Infection of Japanese quail with Toxocara canis larvae and establishment of patent infection in pups

Pahari, T.K.; Sasmal, N. K.

doi:10.1016/0304-4017(90)90140-7

Cited by 11 publications

(10 citation statements)

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“…The establishment of patent infections in worm-free pups has been reported following the feeding of migratory T. canis larvae from different abnormal hosts (Japanese quail (Pahari & Sasmal, 1990a, b) and piglets (Acharya et al , 2002)), but no such studies on the establishment of patent infections have been reported previously by feeding infected droppings of cockroaches to worm-free pups. The infection rate of pups with adult T. canis also varied with the dose of infected faeces fed to these pups.…”

Section: Discussionmentioning

confidence: 99%

“…Bulk samples of embryonated eggs suspended in water were developed using the method described by Pahari & Sasmal (1990a). Ten T. canis -infected pups, 5–7 weeks old, were treated with albendazole for collection of adult T. canis .…”

Section: Methodsmentioning

confidence: 99%

“…Five faecal samples from each group were examined and a mean count taken (table 1). Eggs and larvae were identified after Nichols (1956) and Sprent (1955) and percent inoculum was calculated following the formula of Pahari & Sasmal (1990a).…”

Section: Methodsmentioning

confidence: 99%

“…The zoonotic significance of Toxocara canis larvae is of prime interest considering its strong tendency to cause ‘visceral larva migrans’ (VLM) in abnormal hosts, including humans, which act as paratenic hosts of T. canis . Toxocara canis larvae persist for months or years in a wide range of mammalian laboratory hosts (Pahari & Sasmal, 1990a) and it is presumed that they are transferred from animal to animal through paratenism in nature (Sprent, 1954; Pahari & Sasmal, 1990b). With regard to the role of invertebrates, Sprent (1956), Okoshi & Usui (1968) and Pahari & Sasmal (1991) reported successful infections of earthworms with T. cati and T. canis and the establishment of patent infections in the definitive host.…”

Section: Introductionmentioning

confidence: 99%

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Experimental infection of the cockroachPeriplaneta americanawithToxocara canisand the establishment of patent infections in pups

2008

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The possible role of the cockroach Periplaneta americana in the transmission of Toxocara canis eggs and larvae via faeces and tissue migration was studied. Cockroaches fed with 3 x 105 and 5 x 105 embryonated eggs were found to harbour viable eggs and larvae from days 1 to 5 post-infection (DPI). At necropsy on 5 DPI, eggs and larvae were also recovered from the rectal contents but not from the tissues of cockroaches. In addition patent infections were established in pups fed on infected faeces of cockroaches, with eggs first appearing in the faeces of pups at 38 DPI. Adult worms of T. canis were also recovered at necropsy. Therefore the importance of cockroaches as good mechanical disseminators of ascarid eggs, especially T. canis, is discussed.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Experimental infection of the cockroachPeriplaneta americanawithToxocara canisand the establishment of patent infections in pups

2008

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“…Puppies in the 10 d group were fed albendazole after the experiment, according to veterinary guidance. The liver was shredded to recover larvae by the modified Baermann funnel method for 12 h at 37 °C with 1% mycillin [16]. Fecal eggs of 36 d group dogs were daily examined from 30 to 36 dpi to determine the status of T. canis infection.…”

Section: Methodsmentioning

confidence: 99%

Serum metabolomic alterations in Beagle dogs experimentally infected with Toxocara canis

et al. 2019

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Background Toxocara canis, a globally distributed roundworm, can cause debilitating disease in dogs and humans; however, little is known about the metabolomic response of the hosts to T. canis infection. There is an increasing need to understand the metabolic mechanisms underlying the pathogenesis of T. canis infection in dogs. Here, we examined the metabolomic changes in Beagle dogsʼ serum following T. canis infection using LC-MS/MS. Results The metabolic profiles of Beagle dogsʼ serum were determined at 12 h, 24 h, 10 d and 36 d after oral infection with 300 infectious T. canis eggs by LC-MS/MS. We tested whether the T. canis-associated differentially abundant metabolites could distinguish the serum of infected dogs from controls, as measured by the area under the receiver operating characteristic (ROC) curve (AUC). The differentially expressed metabolites were further evaluated by principal components analysis and pathway enrichment analysis. A total of 5756 and 5299 ions were detected in ESI+ and ESI− mode, respectively. ROC curve analysis revealed nine and five metabolite markers, at 12 hpi and 24 hpi to 36 dpi, respectively, with potential diagnostic value for toxocariasis. The levels of taurocholate, estradiol, prostaglandins and leukotriene were significantly changed. Primary bile acid biosynthesis pathway, steroid hormone biosynthesis pathway and biosynthesis of unsaturated fatty acids pathway were significantly altered by T. canis infection. Conclusions These findings show that T. canis infection can induce several changes in the dog serum metabolome and that the metabolic signature associated with T. canis infection in dogs has potential for toxocariasis diagnosis.

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Parasites of Dogs

Bowman

Baker

2007

Flynn's Parasites of Laboratory Animals

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Infection of Japanese quail with Toxocara canis larvae and establishment of patent infection in pups

Cited by 11 publications

References 11 publications

Experimental infection of the cockroachPeriplaneta americanawithToxocara canisand the establishment of patent infections in pups

Experimental infection of the cockroachPeriplaneta americanawithToxocara canisand the establishment of patent infections in pups

Serum metabolomic alterations in Beagle dogs experimentally infected with Toxocara canis

Parasites of Dogs

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