Increased Epicardial Fat Tissue Is a Marker of Subclinic Atherosclerosis in Ankylosing Spondylitis

Üstün, Nilgün; Kurt, Mustafa; Atci, Nesrin; Yagiz, Erman; Güler, Hayal; Turhanoğlu, Ayşe Dicle

doi:10.5606/archrheumatol.2014.4606

Cited by 6 publications

(2 citation statements)

References 29 publications

(39 reference statements)

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“…In studies in which body composition in AS was evaluated, changes within fat and muscle mass compared with normal controls were identified [ 35 ]. Another study reported that epicardial fat thickness was significantly increased in patients with AS compared with healthy controls [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

The effects of preobesity to quality of life, disease activity and functional status in patients with ankylosing spondylitis

Toy

Özbağ

Altay

2017

North Clin Istanbul

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OBJECTIVE:This study was an investigation of effects of pre-obesity on clinical characteristics and quality of life in patients with ankylosing spondylitis (AS).METHODS:Total of 28 AS patients and 30 age- and sex-matched healthy controls were included in the study. Patients and controls with any systemic inflammatory disease and/or cognitive and mental problems were excluded. Disease activity and functional capacity were measured using the Bath Ankylosing Spondylitis Disease Activity Index and Bath Ankylosing Spondylitis Functional Index. For quality of life assessment, 36-Item Short Form Health Survey was used in both groups, and AS group also responded to Ankylosing Spondylitis Quality of Life questionnaire.RESULTS:There was no significant difference in sociodemographic characteristics between AS patients and healthy controls (p>0.05). Mean quality of life scores were significantly lower in the pre-obese AS patients compared with controls (p<0.05). Functional capacity was positively and significantly associated with body mass index (BMI) (p=0.024) and disease activity was significantly associated with female gender (p=0.011).CONCLUSION:Increased BMI in patients with AS is factor that affects quality of life, disease activity, and functional capacity. Multidisciplinary rehabilitation programs will support improved quality of life for pre-obese patients with AS.

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Section: Discussionmentioning

confidence: 99%

The effects of preobesity to quality of life, disease activity and functional status in patients with ankylosing spondylitis

Toy

Özbağ

Altay

2017

North Clin Istanbul

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“…Abnormal increased activity has been shown in AS patients both in our study and previous studies. [29][30][31][32] It is predicted that these patients may have high risk for the development of AF. Though there is still no clear evidence, we believe that increased incidence of AF in AS patients may be related to chronic inflammation and increased myocardial fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Atrial Conduction Times, Epicardial Fat Thickness and Carotid Intima-Media Thickness in Patients With Ankylosing Spondylitis

et al. 2016

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Objectives: This study aims to determine the relationship between atrial electromechanical delay (EMD), carotid intima-media thickness (CIMT), and epicardial fat thickness (EFT) in ankylosing spondylitis (AS), which has a complicated inflammatory nature. Patients and methods:The study population included 42 consecutive patients with AS (28 males, 14 females; mean age 39.3±8.5 years; range 22 to 60 years) and 40 healthy subjects as controls (24 males, 16 females; mean age 37.2±8.7 years; range 22 to 60 years) (p>0.05). All patients underwent a standard tissue Doppler echocardiography to assess the left ventricular diastolic dysfunction, atrial EMD, CIMT, and EFT. All values were compared between the groups. Results: Interatrial (29.5±5.8 ms vs. 17.9±5.3 ms) left and right intraatrial EMD (18.2±4.6 ms and 11.7±3.5 ms vs. 11.9±3.2 ms and 7.1±3.2 ms, respectively) intervals were longer in AS patients than in healthy controls (all p<0.001). Left and right CIMT (0.50±0.11 mm and 0.44±0.06 mm vs. 0.51±0.11 mm and 0.43±0.04 mm, respectively) and EFT (0.73±0.15 cm and 0.63±0.07 cm) values were higher in AS patients than in healthy controls (all p<0.01). Conclusion: To our best knowledge, this is the first report evaluating the atrial EMD, CIMT, and EFT values together in AS patients. As indicators of cardiovascular involvement, all parameters were higher in AS patients.

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Increased epicardial adipose tissue thickness correlates with endothelial dysfunction in spondyloarthritis

et al. 2022

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Increased Epicardial Fat Tissue Is a Marker of Subclinic Atherosclerosis in Ankylosing Spondylitis

Cited by 6 publications

References 29 publications

The effects of preobesity to quality of life, disease activity and functional status in patients with ankylosing spondylitis

The effects of preobesity to quality of life, disease activity and functional status in patients with ankylosing spondylitis

Evaluation of Atrial Conduction Times, Epicardial Fat Thickness and Carotid Intima-Media Thickness in Patients With Ankylosing Spondylitis

Increased epicardial adipose tissue thickness correlates with endothelial dysfunction in spondyloarthritis

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