Insight into hydrogels

Abstract

The development and introduction of injectable biomaterials and the identification of methods through which materials may form in situ are currently the topics of interest in materials science, specifically in the field of biomaterials. Over the last few decades, hydrogels which refers to the swellable polymeric matrices have gained wide attention due to their excellent characteristics such as swelling in different media, pH and temperature sensitivity, and sensitivity to other stimuli. Nowadays, injectable hydrogels have widely been studied due to their excellent insitu gelation at body temperature. These injectable insitu gels serve as depot system which ensures the local and systemic drug and gene delivery. These insitu gels also protect the proteins and peptide drugs invivo from environmental effect. The current review is made to report latest extensive literature regarding hydrogels, their classification, synthesis methods, structure of hydrogel network, methods of crosslinking, environment-sensitive hydrogel system, drug loading, and release, hydrogels as biosensors and applications of hydrogels.

Ion Exchange Controlled Drug Release from Polymerized Ionic Liquids

“…By forming a depot system, the drug release is shifted from the stomach to the small intestine which not only is advantageous by protecting the particles, slabs, coatings, films, and bulks. [16] Different types like conductive, shape-memory, or environment-responsive hydrogels have been developed, studied, and characterized. Important examples are hydrogel-based drug delivery systems for different cancer therapies providing a localized sustained release of the chemotherapeutics.…”

pH‐sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition

“…[7][8][9][10][11][12] Therefore, such materials deserve the potential applications in site-specific drug delivery systems and now have been successfully applied in biomedical area. [13][14][15][16][17] However, due to the complex manufacturing processes and high economic costs, this technology can rarely be seen in the industrial fields, such as in concrete structure. In fact, the polymer that can respond to the environmental pH is promising to be a candidate carrier for rebar inhibitors releasing control and employing the drug delivery control systems in such field may bring huge economic benefits.…”

Features of Structure and Properties of pHEMA-gr-PVP Block Copolymers, Obtained in the Presence of Fe2+

“…In recent years, the synthesis and study of polymer hydrogel materials is one of the priority areas of polymer science and practice, which is actively developing [ 1 , 2 , 3 , 4 , 5 , 6 ].…”