Ingenane diterpenoids from Euphorbia esula

Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)

“…Samples from different locations (China, Hungary, and North America) contained different diterpenes (jatrophanes, ingenanes). [158][159][160][161][162][163][164][165][166] In the diterpene series obtained from the Hungarian collection, the aromatic acyl residues were missing and the alcohol core of the compounds was different from that isolated from North American and Chinese samples. As concerns the diterpene composition, E. esula displays many similarities with E. salicifolia.…”

Effects of diterpenes from latex of Euphorbia lactea and Euphorbia laurifolia on human immunodeficiency virus type 1 reactivation

“…Some species are important as medicinal and nutritional plants, whereas others are sources of oil and biofuels; nearly 43 species of plants from the Euphorbia genus are distributed in Colombia and many are used in traditional medicine (Murillo, 2004). Additionally, about 400 diterpenoids have been isolated from plants of the Euphorbia genus (Lu et al, 2008) with a wide spectrum of biological activities such as skin and eye irritants (Ahmed et al, 1999), apoptotic (Blanco-Molina et al, 2001), cytotoxic (Vigone et al, 2005) and cell proliferation induction (Touraine et al, 1977) properties. Non-tumor-promoter diterpenes such as prostratin (12-deoxyphorbol 13-acetate) have anti-HIV-1 activity (Gulakowski et al, 1997).…”

A Review on the Chemistry of Eremanthine: A Sesquiterpene Lactone with Relevant Biological Activity

“…[5.3.0]Decane. The bicyclo [5.3.0]decane (hydroazulene system) is a nucleus present in a great variety of natural products such as the guaiane and pseudoguaiane sesquiterpenoids [21] and the guaiane , ingenane [52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67], daphnane [68][69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85][86], and asebotoxin [87][88][89][90][91][92][93][94][95] diterpenoids ( Figure 5). Due to the chemical, biogenetical, and pharmacological interests that these classes of substances present, the literature reports a vast number of published works, with prominence for the reviews on sesquiterpenoids…”