Inhibitory effect of clove oil nanoemulsion on fumonisin isolated from maize kernels

Singh, Priyanka; Dasgupta, Nandita; Singh, Vineeta; Mishra, Narayan Chandra; Singh, Hemant; Purohit, Shiv Dutt; Srivastava, Nidhi; Ranjan, Shivendu; Yadav, Narayan Prasad; Mishra, Bhartendu Nath

doi:10.1016/j.lwt.2020.110237

Cited by 18 publications

(14 citation statements)

References 40 publications

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“…Hence, a carrier system is necessary to encapsulate curcumin, protect it from degradation, and maintain its antioxidant properties, which could increase its bioavailability and effectiveness. Therefore, curcumin has been encapsulated in synthetic and natural materials to form liposomes, nanoparticles, microspheres, hydrogels, scaffolds/scaffolds/matrices, and so on, for healing infectious full‐thickness/deep wounds 7,12,13,16,17 …”

Section: Introductionmentioning

confidence: 99%

“…Therefore, curcumin has been encapsulated in synthetic and natural materials to form liposomes, nanoparticles, microspheres, hydrogels, scaffolds/scaffolds/matrices, and so on, for healing infectious full-thickness/deep wounds. 7,12,13,16,17 In this study, to enhance the healing of the full-thickness/deep wound, we aim at developing a novel biomatrix by embedding curcumin in the decellularized goat small intestine submucosa (DG-SIS), which consists of various extracellular matrix (ECM) biomolecules (e.g., glycosaminoglycans [GAGs], proteoglycans, collagens, fibronectins, and laminins) that may trigger the cells to multiply faster, accelerating the healing of the full-thickness wound. 18 DG-SIS is basically an ECM obtained by the removal of cells from G-SIS.…”

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confidence: 99%

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Curcumin in decellularized goat small intestine submucosa for wound healing and skin tissue engineering

et al. 2021

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Biomaterials derived from extracellular matrices (ECMs) were extensively used for skin tissue engineering and wound healing. ECM is a complex network of biomolecules (e.g., proteins), which provide organizational support to cells for growth. Thus, ECM could be an ideal biomaterial for fabricating the scaffold. However, oxidative stress and biofilm formation at the wound site remains a major challenge that could be neutralized using herbal ingredients (e.g., curcumin). In this study, ECM was extracted from the biowaste of the goat abattoir by using decellularization. The goat small intestine submucosa (G‐SIS) is decellularized to obtain the decellularized G‐SIS (DG‐SIS) and curcumin (in different concentrations) was incorporated in the DG‐SIS to fabricate curcumin‐embedded DG‐SIS scaffolds. Changes brought by increasing the concentrations of the curcumin in DG‐SIS were observed in various properties, including free radical scavenging and antibacterial properties. Results depicted that the scaffolds are porous, biodegradable, biocompatible, antibacterial, and hydrophilic and showed sustained release of curcumin. Besides, it showed free radicals scavenging property. The porosity and hydrophilicity of the scaffolds were decreased with an increase in the curcumin content. However, biodegradability, free radical scavenging, biocompatibility, and antibacterial properties of the scaffolds increased with an increase in the curcumin content. The DG‐SIS scaffold containing 1 wt % of curcumin may be a potential biomaterial for wound‐healing and skin tissue engineering.

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Section: Introductionmentioning

confidence: 99%

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confidence: 99%

Curcumin in decellularized goat small intestine submucosa for wound healing and skin tissue engineering

et al. 2021

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“…In a recent investigation by Singh P. et al (2020) , it has been observed that clove oil nanoemulsion effectively reduced the growth of Fusarium proliferatum and secretion of fumonisin B 1 and B 2 in maize kernels during storage conditions. More importantly, nanoemulsion not only enabled controlled delivery of EO or antimicrobial compounds, but also facilitated incorporation into complex food systems.…”

Section: Application Of Nanoemulsionmentioning

confidence: 99%

Essential Oil Nanoemulsion as Eco-Friendly and Safe Preservative: Bioefficacy Against Microbial Food Deterioration and Toxin Secretion, Mode of Action, and Future Opportunities

et al. 2021

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Microbes are the biggest shareholder for the quantitative and qualitative deterioration of food commodities at different stages of production, transportation, and storage, along with the secretion of toxic secondary metabolites. Indiscriminate application of synthetic preservatives may develop resistance in microbial strains and associated complications in human health with broad-spectrum environmental non-sustainability. The application of essential oils (EOs) as a natural antimicrobial and their efficacy for the preservation of foods has been of present interest and growing consumer demand in the current generation. However, the loss in bioactivity of EOs from fluctuating environmental conditions is a major limitation during their practical application, which could be overcome by encapsulating them in a suitable biodegradable and biocompatible polymer matrix with enhancement to their efficacy and stability. Among different nanoencapsulated systems, nanoemulsions effectively contribute to the practical applications of EOs by expanding their dispersibility and foster their controlled delivery in food systems. In line with the above background, this review aims to present the practical application of nanoemulsions (a) by addressing their direct and indirect (EO nanoemulsion coating leading to active packaging) consistent support in a real food system, (b) biochemical actions related to antimicrobial mechanisms, (c) effectiveness of nanoemulsion as bio-nanosensor with large scale practical applicability, (d) critical evaluation of toxicity, safety, and regulatory issues, and (e) market demand of nanoemulsion in pharmaceuticals and nutraceuticals along with the current challenges and future opportunities.

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“…40 These are substances belonging to mycotoxins that pose a serious threat to the human body. 40 The produced nanoemulsion with a size in the range of 103 nm effectively inhibited the growth of Fusarium proliferatum (filamentous mushrooms). HPLC measurements confirm a significant reduction of the charge of fumonisins (compounds produced by fungi) B1 and B2 to the maximum level recommended by the European Union.…”

Section: Food and Function Reviewmentioning

confidence: 99%

Nanoparticle applications in food – a review

et al. 2023

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Inhibitory effect of clove oil nanoemulsion on fumonisin isolated from maize kernels

Cited by 18 publications

References 40 publications

Curcumin in decellularized goat small intestine submucosa for wound healing and skin tissue engineering

Curcumin in decellularized goat small intestine submucosa for wound healing and skin tissue engineering

Essential Oil Nanoemulsion as Eco-Friendly and Safe Preservative: Bioefficacy Against Microbial Food Deterioration and Toxin Secretion, Mode of Action, and Future Opportunities

Nanoparticle applications in food – a review

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