Increased risk of bacterial endocarditis in inflammatory bowel disease

Cardiobacterium hominis endocarditis presenting as acute embolic stroke: A case report and review of the literature

“…We could not rule out his Crohn's disease as a risk factor for C. hominis endocarditis, because inflammatory bowel disease is a known risk factor for infective endocarditis. 29 Cardiobacterium hominis can also be found among gastrointestinal-tract flora, and a translocation of this bacterium from the gastrointestinal tract into the bloodstream could have occurred during unknown previous active inflammatory bowel disease in our patient. The patient's Achilles tendonitis might be a musculoskeletal manifestation of endocarditis.…”

Possible activation of an intramyocardial inflammatory process (Staphylococcus aureus) after treatment with infliximab in a boy with Crohn disease

“…Concerns have been raised about the safety of the drug because of its immunomodulating potential [14]. Patients with Crohn disease do carry additional risks as they are more susceptible to bacterial infections possibly due to their disturbed mucosal barrier and to concomitant immunosuppressive therapy [6,18]. In addition, Crohn disease itself may lead to vasculitic changes of the aorta [5,10,15], which might have further favoured the development of the intramyocardial abscess in our patient.…”

Burkholderia ginsengisolibacteraemia: emergence of a novel pathogen

“…In the setting of inflammatory bowel disease, bacteraemia may have multiple aetiologies and, in this case, several questions remain regarding the extent of infection 4 5. We speculate that exposure occurred through dietary consumption of organic vegetables, both raw and cooked and that the patient's compromised gastrointestinal mucosa facilitated bacterial translocation.…”