Influence of seasonal variation on Thymus longicaulis C. Presl chemical composition and its antioxidant and anti-inflammatory properties

The relevance of pharmacognosy in pharmacological research on herbal medicinal products

“…2 illustrates the differences in the phytochemical profiles of T. longicaulis leaf extracts produced from material collected at 4 different seasons and the impact of this variation on bioactivity. While the antioxidant capacity was not strongly affected by seasonal variation, the October extract that was particularly rich in methylapigenin showed marked in vitro antiinflammatory activity, while the July extract exerted cytotoxic effects on colon and breast cancer cell lines comparable with or higher than those observed for the known anticancer drug vinblastine [65].…”

“…Not only the content of polyphenolic constituents but also the in vitro bioactivity of the respective extracts was found to be subject to seasonal variaton in Thymus longicaulis C. Presl. and Calamintha nepeta (L.) Savi [65,66]. Fig.…”

Anti-inflammatory, anticoagulant and antioxidant effects of aqueous extracts from Moroccan thyme varieties

“…These aromatic plants produce a large amount of secondary metabolites (e.g. phenol compounds) that are able to exert beneficial effects for human well-being [26]. Considering the involvement of free radicals in inflammation [27] and the relationship between inflammation and the coagulation systems [28] , the current study aimed at analyzing the aqueous extracts of three endemic medicinal plants (T. satureioides, T. zygis and T. atlanticus) for their antioxidant, anti-inflammatory and anticoagulant activities.…”

Inhibitory effects of wild dietary plants on lipid peroxidation and on the proliferation of human cancer cells

“…Anticarcinogenic effects of many plants derivatives, by inhibiting cancer cell proliferation in vitro, were assessed in many scientific reports (Galasso et al, 2014;Petiwala et al, 2014;Mastron et al, 2015).…”