 0.008), and RR 1.25 ( p = 0.01)], and large for gestational age [OR 1.39 ( p = 0.01), and RR 1.3 ( p = 0.02)] compared to BSs group. Conclusions About 33.94% of the reproductive-age women in Kuwait are obese, and 3.8% of them had previous BSs. Obese-pregnant women are at increased risks of GDM, gestational hypertension, PE, and CSs. Bariatric surgeries reduced the rates of GDM, gestational hypertension, PE, and CSs significantly.

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