Influence of barium substitution on bioactivity, thermal and physico-mechanical properties of bioactive glass

Arepalli, Sampath Kumar; Tripathi, Himanshu; Vyas, Vikash Kumar; Jain, Shubham; Suman, Shyam Kumar; Pyare, Ram; Singh, Shailendra

doi:10.1016/j.msec.2015.01.049

Cited by 62 publications

(20 citation statements)

References 39 publications

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“…Immersion in simulated body fluid (SBF) [38,39,[41][42][43][44][45][46]49,52,55,59] Immersion in Dulbecco's Modified Eagle Medium (DMEM) [48] Immersion in tris buffer [58] None [40,47,50,51,53,54,56,57] …”

Section: Bioactivity Tests Related Articlesmentioning

confidence: 99%

“…Considering all the twenty-two studies, ten of them are investigating the direct influence of different compositions of glasses on mechanical properties [38,39,47,48,51,53,55,56,58,59]. Most of them are investigating the silicates system, only one [47] is studying a porous silicate BG mixed with hydroxyapatite (HA).…”

Section: Compositional Features Mechanical Properties and Applicationsmentioning

confidence: 99%

“…In contrast, the glass composition used is always well detailed even though the researches are still focused especially on silicate systems-just one article studied Calcium Phosphates [46] and no Borate glasses are investigated. Between the ten articles focusing only on bioactive glass composition; eight analysed the effect of different elements added to a silicate system [38,39,47,51,53,55,58,59] and two articles investigated the effect of synthesis methods [48,56].…”

Section: Compositional Features Mechanical Properties and Applicationsmentioning

confidence: 99%

“…The flexural strength increases by adding Barium, because it acts as a sintering additive accelerating the melting, giving more homogeneity in the glass and more rigidity. Ba 2+ ions possess a larger ionic radius than Silicon ions, and this substitution allows the formation of a denser network in the glass structure [55]. Nitrogen increases microhardness and elastic modulus similarly influencing the network structure; substuting the trivalent N 3− ions for the divalent O 2− ions affects the contraction of the network and therefore reduces the molar volume and increases the density.…”

Section: Compositional Features Mechanical Properties and Applicationsmentioning

confidence: 99%

“…The two tests are almost always coupled and this combination leads to a complete evaluation for in vitro cells testing. Direct references to ISO procedures are adopted by four articles [38,48,55,59] and specifically deal with the biological evaluation of medical devices referring to ISO 10993-4, ISO 10993-5 and ISO 10993-12. Proper methodologies for blood testing, cytotoxicity testing and samples preparation are detailed.…”

Section: Bioactivity and Biocompatibility Assessmentmentioning

confidence: 99%

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Mechanical characteristic and biological behaviour of implanted and restorative bioglasses used in medicine and dentistry: A systematic review

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Section: Bioactivity Tests Related Articlesmentioning

confidence: 99%

Section: Compositional Features Mechanical Properties and Applicationsmentioning

confidence: 99%

Section: Compositional Features Mechanical Properties and Applicationsmentioning

confidence: 99%

Section: Compositional Features Mechanical Properties and Applicationsmentioning

confidence: 99%

Section: Bioactivity and Biocompatibility Assessmentmentioning

confidence: 99%

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Mechanical characteristic and biological behaviour of implanted and restorative bioglasses used in medicine and dentistry: A systematic review

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Multiferroic Reinforced Bioactive Glass Composites for Bone Tissue Engineering Applications

et al. 2018

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Nowadays controlling cellular responses and function of biological molecules is becoming one of the prime areas of focus in biomedical field. In this investigation, an attempt is made to generate in situ charge in bioactive glass (BAG) by incorporating BiFeO3 (BF, a multiferroic material). It is hypothesized that BF in BAG can accelerate cellular activities for rapid tissue healing with externally applied magnetic field due to in situ polarization. BAG composites with different amounts of BF (2 to 15 wt%) are prepared using ball milling followed by pressing and sintering. The composites are characterized in terms of microstructures, constituent phases, magnetic, and electrical properties. Further, in vitro cytotoxicity studies are performed to evaluate the influence of in situ polarization by culturing mouse preosteoblast cells (MC3T3) on BAG‐BF composites under different external magnetic field treatments. These in vitro cell‐materials interaction studies demonstrate that magnetic field strengths of 200 or 350 mT exposed for 30 min/day can enhance cell viability and proliferation on these composites up to three times. Hence, the authors expect that this investigation will enable further developments to extend the application of multiferroics in bone tissue engineering.

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Superparamagnetic Manganese Ferrite and Strontium Bioactive Glass Nanocomposites: Enhanced Biocompatibility and Antimicrobial Properties for Hyperthermia Application

et al. 2020

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Herein, the strontium bioactive glass with ferrite composites is studied for the application of biocompatibility and magnetic hyperthermia. The bioactive glass SrBG (46.1SiO2–21.9CaO–24.4Na2O–2.6P2O5–5SrO) prepared by the melt quench technique at 1400 °C and manganese ferrite (MnFe2O4) prepared by the modified microwave reflux oven are mixed together and sintered at 400 °C for 6 h for making composites. The in vitro bioactivity of these composites is observed by immersing in simulated body fluid (SBF). The growth of the precipitated hydroxyapatite phase observed after SBF treatment is confirmed by the X‐ray diffractometer (XRD), Fourier transform infrared (FTIR) spectrometer, and scanning electron microscope (SEM) results. The in vitro cell viability assessment of these composites with MG‐63 cell lines indicates that the composites are biocompatible in nature. Furthermore, these composites show the antibacterial effect on the E. coli and S. Aureus bacteria cells. The room temperature superparamagnetic behavior accompanied by the heating ability in these composites proves their potential role for hyperthermia applications.

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Influence of barium substitution on bioactivity, thermal and physico-mechanical properties of bioactive glass

Cited by 62 publications

References 39 publications

Mechanical characteristic and biological behaviour of implanted and restorative bioglasses used in medicine and dentistry: A systematic review

Mechanical characteristic and biological behaviour of implanted and restorative bioglasses used in medicine and dentistry: A systematic review

Multiferroic Reinforced Bioactive Glass Composites for Bone Tissue Engineering Applications

Superparamagnetic Manganese Ferrite and Strontium Bioactive Glass Nanocomposites: Enhanced Biocompatibility and Antimicrobial Properties for Hyperthermia Application

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