“…Locally prepared and commercially popular chewing tobacco products in India, like Pan masala and Guthkas, contains areca nut, tobacco, cardamon, lime and very often they are sweetened with unrefined sugar, sugar crystals, coconut or artificial sweeteners and flavors (32,33). The added flavor and sweeteners are used to promote tobacco use and neutralize its harsh taste (7,32,35). Chewing tobacco, typically used by placing a wad of tobacco between teeth and buccal mucosa, and is gently chewed or sucked over a period of several hours, is used over an extended period of each day (7,13,35).…”