Insomnia severity in chronic kidney disease patients with various therapies

Abstract

<jats:title>Abstract</jats:title><jats:p>The prevalence of insomnia is greater in end-stage renal disease. The aim of our study was to determine the frequency of insomnia and subclinical insomnia in patients with various dialysis therapy and kidney transplant recipients, in order to assess the severity of insomnia and examine whether there is a difference in severity among groups. In cross-sectional study, we evaluated 120 patients with terminal renal failure. Based on therapy, patients were divided into four groups: hemodiafiltration, standard bicarbonate dialysis, peritoneal dialysis and kidney transplant recipients. The severity of insomnia was evaluated through the use of the Insomnia Severity Index (ISI). Most patients who reported any kind of insomnia problems with ISI were on conventional dialysis (80%), followed by hemodiafiltration (76.7%) and peritoneal dialysis (63.3%). Transplant recipients had least difficulties with insomnia (46.7%). Insomnia Severity Index showed that insomnia in end-stage renal patients is not very severe. Most of the patients had “no clinically significant insomnia”. Our findings indicate that patients on hemodiafiltration and transplant recipients have a significantly lower score on Insomnia Severity Index. Patients with end-stage renal disease have high frequency insomnia problems. However, our study shows that insomnia in these patients is not severe. Insomnia is the most frequent and severest in patients on standard bicarbonate dialysis.</jats:p>

Elements of mental hygiene and diet as factor of control chronical renal disease

“…[20] Prema literaturi, mnoštvo faktora pokreće ili pogoršava već uspostavljenu anksioznost i/ili depresiju. Dokazano je i u istraživanjima koja su sprovedena u našoj zemlji da poremećaj sna, tj.higijene sna i odmora, [21] kao i sindriom nemirnih nogu [22] koji je jedan od posledica HBI, dovode do pogoršanja psihičkog statusa pacijenta. Broj pacijenata sa psihijatrijskim bolestima je mnogo veći od poznatog jer se pacijenti najčešće ne obraćaju za pomoć.…”

“…Prve studije o niskoproteinskim dijetama kod pacijenata sa uremijom kao posledicom HBI, dovele su do zaključka da je ishrana uz ograničen unos proteina bila efikasna u smanjenju simptoma " uremične toksičnosti " i da je čak ovom dijetom moguće produžiti život [21,32,33]. Danas je u skladu sa najnovijim FDA preporukama došlo je do promena u definiciji "odgovarajucég" unosa proteina koji je ranije bio 1-1,2 g / kg TT /na dan [34,35].…”

Influence of dialysis modality and membrane flux on insomnia severity in haemodialysis patients

“…But, we wondered if the dialysis modality and membrane permeability can have an influence on the frequency and severity of insomnia in haemodialysis patients. Little information is available about this …”