Influence of low molecular weight compounds associated to cashew ( Anacardium occidentale L.) fiber on lipid metabolism, glycemia and insulinemia of normal mice

Abstract

The objective of this study was to evaluate the effect of cashew fiber wheter or not associated with low molecular weight compounds on lipid profile, abdominal adiposity, glycemia and insulinemia and serum concentration of ghrelin and leptin hormones from normal mice. We evaluated the cashew fiber in its integral form (IcF) and the cashew fiber after being submitted to the process of extraction of low molecular weight metabolites (cFSM). The two fibers were incorporated into the feed of male Swiss mice for 15 weeks. At the end of the treatment, blood glucose, total cholesterol and fractions, triglycerides, urea, AST, ALT, hormone levels of insulin, leptin and ghrelin were analyzed, as well as GSH and hepatic MDA. The consumption of cFSM diet promoted reduction of glycemia, insulin and ghrelin. Animals fed the IcF diet showed hyperlipidemia, hyperleptinemia and increased abdominal fat. In addition, no changes were observed in the lipid profile of the animals, in the abdominal adiposity and in the leptin hormone in the group that received cFSM diet. We conclude that the removal of small molecules is fundamental to use cashew fiber as a functional food with possible health benefits.

Comparison of Proximate and Phytonutrient Compositions of Cashew Nuts and Apples from Different Geographical Areas of Burkina Faso

“…In fact, dietary fiber helps reduce risk factors associated with the development of various chronic diseases, such as obesity, cardiovascular disease, and type 2 diabetes, by promoting the reduction of weight, blood sugar, and lipid profile [ 40 ]. Fibers are among the most used ingredients in functional foods, representing more than 50% of the total ingredients on the market [ 41 ]. They are also used as a food and pharmacological supplement [ 40 ].…”

Cashew bagasse (Anacardium occidentale L.) as a source of fiberantioxidant and its possible use in lipoinflammation models

“…After extraction of the juice by pressing, 25% of a residue called bagasse is generated with a high concentration of fiber, which varies from 41.53% ps , to 33% in fresh bagasse (Rodrígues et al, 2007). Various authors have reported the effect of the administration of cashew bagasse in murine models, such as the case of Carvalho et al (2017), who administered 10% of sonicated and lyophilized bagasse to a group of healthy rats, causing an increase in body weight and elevation of serum triglyceride and LDL cholesterol levels after 15 weeks. Later, Carvalho et al (2019) administered natural cashew fiber (IcF) and cashew fiber after undergoing a low molecular weight metabolite (cFSM) extraction process to obese male Swiss mice for 15 weeks.…”

CIERMMI Women in Science Biology, Chemistry and Life Sciences Handbook T-XIV

“…After extraction of the juice by pressing, 25% of a residue called bagasse is generated with a high concentration of fiber, which varies from 41.53% ps (Matias et al, 2005), to 33% in fresh bagasse (Rodrígues et al, 2007). Various authors have reported the effect of the administration of cashew bagasse in murine models, such as the case of Carvalho et al (2017), who administered 10% of sonicated and lyophilized bagasse to a group of healthy rats, causing an increase in body weight and elevation of serum triglyceride and LDL cholesterol levels after 15 weeks. Later, Carvalho et al (2019) administered natural cashew fiber (IcF) and cashew fiber after undergoing a low molecular weight metabolite (cFSM) extraction process to obese male Swiss mice for 15 weeks.…”