Inflammatory myofibroblastic tumor of the thigh without bone involvement: a case report

Abstract

Inflammatory myofibroblastic tumors are rare, and those located in the extremities without bone involvement are even rarer. We present the case of a 61-year-old Chinese male patient with an inflammatory myofibroblastic tumor of the right thigh. It was excised and a histopathologic examination revealed an inflammatory myofibroblastic tumor. This case is presented by virtue of its rare location.

Inflammatory myofibroblastic tumor arising from soft tissues of extremities harboring a novel CLIP2‐ALK fusion

“…IMT occurs in any anatomical part of the body. However, it rarely occurs in the soft tissues of the extremities, with no more than 20 cases reported, among which the thigh is the most common place, [2][3][4][5] followed by hand, 3,6 foot, 3 articular fossa, 7 and arm. 8 The age of IMT arising from the soft tissue of the extremities is widely distributed, ranging from 6 months to 61 years old.…”

Inflammatory Myofibroblastic Tumor of the Thigh: Presentation of a Rare Case and Review of the Literature

“…Patients with IMTs of the extremities have no systemic symptoms; anemia, fever, or weight loss, and laboratory abnormalities are uncommon [ 13 ]. However our patient had high levels of CRP and ESR.…”

“…The MR imaging features of IMT of the thigh are nonspecific on T1 and T2 weighted images. The IMT of the thigh [ 13 ] is reported to preferably create a slow growing mass located at the medial aspect of the thigh. In our case, there was a slow-growing mass in the intermuscular interval between adductors and vastus medialis and intermedius.…”

“…Previous reports have shown that there is a moderate to intense enhancement of the lesion with the use of contrast substance; whereas in our case there was only mild enhancement best seen in delayed images, probably due to the presence of abundant fibrous tissue around the lesion. Han and Lin have also noted that the degree of enhancement is associated with the relative cellularity and the amount of fibrous tissue of the myofibroblastic tumor [ 13 , 36 ]. Delayed and mild enhancement after administration of gadolinium is usually seen in lesions with excessive fibrous component such as desmoids and nodular fasciitis [ 13 , 36 ].…”

Diagnosis of EBV-Associated Inflammatory Pseudotumor in the Spleen: A Case Report

“…За длительный период существования данной «собирательной» нозологии были описаны наблюдения с вовлечением практически всех органов и тканей, чаще -с поражением ткани легкого и орбиты. В части наблюдений была установлена связь с местным воспалительным процессом, обусловленным предшествующей травмой (в т. ч. хирургической), аутоиммунным процессом, а также с опухолевым процессом по типу паранеопластической реакции [12][13][14][15][16][17][18][19][20][21][22].…”