Influence of polymer network parameters of tragacanth gum-based pH responsive hydrogels on drug delivery

Synthesis of nanohydrogels based on tragacanth gum biopolymer and investigation of swelling and drug delivery

“…It is well known that with immersion of the hydrogels in water, the molecules of water diffused inside the hydrogels and the interaction of water molecules with the functional ionic groups of the hydrogels results the electrostatic repulsion between charges on different polymeric chain. This increases the dimensional of the samples led to increase in swelling [18]. As shown in Fig.…”

Green Synthesis: Nanoparticles and Nanofibres Based on Tree Gums for Environmental Applications

“…GT consists of two fractions; tragacanthic acid or bassorin is insoluble in water, but has the capacity to swell and form a gel, and the other fraction is called tragacanthin and is water-soluble. Both fractions contain small amounts of proteinaceous material and methoxyl groups, the latter being present in higher amounts in the water-soluble fraction [94]. The water-swellable tragacanthic acid fraction has a high molecular weight and a rod-like molecular shape.…”

Chemically Modified Natural Polysaccharides to Form Gels

“…During this reaction, the initiator abstracts a hydrogen atom from tragacanth gum chain, and poly(acrylic acid) initiates from this point leading to a grafted polymer. Due to the presence of the plurality of -COOH units along the poly(acrylic acid) chain, the system displayed a reduced swelling and drug release at low pH (Singh and Sharma 2014).…”