BackgroundMalawi has one of the highest incidences of premature birth, and preterm newborns are twice likely to die compared to full-term newborns. Fathers’ involvement could help with the situation because it is associated with positive outcomes. However, there is limited literature on the factors that influence fathers’ involvement in the care of preterm newborns in Malawi.MethodsA phenomenological study was conducted at Balaka District Hospital guided by the components of the model proposed by Lamb on male involvement and the Theory of planned behaviour to explore factors that influenced fathers’ involvement in the care of preterm infants. The district was selected due to its high infant mortality rate, which is above the national average. Sixteen in-depth interviews were conducted with fathers of preterm infants purposively sampled in June 2021. Interviews were digitally recorded and transcribed verbatim. Data were analyzed using thematic analysis guided by the Theory of Planned Behaviour. ResultsSeveral factors influence fathers’ involvement. These are perceived difficulty with care activities and benefits of involvement, gender roles and socio-cultural beliefs, work and other family responsibilities, social support, baby’s physical appearance/nature and health status, feedback from the baby, multiple births, and hospital’s physical environment and provision of basic needs. These were reported as being barriers and facilitators to fathers’ involvement in the care of their hospitalized preterm newborns.ConclusionFathers’ involvement in the care of hospitalized preterm newborns can be improved by finding ways of resolving the barriers. This could be through education, awareness, and encouragement of the fathers and their communities.