Influence of Implant Surface Topography on Primary Stability in a Standardized Osteoporosis Rabbit Model Study

Abstract

Evaluating primary stability is important to predict the prognosis of dental implant treatment. Primary stability is decreased in a low bone density site such as osteoporosis. However, it is difficult to apply in small animal and the effect of the different implant surface topography for the primary stability at low bone density site has not yet fully been investigated. The purpose of the present study was to evaluate the influence of implant surface topography on primary stability in a standardized osteoporosis animal model. Six rabbits underwent ovariectomy and administrated glucocorticoid to induce an osteoporosis model. Sham-operations were performed in additional six rabbits. Implants with machined or oxidized-surfaces were inserted into the femur epiphyses and insertion torque (IT) and implant stability quotient (ISQ) were measured. In sham model, the IT and ISQ did not differ significantly between the both implant. However, the IT value of oxidized-surface implant was significantly higher than that of the machined implant in the osteoporosis model. Meanwhile, ISQ did not significantly differ between the machined and oxidized-surfaced implants. In conclusion, the IT of implants is higher with rough than with smooth surfaces but that there are no differences in ISQ value between different surfaces in a standardized osteoporosis bone reduced rabbit model.

FGF‐2 promotes initial osseointegration and enhances stability of implants with low primary stability

“…; Oue et al. ). ISQ value of the glucocorticoid‐induced osteoporotic animals was lower than normal at the installation in the distal epiphysis of the rabbit femur (Oue et al.…”

Intermittent administration of parathyroid hormone enhances primary stability of dental implants in a bone-reduced rabbit model

“…Furthermore, in terms of mechanical strength analysis, our previous study showed that the maximum mechanical bone strength in the bonereduced rabbit model was lower than that in a normal rabbit model. Therefore, the glucocorticoid-induced model showed a greater reduction of bone density and mechanical strength of femoral cortical bone (16). Intermittent PTH administration affects bone quality by promoting preosteoblastic proliferation and osteoblast bone formation.…”

“…Our previous study of primary stability demonstrated that the IT and ISQ values were significantly lower in the osteoporosis rabbit model than in the untreated rabbit model. Furthermore, a previous evaluation of tibial bone mechanical strength by the 3-point bending test indicated that bone strength in animals with osteoporosis was significantly lower than that in normal animals (16).…”

Osseointegration of zirconia and titanium implants in a rabbit tibiae model evaluated by microtomography, histomorphometry and fluorochrome labeling analyses

“…The screw‐type implant aids in the easy acquisition of primary stability. Moreover, implant surface topography is a key factor in achieving osseointegration . The most common modification of implant topography is surface roughness, which can be achieved by acid etching, sandblasting or oxidization .…”

“…Moreover, implant surface topography is a key factor in achieving osseointegration . The most common modification of implant topography is surface roughness, which can be achieved by acid etching, sandblasting or oxidization . Among the different surface‐treatment techniques, the use of a resorbable blasting medium (RBM) is a classic subtractive technique that is used for dental implant surfaces .…”