Inhibition of Propionibacterium acnes-induced mediators of inflammation by Indian herbs

Jain, Amita; Basal, Eati

doi:10.1078/094471103321648638

Cited by 112 publications

(78 citation statements)

References 9 publications

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“…It has been reported that a secreted peptidoglycan of P. acnes can stimulate the production of the proinflammatory cytokines such as interleukin-1 (IL-1), IL-8, and tumor necrosis factor-alpha (TNF-α) by human monocytic cell lines and freshly isolated peripheral blood mononuclear cells from acne patients (Chen et al, 2002;Jain and Basal, 2004).…”

mentioning

confidence: 99%

Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria

Kim

Lee

et al. 2008

J. Gen. Appl. Microbiol.

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mentioning

confidence: 99%

Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria

Kim

Lee

et al. 2008

J. Gen. Appl. Microbiol.

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“…The numerous bacterial biotas on the skin produce low molecular weight chemotactic factors that release ROS (Jain and Basal, 2003). Recently, it was reported that the most chronic medical conditions of acne are characterized by both oxidative stress and inflammation.…”

Section: Indonesian Medicinal Plants As Antioxidant Sourcesmentioning

confidence: 99%

Use of Indonesian Medicinal Plants Products Against Acne

Batubara

Mitsunaga

2013

RAS

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Indonesia contains a diverse range of cultures and plants. For a long time, Jamu, which is a traditional Indonesian medicine, had been used for beauty and human health in Indonesia. In this study, Indonesian medicinal plants used for skin care were examined, and the relevant information was update to incorporate anti-acne therapies. The anti-acne mechanisms included antibacterial activity against Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus, bacterial lipase inhibition, antioxidant, and anti-inflammatory activities. Most of the Indonesian medicinal plants used in skin care showed anti-acne activity that utilized et least 2 of these mechanisms. The compounds isolated from the Indonesian traditional medicinal plants related to the anti-acne activities are also discussed. In conclusion, more research on Indonesian medicinal plants is needed.

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“…It was found that R. cordifolia caused a statistically significant suppression of ROS from PMNL. Thus, R. cordifolia showed anti-inflammatory activity by suppressing the capacity of P. acnes-induced ROS and proinflammatory cytokines, the two important inflammatory mediators in acne pathogenesis (Jain and Basal, 2003).…”

Section: Pre-clinical Studiesmentioning

confidence: 99%

Rubia cordifolia: a review

Patil¹,

Mohan²,

Kasture³

et al. 2009

Oriental Pharmacy and Experimental Medicine

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SUMMARYMedicinal herbs are significant source of synthetic and herbal drugs. In the commercial market, medicinal herbs are used as raw drugs, extracts or tinctures. Isolated active constituents are used for applied research. For the last few decades, phytochemistry (study of plants) has been making rapid progress and herbal products are becoming popular. According to Ayurveda, the ancient healing system of India, the classical texts of Ayurveda, Charaka Samhita and Sushruta Samhita were written around 1000 B.C. The Ayurvedic Materia Medica includes 600 medicinal plants along with therapeutics. Herbs like turmeric, fenugreek, ginger, garlic and holy basil are integral part of Ayurvedic formulations. The formulations incorporate single herb or more than two herbs (poly-herbal formulations). Medicinal herb contains multitude of chemical compounds like alkaloids, glycosides, saponins, resins, oleoresins, sesquiterpene, lactones and oils (essential and fixed). Today there is growing interest in chemical composition of plant based medicines. Several bioactive constituents have been isolated and studied for pharmacological activity. R. cordifolia is an important medicinal plant commonly used in the traditional and Ayurvedic system of medicine for treatment of different ailments. This review illustrates its major constituents, pharmacological actions substantiating the claims made about this plant in the traditional system of medicine and its clinical applications.

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Inhibition of Propionibacterium acnes-induced mediators of inflammation by Indian herbs

Cited by 112 publications

References 9 publications

Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria

Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria

Use of Indonesian Medicinal Plants Products Against Acne

Rubia cordifolia: a review

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