Infections and Acute Leukemia in Children with Down Syndrome

Mejı́a-Aranguré, Juan Manuel; Pérez-Saldivar, María Luisa; Flores-Lujano, Janet; Méndez, Carolina Bekker; Pinto-Cardoso, Sandra; Duarte-Rodríguez, David Aldebarán; Fajardo-Gutiérrez, Arturo

doi:10.5772/18533

Cited by 4 publications

(1 citation statement)

References 107 publications

(127 reference statements)

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“…11 In this understanding, the consumption of these products with high concentration of pesticides can cause diseases such as cancer, kidney diseases, stomach, skin and eye diseases irritations and problems related to the central nervous system. 35 Given this scenario, it is evident that it is not only farmers in their activities that are exposed to pesticides, but the entire population due to factors such as contamination of natural resources and food. 28 With regard to the handling of pesticide packaging, the practice of improper reuse or disposal has become common among farmers.…”

Section: ]" (F4)mentioning

confidence: 99%

Implicações do uso de agrotóxicos:Percepções de familiares de crianças portadoras de neoplasia Implications of pesticide use: perceptions of families of children with cancer

Camponogara

Rodrigues

Dias

et al. 2017

R. pesq. cuid. fundam. online

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Objetivo: Conhecer as percepções de familiares de crianças portadoras de neoplasia atuantes como trabalhadores rurais acerca do processo de adoecimento e implicações do uso de agrotóxicos. Método: os dados foram coletados por meio de entrevista dirigida orientada por um formulário sociodemográfico e entrevista semi-estruturada, durante os meses de outubro de 2014 a janeiro de 2015. Os resultados transcritos foram analisados com base no referencial proposto para análise temática. Resultados: dos resultados emergiram duas categorias temáticas intituladas Percepções de familiares frente ao processo de adoecimento da criança e Percepções de familiares frente ao uso de agrotóxicos. Conclusão: acredita-se que a inserção da discussão sobre a problemática dos agrotóxicos na atividade rural possibilita novos olhares, visando a minimizar a crise ambiental, o processo de adoecimento e ampliar o entendimento do processo de saúde-doença como resultante, também, da integração do ser humano com o meio ambiente.

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Section: ]" (F4)mentioning

confidence: 99%

Implicações do uso de agrotóxicos:Percepções de familiares de crianças portadoras de neoplasia Implications of pesticide use: perceptions of families of children with cancer

Camponogara

Rodrigues

Dias

et al. 2017

R. pesq. cuid. fundam. online

View full text Add to dashboard Cite

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Model for the Origin of Acute Leukemias in Children: Interaction of Three Factors—Susceptibility, Exposure, and Window of Vulnerability

Mejı́a-Aranguré

2016

Etiology of Acute Leukemias in Children

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Molecular epidemiology of acute leukemia in children: causal model, interaction of three factors—susceptibility, environmental exposure and vulnerability period

Mejı́a-Aranguré

2016

Boletín Médico del Hospital Infantil de México

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Acute leukemias have a huge morphological, cytogenetic and molecular heterogeneity and genetic polymorphisms associated with susceptibility. Every leukemia presents causal factors associated with the development of the disease. Particularly, when three factors are present, they result in the development of acute leukemia. These phenomena are susceptibility, environmental exposure and a period that, for this model, has been called the period of vulnerability. This framework shows how the concepts of molecular epidemiology have established a reference from which it is more feasible to identify the environmental factors associated with the development of leukemia in children. Subsequently, the arguments show that only susceptible children are likely to develop leukemia once exposed to an environmental factor. For additional exposure, if the child is not susceptible to leukemia, the disease does not develop. In addition, this exposure should occur during a time window when hematopoietic cells and their environment are more vulnerable to such interaction, causing the development of leukemia. This model seeks to predict the time when the leukemia develops and attempts to give a context in which the causality of childhood leukemia should be studied. This information can influence and reduce the risk of a child developing leukemia.

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Infections and Acute Leukemia in Children with Down Syndrome

Cited by 4 publications

References 107 publications

Implicações do uso de agrotóxicos:Percepções de familiares de crianças portadoras de neoplasia Implications of pesticide use: perceptions of families of children with cancer

Implicações do uso de agrotóxicos:Percepções de familiares de crianças portadoras de neoplasia Implications of pesticide use: perceptions of families of children with cancer

Model for the Origin of Acute Leukemias in Children: Interaction of Three Factors—Susceptibility, Exposure, and Window of Vulnerability

Molecular epidemiology of acute leukemia in children: causal model, interaction of three factors—susceptibility, environmental exposure and vulnerability period

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