Infantile mammary duct ectasia: A cause of bloody nipple discharge

Stringel, Gustavo; Perelman, Alvin; Jimenez, Carmencita

doi:10.1016/s0022-3468(86)80383-9

Cited by 49 publications

(56 citation statements)

References 12 publications

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“…3,5 However, mammary duct ectasia appears to be the most common cause for bloody nipple discharge among all cases that underwent histological verification. 1,7,8,9 The pathology was defined as dilatation of the mammary duct with periductal fibrosis and inflammation, as described in our case. 13 The sanguinous or serosanguinous nipple discharge can be attributed to the papillary growth seen in some areas of the ectatic duct epithelium.…”

Section: 35-9mentioning

confidence: 87%

“…Despite limited clinical experience, the extreme rarity of malignant tumors in this age group and its self-limiting nature should reassure parents during the few months needed for cure. 3,5,6,9 The fact that 17 cases of juvenile secretory carcinoma of the breast have presented as asymptomatic swellings and none have given rise to nipple discharge, may support this recommendation. 15 Excisional biopsy should, as a general rule, be avoided, particularly in girls.…”

Section: 35-9mentioning

confidence: 99%

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Bloody Nipple Discharge in a 4-Year Old Child

et al. 2003

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Breast enlargement is considered a physiologic event in male and female neonates. However, it is rarely encountered in infancy and is deemed unusual in young children beyond the first year of life.1,2 Breast enlargement along with bloody nipple discharge, first reported in 1983 3 appears to be even more uncommon in children. We report a case of a 4-year-old boy with a 2-week history of left breast enlargement with serosanguinous nipple discharge and ipsilateral palpable axillary lymph nodes. Case ReportA 4-year-old boy was referred to the pediatric surgical service after the mother presented her child with a history of bloody nipple discharge of one week duration to the emergency room physician. The mother noted blood stains initially on the boy's underwear and later saw blood coming out of the left nipple. There was no history of breast enlargement, pain or fever. Trauma and drug ingestion were denied. Physical examination revealed a healthy child with normal findings except for an ovoid mass measuring 2.5 x 1.5 centimeters above the left nipple. It was mobile, not attached to underlying structures or skin, firm, and not tender or hot. There was no erythema. Slight pressure on the mass instigated bloody discharge from the nipple (Figure 1). The left axilla revealed two enlarged lymph nodes, one measuring 0.5 centimeter, the other 2.0 centimeters in diameter. The right breast and axilla were normal. The testes were of normal size, configuration and consistency. The complete blood count, prothrombin time and partial thromboplastin time were normal. The breast mass, including the small nipple, were excised. Both axillary lymph nodes were removed as well.The frozen section proved to be a benign lesion. The paraffin section demonstrated many dilated ducts containing granular eosinophilic material and red blood cells. In some, there were many macrophages containing foamy granular material within the lumen and pronounced periductal fibrosis with a moderate chronic inflammatory reaction in the adjacent wall (Figure 2). An occasional dilated duct proved that focal ulceration was present. A section from the left nipple showed a few dilated ducts with similar microscopic changes. A section from the axillary lymph nodes illustrated sinus histiocytosis.

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Section: 35-9mentioning

confidence: 87%

Section: 35-9mentioning

confidence: 99%

Bloody Nipple Discharge in a 4-Year Old Child

et al. 2003

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“…"Pseudotumour cerebri" (benign intracranial hypertension) has been repeatedly observed [1,2,[4][5][6]8]. Papilloedema in these children probably reflected optic neuritis, perineuritis or papillitis.…”

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confidence: 98%

“…Bloody nipple discharge is very rare in infancy and childhood [1,3,5,7,8]. Myers and Kaplan [7] described a 4-month-old white girl and a 13-month-old white boy with breast masses measuring 1-1.5 cm in diameter and bleeding from the nipple.…”

mentioning

confidence: 99%

“…In both infants the masses were excised and cystic ductal hyperplasia with intracystic granulation tissue was found histologically. In one of two cases reported by Stringel et al [8], a boy, a fight subcutaneous mastectomy was performed for bloody nipple secretion of 3 months duration and a left subcutaneous mastectomy for bleeding from the left nipple a year later. Pathological diagnosis was mammary duct ectasia.…”

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Neuro-ophthalmological manifestations of tick-borne borreliosis: a case report

1993

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In Europe Lyme disease is caused by the spirochete Borrelia burgdorferi sensu lato. It presents with a variety of clinical manifestations including heart disease and problems of the nervous system, skin and joints. Lyme carditis occurs in 4-10% of infected humans and is characterized by a plethora of cardiovascular syndromes such as arrhythmia, myocarditis, and pericarditis among others. This article is a case report of a serologically positive (B. burgdorferi s.l.) dog, in which the antibody dynamics correlated with clinical, electrocardiographic, and echocardiographic findings of heart disease resembling human Lyme-induced dilated cardiomyopathy (DCM). List of abbreviations AF = atrial fibrillation; ALP = alkaline phosphatise; ANA test = antinuclear antibody test; AV = atrioventricular; BID = twice daily; CBC = complete blood count; CDCD-VFU = Clinic of Dog and Cat Diseases, University of Veterinary and Pharmaceutical Sciences, Brno; DCM = dilated cardiomyopathy; DNA = deoxyribonucleic acid; ECG = electrocardiography; IgG = Immunoglobulin G; IgM = Immunoglobulin M; PCR = polymerase chain reaction ; SF = shortening fraction; SID = once daily; TBE = tick-borne encephalitis; TID = three times daily; VHS = vertebral scale size

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