Influence of jojoba meal supplementation on growth and organ function in rats

Cokelaere, Marnix; Buyse, Johan; Daenens, Paul; Decuypere, Eddy; Kühn, Eduard; Boven, Maurits Van

doi:10.1021/jf00033a017

Cited by 27 publications

(27 citation statements)

References 26 publications

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“…As shown in Table (9) serum T3 and T4 levels showed numerical significant (P<0.05) increase for T4 in group fed R1 as compared with the other group. These results coincide with those reported previously by Amouts et al (1993) in poultry and by Cokelaere et al (1993) and Flo et al (1998 and in rats. The same authors recorded that simmondsin reduces the body weight due to its effect on thyroid hormones and insulin.…”

Section: Itemsupporting

confidence: 93%

“…Total protein, albumin and globulin were non significantly increase (P>0.05) in lambs fed R4 ration than those fed R3 ,R1 and R2, this may induce reduction in feed intake and loss of essential amino acids and thus, decrease in the protein. Synthesis and these results coincide with the results reported previously by Verbiscar et al (1980), Cokelaere et al (1992), Cokelaere et al (1993), and Sobhy et al (2003). In the present study, the activity of ALT enzyme was significantly higher (P<0.05) in lambs fed R4 than those fed R1, R3 and R2.…”

Section: Itemsupporting

confidence: 93%

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Nutritional Evaluation of Treated Jojoba Meal by Aspergillus Oryzae as Sheep Feed

Abdou

2018

Egyptian Journal of Nutrition and Feeds

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he present study was to investigate the effect of feeding biologically treated jojoba meal(TJM) by Asperigullis oryzae (Fk-923) on digestibility coefficient, nutritive value, blood metabolic, and rumen characteristic of sheep. Twenty Barki male sheep were used in a randomized complete blocks designed (four groups of five sheep each) average body weight 36.42 +2.05 kg and aged 4-5 years old. The experiment aimed to study the feed evaluation of sheep feed on treated jojoba meal. The experimental concentrate rations were as follow:R1: Control treatment (yellow corn (40%), wheat bran (20%), cotton seed meal (30%), molasses (6%), salt (1.5%), limestone (2%), and (0.5%) mineral premix, R2: Yellow corn (40%), wheat bran (20%), cotton seed meal (20%), jojoba meal (10%), molasses (6%), salt (1.5%), limestone (2%) and (0.5%) mineral premix, R3: Yellow corn (40%), wheat bran (20%), cotton seed meal (10%), jojoba meal (20%), molasses (6%), salt (1.5%), limestone (2%) and (0.5%) mineral premix and R4: Yellow corn (40%), wheat bran (20%), jojoba meal (30%), molasses (6%), salt (1.5%), limestone (2%) and (0.5%) mineral premix. The results indicated that the high crude protein content in jojoba meal with fungus was associated with lower crud fiber content. It is noted that the treated jojoba recorded an improvement in CP, CF. higher than the untreated jojoba meal. Jojoba meal with fungus decreased the simmondsin contents from 5% in untreated jojoba meal to 0.17% JM treated. Chemical analyses of CP and EE in the R4 were found to be higher than those of R3, R2 and R1, while crude fiber, NDF, ADF contents recorded lower values in R4 than other rations. Results of digestibility trail showed that animals fed R1 and R3 recorded higher (P<0.05) DM, CP, OM, EE, NDF and ADF digestibility compared to other diets. The TDN g/kg BW and TDN % were higher in R3 compared to the ether diets. The DCP as g/h//d and DCP% of R1, R3 and R4 were significantly (p<0.05) higher than R2. The higher NI, FN and total excretion were recorded by R4 compared to other diets. Ruminal PH higher value was recorded in zero time and tended to decrease at 3hrs and 6hrs after feeding .Rumen ammonia-N concentration was increased at 3hrs and decrease at 6hrs after feeding. the Jojoba ration showed higher (P<0.01) TVFA , s production 3hrs after feeding ,but lower (P<0.01) at 6hrs after feeding in R2 and R3 verses R1 and R4. Starting from 2hrs to 24hrs of incubation the R3and R4 combinations showed higher gas produced volume than R2 and control. The highest potential gas production soluble (a) and insoluble (b) for treated Jojoba meal with fungi. Total protein, albumin and globulin were non-significantly increased (P>0.05) in lambs fed R4 ration than in those fed R3, R1 and R2. The activity of ALT and AST enzyme was significantly. Serum T3 and T4 levels showed numerical significant (P<0.05) increase for T4 in group fed R1 as compared with the other group. feeding sheep on R 3 and R 4 reduced the cost of one Kg DCP compared with lambs fed on R 2 and control ration. This 20...

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Section: Itemsupporting

confidence: 93%

Section: Itemsupporting

confidence: 93%

Nutritional Evaluation of Treated Jojoba Meal by Aspergillus Oryzae as Sheep Feed

Abdou

2018

Egyptian Journal of Nutrition and Feeds

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“…Indeed, vagotomy in rats reduced the effects of exogenously administered simmondsin and CCK [34]. Marnix et al [38] have worked with the same concentration of jojoba used in our study and the results showed that this concentration caused a reduction in the food intake and weight loss in the rats in 2 weeks. Boozer et Herron [39] proved that simmondsin produced a clear dose-response effect on this dietary intake as well as weight loss and that simmondsin at 0.15 and 0.25% significantly reduced these parameters without any undesirable effects.…”

Section: Discussionsupporting

confidence: 57%

Anorexic and metabolic effect of jojoba: potential treatment against metabolic syndrome and hepatic complications

Belhadj

Dal

Fakhreddine³

et al. 2020

Nutr Metab (Lond)

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Background: Evaluation of the action of various traditional plants to treat metabolic syndrome are strongly studied. In our study, we investigated the effect of the Tunisian jojoba seed on a metabolic syndrome induced in rat by the High Fat diet and High Fructose (HFHF) and its renal and hepatic complications. Methods: The rats were fed with HFHF or Normal Diet (ND) for a period of 8 weeks. After that, a switch from HFHF to ND or Normal Diet Jojoba (NDJ),(jojoba diet approach) or High Fat and High Fructose and Jojoba diet (HFHFJ) (nutraceutical approach) has been done. Metabolic disorder was evaluated by measuring the fasting body weight, glycemia and C-peptide and leptin. Oxidative stress parameters like ThioBarbituric Acid Reactive Substances (TBARS) and Total Antioxidant Capacity (TAOC) were analyzed in the plasma and renal and hepatic function were determined by the measure of creatinine and alanine transferase (ALT) respectively. Histological analysis was performed on the liver, kidney and pancreas. Results: HFHF diet exhibited characteristics of metabolic syndrome presented by insulin resistance, hyperinsulinemia, hyperleptinemia, fat mass with hepatic steatosis and renal disorder. HFHF diet was associated with oxidative stress (OS) presented by an increase in TBARS and a decrease in TAOC. Adding jojoba seeds to HFHF rat group diet induced a decrease in body weight, fat mass (58 and 41%), insulin resistance (59 and 56%), oxidative stress (60 and 41%), liver steatosis (from a score = 3 to a score = 0) and renal complications (25 and 42%). This effect was emphasized with diet approach. Conclusion: The results demonstrated the beneficial effect of jojoba against metabolic syndrome and oxidative stress, suggesting that jojoba could be used in the prevention and treatment of metabolic syndrome.

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“…All injections with vehicle or devazepide were given 15 min before food presentation. The simmondsin used, extracted and purified as previously described (Van Boven et al 1993), was HPLC pure. Experiment 2 In a second experiment, a group often rats was trained for 3 weeks to eat their daily ration in the 4 h between 1100 h and 1500 h, with a daily 20-h fasting period.…”

Section: Methodsmentioning

confidence: 99%

“…Because dilatation of the mesenteric vessels and the appear¬ ance of mesenteric hemolymph nodes were observed in jojobaor simmondsin-treated rats, it has been suggested that the cholecystokinin (CCK) system could be involved in the anorexic action of simmondsin (Cokelaere et al 1993). …”

Section: Introductionmentioning

confidence: 99%

Devazepide reverses the anorexic effect of simmondsin in the rat

Cokelaere¹,

Busselen²,

Flo³

et al. 1995

Journal of Endocrinology

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Simmondsin, a glycoside extracted from jojoba meal (Simmondsia chinensis), causes a reduction in food intake after oral administration. To investigate the mechanism by which simmondsin reduces food intake, fasted and free-feeding rats were given simmondsin-supplemented food and simultaneously injected with devazepide, a specific antagonist of peripheral-type cholecystokinin receptors (CCKA receptors). In free-feeding rats, supplementation of food with 0.5% simmondsin caused a reduction in food intake of +/- 40% in the period of 4 h following food presentation. Intraperitoneal injection of 100 micrograms devazepide/kg body weight prevented this effect. In rats fasted for 20 h, the food intake in the 30 min after presentation of food supplemented with 0.15% or 0.50% simmondsin was reduced in a dose-related manner; this was also inhibited by simultaneous application of devazepide. It is suggested that peripheral CCKA receptors are involved in the effect of simmondsin on food intake. However, a direct effect of simmondsin on CCKA receptors has been excluded, since simmondsin was unable to cause contraction of the guinea-pig gallbladder in vitro.

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Influence of jojoba meal supplementation on growth and organ function in rats

Cited by 27 publications

References 26 publications

Nutritional Evaluation of Treated Jojoba Meal by Aspergillus Oryzae as Sheep Feed

Nutritional Evaluation of Treated Jojoba Meal by Aspergillus Oryzae as Sheep Feed

Anorexic and metabolic effect of jojoba: potential treatment against metabolic syndrome and hepatic complications

Devazepide reverses the anorexic effect of simmondsin in the rat

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