Influência dos parâmetros funcionais respiratórios na qualidade de vida de pacientes com DPOC

Abstract

Objective: To determine the quality of life of COPD patients by using the Medical Outcomes 36-item Short-Form Survey (SF-36) and the Saint George's Respiratory Questionnaire (SGRQ), correlating the scores with respiratory function parameters. Methods: This was a cross-sectional study involving 42 COPD patients. We used the SGRQ (a specific questionnaire) and the SF-36 (a general questionnaire), together with their component summaries, in order to determine the quality of life of these patients. The functional profile was assessed by means of spirometry, arterial blood gas analysis and the six-minute walk test. Results: Of the 42 patients, 30 (71.4%) were male and 12 (28.6%) were female. The mean age of the patients was 65.4 ± 8.0 years. The mean physical component summary and mean mental component summary scores were 37.05 ± 11.19 and 45.61 ± 15.65, respectively. The physical component summary correlated significantly with FEV 1 in L/s (r = 0.38; p = 0.012). There was a correlation between the SGRQ total score and FEV 1 (r = −0.50; p < 0.01). The SGRQ activity domain showed negative correlations with all respiratory function parameters. The multiple regression analysis showed that only FEV 1 correlated significantly with the SGRQ total score, as well as with the activity domain score (r= −0.32; p = 0.04 and r = −0.34; p = 0.03, respectively). Conclusions: In COPD patients, a decline in FEV 1 is associated with poorer quality of life, as evaluated using the SGRQ. The objective of the present study was to determine how respiratory function parameters-as assessed by spirometry, arterial blood gas analysis and the six-minute walk test (6MWT)-correlate with the quality of life of COPD patients by using the SGRQ (a specific questionnaire), as well as the SF-36 (a general questionnaire) and its component summaries (PCS and MCS).

Influência das características sociodemográficas e clínicas e do nível de dependência na qualidade de vida de pacientes com DPOC em oxigenoterapia domiciliar prolongada

“…(23) In the present study, the oxygen flow rate at rest and the nocturnal oxygen flow rate were because pain is a symptom that is not specific to the clinical profile of COPD. (8)(9)(10)(11) Contrary to the literature, which shows a predominance of males among COPD patients in less developed countries, our study sample followed the trend seen in studies conducted in developed countries and reporting a similar prevalence of COPD in males and females, which can be explained by changes in smoking patterns. (2,12) In addition, no significant correlation was found between gender and the SF-36 domains, which is consistent with the findings of other studies.…”

“…(9) In other studies involving similar samples, major changes have also been found in those two domains, which indicates that patients with those characteristics have physical limitations that compromise the performance of ADL. (10,11) In the present study, the bodily pain domain, despite being impaired, had the highest mean score (61.2) of all eight SF-36 domains, probably All patients were on LTOT. The patients with mild or moderate COPD were hypoxemic and showed evidence of cor pulmonale, as defined by the GOLD criteria.…”

“…In a study conducted in England and involving COPD patients, FEV 1 was found to correlate with the physical functioning, role-physical, social functioning, and general health domains, whose r values ranged from 0.15 to 0.25 (p < 0.001 for all). (25) In two other studies, FEV 1 was found to correlate with the SF-36 physical component summary (r = 0.38; p = 0.012), (10) as well as with a visual analog scale that rates health status (r = 0.19; p < 0.05). (26) Anemia, in addition to being a predictor of mortality in COPD patients on LTOT, can contribute to increasing dyspnea and cause exercise limitation.…”

Pulmonary function, chronic respiratory symptoms, and health-related quality of life among adults in the United States – National Health and Nutrition Examination Survey 2007–2010

“…Although pulmonary function impairment has been found to be associated with poor HRQOL in some studies, most studies have been conducted among small, clinical populations and not the general population [9-12]. In addition, most research has not included data on respiratory symptoms, relying primarily on spirometric measures of disease severity [10]. Also, most studies have not evaluated the association between respiratory symptoms and HRQOL septely from pulmonary function; therefore they have not been able to assess whether poor HRQOL was attributable to impaired pulmonary function rather than respiratory symptoms.…”

Correlation between functional capacity and health-related quality of life in COPD: a case series

“…Pereira et al (26) conducted a study with COPD patients (2009) and found no correlation between the 6-MWT and the SF-36 PSS (physical summary scale) and MHSS (mental health summary scale). However, differently from our study and from other studies discussed previously, these authors have used the summary scales instead of the eight individual scales.…”