Incorporation of phenylpropanes into xylerythrin-type pigments in Peniophora sanguinea

Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides

“…In search of a representative compound to biochemically investigate homobasidiomycete natural product assembly we embarked on terphenylquinone pigments, for multiple reasons, e.g., they are produced under laboratory conditions by a number of cultivable species following different lifestyles (saprobic, symbiotic) and from various evolutionary clades within the fungal tree of life, they are assembled along a short and easy to delineate biosynthetic pathway and represent the skeleton structure for a variety of pigments. Feeding experiments established Ltyrosine or L-phenylalanine as building blocks for their biosynthesis (Read et al, 1962;von Massow, 1977;Liu, 2006). These amino acids are then deaminated into their corresponding a-keto acids followed by subsequent condensation into the substituted quinones (Fig.…”

Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544

“…The biosynthesis of the p -terphenyls has been studied since the 1960s [ 15 – 16 ]. Stable-isotope labeling experiments confirmed that ʟ-tyrosine or ʟ-phenylalanine are involved in the biosynthesis of p -terphenyl as metabolic origin.…”