Objective: The development of a product aimed at the recreation sector such as toys for children can represent many obstacles due to the public to which it is addressed and the problems that come to reflect with the efficiency of the plastic material and how that can affect the product itself. Method: Our starting point in this project was to make research about products that were already made, we had to became familiar with the materials commonly used for the invention of toys, know its properties until we find the ideal material for our product which in the end it turned out to be the HDPE of SABIC. Then based of previous knowledge we wrote the functional analysis of the product to characterize the functions offered by our product to satisfy the needs of our users. Next, we capture the ideas in a pulse sketch to be able to later make an electronic sketch with the help of a SolidWorks to make the idea tangible and do the necessary changes to the problems that progressively presented themselves to us. In fact, the invention of the toy evolved as we went along, this was precisely the strongest barrier of the whole assignment. Furthermore, we decide based on our judgment and research that the best method to make our culture kit was through injection, because it benefits us in the aspects of time and cost of the process. Consequently, we had the task of carrying out mechanical resistance tests in the Mold Flow software to ensure that our design was practical. Contribution: Finally, we had to obtain the approximate cost of machinery in the production invested on our piece, which gave us a cost of about 4.938 €. And that helped us to obtain countable results from simulations, such as the cycle time.

This volume, Women in Science T-X-2021 contains 8 refereed chapters dealing with these issues, chosen from among the contributions, we gathered some researchers and graduate students from the 32 states of our country. We thank the reviewers for their feedback that contributed greatly in improving the book chapters for publication in these proceedings by reviewing the manuscripts that were submitted. As the first chapter, Gutiérrez, Mejía, Terán and Acuña, present Prototype of an electronic system for innovation in the Papillomavirus test registration process, as the second chapter, Arizmendi, De La Torre and Meza, will talk about Women as literary creation: a diachronic-representative journey, as third chapter, Arteaga, Alvarado, Castañeda and Torres, present Intellectual biography of Latin American academic women, as fourth chapter, Ramírez, Díaz and Figueroa, propose Flipped classroom a model for autonomous learning, as fifth chapter, Ponce, López and Méndez, as the sixth chapter, Otero, developed Educational innovation through techno-pedagogical tools in virtual education, as the seventh chapter, Juárez, Silveyra, Aguilar and Cuevas, will discuss Necessary pedagogical innovations: university internationalization initiatives and virtual environments in front of COVID-19, as the last chapter, Quitl, Nava And Jiménez, focus on Comparison of adaptation and family cohesion among adolescents with and without suicide risk in Tlaxcala.

As the first chapter, Terán, Cisneros and Gutiérrez present Knowledge of health personnel about HPV screening tests: a systematic review, as second chapter, González, Meraz, Chávez and González will discuss Health Risk Behaviors and Emotional State of Medical Students as third chapter, Aguilar, Morado, Villada and Tovar present Early trauma as conditioning of psychopathology in adult women, as fourth chapter, Torre, Therio, Carrillo and Mendoza propose Growth and development of the craniofacial region and the stomatognathic apparatus, as the fifth chapter, Villarreal, Enriquez, Hernández and Medina, perform Assessment of physical activity, sedentary behaviors and physical fitness in perimenopausal women, as the sixth chapter, Díaz, González, Uvalle and Mederos develop Pro-Inflammatory cytokines: Leptin and visfatin associated to obesity in young university students, as seventh chapter, Enríquez, Vieyra, Ramos and Trujillo, will discuss Presence of neuroglobin in the substantia nigra in a murine model of parkinson's disease: an immunohistochemical study, in eighth chapter, Martínez, Tavizon, Carlos and Mauricio present Prevalence of ectopic eruption and intercanine distance in children aged 6 to 12 years. Cycle 2019-2020, as the ninth chapter, Caceres, Zárate, Flores and Bustillos, performed Anxiety in medical students, during a COVID-19 pandemic and as the last chapter, González, Hernández, Martínez and González, focus on Overwiev of general plant toxicology uses and adverse effects.

In recent years, society has achieved a better quality of life; this has been possible thanks to scientific and technological advances. Among the advances that have allowed us to move forward is, without a doubt, the development of the vaccine against the SARS-CoV-2 virus. The method used for the synthesis of this vaccine was developed by Ugur Sahin and Öezlem Türeci, founders of BioNTech. Yes, behind the scientific development of greatest impact and relevance in recent years are a man and a woman. This scientific development was possible thanks to both of them, and here it is important to highlight the quality of women in science related to seeing issues from another perspective. Therefore, the union of their strengths and their differences made it possible to have a vaccine that makes it possible to return to life without confinement, without fear of going out, and with the possibility of enjoying it. Thus, the role of women in science is not only valuable, but fundamental to solve the problems that afflict us today. In this context, I can only thank and congratulate the women who today, thanks to their training, discipline and commitment, are giving us this wonderful work of science. I am sure that more challenges will come, but always counting on them, we will come out ahead. My most sincere appreciation and admiration.

This volume, Women in Science T-XIV-2021 contains 7 refereed chapters dealing with these issues, chosen from among the contributions, we gathered some researchers and graduate students from the 32 states of our country. We thank the reviewers for their feedback that contributed greatly in improving the book chapters for publication in these proceedings by reviewing the manuscripts that were submitted. As first chapter, Martínez, Bravo, Sánchez and Montoya present Effect of the consumption of Stevia rebaudiana Bertoni as a natural and artificial sweetener on fatigue and oxidative stress of skeletal muscle, as second chapter, Hernández, Ramírez, Chávez and Oliart, will talk about Cashew bagasse (Anacardium occidentale L. ) as a source of fiber-antioxidant and its possible use in lipoinflammation models as the third chapter, Marcos, Ramirez, Oliart, and Guadarrama present The relevance of the source of animal or vegetable proteins on the metabolic syndrome and its comorbidities, as the fourth chapter, Damián, Rivera, Lizárraga and Vázquez. propose Wanderings of a magic element: the biogeochemical cycle of manganese, as the fifth chapter, Sánchez, Paniagua, Temiche and Alexander, perform Methods of physical control of pathogenic microorganisms in hospital areas, as the sixth chapter, Paniagua, Sánchez, Corro and Alexander develop Use of power ultrasound, supercritical fluids and membrane technology to obtain and/or preserve biological products for clinical use, and as the last chapter, Estrada, Figueroa, Sierra and Aguilar, focus on Obtaining and characterization of the ethanolic extract of the leaves of the Tradescantia Spathacea SW.