Influence of glucose homeostasis on maturation and ontogenesis of fetus

Hrabovski, Ivan; Milasnovic, Ljubomir; Grujić, Zorica; Grujić, Ilija

doi:10.2298/mpns1112552h

Cited by 1 publication

(2 citation statements)

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“…Both groups of diabetic mothers presented with a statistically significantly higher incidence of neonatal hypoglycemia compared to healthy controls without recorded hypoglycemia. Hrabovski et al 16 also established a higher incidence of hypoglycemia, hypocalcemia and hypomagnesemia in infants of diabetic mothers compared to healthy controls.…”

Section: Discussionmentioning

confidence: 94%

“…During labor and birth process, infants of mothers with diabetes are at increased risk for neonatal hypoglycemia, due to interrupted glucose supply and hyperinsulinism 2,16 . Perinatal stress is also associated with neonatal hypoglycemia, in part because of catecholamine and glycocorticoid-stimulated mobilization and depletion of glycogen stores.…”

Section: Discussionmentioning

confidence: 99%

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The impact of diabetes mellitus on the course and outcome of pregnancy during a 5-year follow-up

et al. 2014

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The results of our study show a higher incidence of perinatal fetal morbidity (hypoglycemia, jaundice, respiratory distress syndrome) in the patients with type 1, type 2 and gestation diabetes than in the healthy controls. Also, we found a higher incidence of cesarean section in the patients with type 1 diabetes than in those with type 2, gestation diabetes and healthy controls. Although delivery in the patients with type 1, type 2 and gestational diabetes was completed approximately one to two weeks earlier compared to the healthy controls there was no statistically significant difference in the incidence of preterm delivery (≤ 36th week of gestation) between the women with diabetes and healthy controls. Preterm delivery associated with poorer glycaemic control reflected through higher values of HbA1c in third trimester. Risks from adverse pregnancy outcomes may be reduced to minimum by adequate preconception counseling of diabetic patients and early diagnosis of diabetes in pregnancy, in order to achieve glycemic control during organogenesis and within pregnancy and through the teamwork of endocrinologists, gynecologists and pediatricians.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%