Increasing photostability and water-solubility of carotenoids: Synthesis and characterization of β-carotene–humic acid complexes

Martini, Silvia; D’Addario, Claudia; Bonechi, Claudia; Leone, Gemma; Tognazzi, Antonio; Consumi, Marco; Magnani, Agnese; Rossi, Claudio

doi:10.1016/j.jphotobiol.2010.08.008

Cited by 35 publications

(16 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Figure A and B show the effect of Z ‐isomer content of β‐carotene and astaxanthin on the DSC analysis. The melting points of (all‐ E )‐β‐carotene and (all‐ E )‐astaxanthin were 175.5 and 213.0 °C, which was in good agreement with previous studies . Increasing Z ‐isomer content of β‐carotene and astaxanthin, the melting points reduced.…”

Section: Resultssupporting

confidence: 91%

Enhanced solubility and reduced crystallinity of carotenoids, β-carotene and astaxanthin, by Z -isomerization

Honda

Kodama

Kageyama

et al. 2018

Eur. J. Lipid Sci. Technol.

View full text Add to dashboard Cite

The impact of the Z‐isomer content of carotenoids, β‐carotene and astaxanthin, on their solubility in organic solvents and crystallinity is investigated. Carotenoid samples containing different Z‐isomer contents are prepared from the high‐purity all‐E‐isomers by the thermal isomerization and filtering technique: β‐carotene, 27.4% and 89.8% Z‐isomer content; astaxanthin, 34.5% and 63.2% Z‐isomer content. As the Z‐isomer content of the carotenoids increases, their relative solubility markedly improves, e.g., the solubility in ethanol of β‐carotene containing 89.8% Z‐isomer is ≈250 times higher than that of the all‐E‐isomer. Moreover, differential scanning calorimetry (DSC), powder X‐ray diffraction (XRD), and scanning electron microscopy (SEM) analyses clearly indicate that the (all‐E)‐carotenoids are present in the crystal state, while the Z‐isomers are present in an amorphous state. A number of studies have reported that the Z‐isomerization of carotenoids induced changes in bioavailability and antioxidant activity. This may be due to the change in physicochemical properties such as solubility and crystallinity by Z‐isomerization. In addition, these changes are important information for improving carotenoid processing. Practical Applications: Carotenoids in plants occur predominantly in the all‐E‐configuration, whereas the Z‐isomers are present in the human body in considerable quantity. Since (all‐E)‐carotenoids have low solubility in solvents and high crystallinity, efficiencies of those processing such as solvent extraction, micronization, and emulsification are low. However, this study experimentally reveals that solubilities of carotenoids, β‐carotene and astaxanthin, are significantly improved and crystallinities of them are reduced by Z‐isomerization. These fundamental data should contribute to improvement of carotenoids processing efficiency. The effect of the Z‐isomer content of carotenoids, β‐carotene and astaxanthin, on their solubility in organic solvents and crystallinity is investigated. Increasing the Z‐isomer contents of the carotenoids, those solubility improved and those crystallinity reduced.

show abstract

Section: Resultssupporting

confidence: 91%

Enhanced solubility and reduced crystallinity of carotenoids, β-carotene and astaxanthin, by Z -isomerization

Honda

Kodama

Kageyama

et al. 2018

Eur. J. Lipid Sci. Technol.

View full text Add to dashboard Cite

show abstract

“…Similar changing patterns of EE% and LA have been observed for the complexation between SPI and curcumin . The EE% (84–96%) is basically comparable to that observed for β‐ carotene encapsulated in β ‐lactoglobulin aggregates produced under high pressure (89–99%) and aggregated caseins (73–83%), but considerably higher than that for β‐ carotene encapsulated in ferritin nanocages (about 32%), in complexes with humic acid (<56%) . The EE% is also higher than that for β‐ carotene encapsulated by other techniques, e.g.…”

Section: Resultssupporting

confidence: 74%

Soy protein isolate as a nanocarrier for enhanced water dispersibility, stability and bioaccessibility of β‐carotene

2016

View full text Add to dashboard Cite

show abstract

“…Humic acid is a principal component of humic substances, which are the chief organic constituents of soil, peat, coal, many upload streams, dystrophic lakes, and ocean water [2]. Humic acid is able to complex trace metals, especially the intermediate metals such as Mg 2 þ , Ca 2 þ , Fe 2 þ , and Fe 3 þ at its carboxylic and phenolic groups, i.e.…”

Section: Introductionmentioning

confidence: 99%

Structural analysis and binding domain of albumin complexes with natural dietary supplement humic acid

Ding¹,

Diao²,

Yang³

et al. 2011

Journal of Luminescence

View full text Add to dashboard Cite

Increasing photostability and water-solubility of carotenoids: Synthesis and characterization of β-carotene–humic acid complexes

Cited by 35 publications

References 39 publications

Enhanced solubility and reduced crystallinity of carotenoids, β-carotene and astaxanthin, by Z -isomerization

Enhanced solubility and reduced crystallinity of carotenoids, β-carotene and astaxanthin, by Z -isomerization

Soy protein isolate as a nanocarrier for enhanced water dispersibility, stability and bioaccessibility of β‐carotene

Structural analysis and binding domain of albumin complexes with natural dietary supplement humic acid

Contact Info

Product

Resources

About