Pigments of Fungi (Macromycetes)

Abstract

For Abstract see ChemInform Abstract in Full Text.

Sarcodonins and Sarcoviolins, Bioactive Polyhydroxy‐p‐terphenyl Pyrazinediol Dioxide Conjugates from Fruiting Bodies of the Basidiomycete Sarcodon leucopus

“…It is worth noting here that previously reported terphenyl metabolites having a para-quinone core, like the flavomentins AϪD from Paxillus atrotomentosus and P. panuoides, are orange pigments, while ortho-quinones, like the spiromentins AϪD [18] from P. atrotomentosus, or the hydroxylated phlebiarubrone derivatives from Phlebia strigosozonata, are violet pigments. [19] The λ max values in the UV-Vis spectrum of the pigment are very close to those of spiromentins AϪD and phlebiarubrone derivatives. [19] All these data strongly suggest that the structures of the constituents in the mixture of epimeric ortho-quinones are related to sarcodonins and episarcodonins, namely sarcoviolin α (10) and episarcoviolin α (11).…”

“…[19] The λ max values in the UV-Vis spectrum of the pigment are very close to those of spiromentins AϪD and phlebiarubrone derivatives. [19] All these data strongly suggest that the structures of the constituents in the mixture of epimeric ortho-quinones are related to sarcodonins and episarcodonins, namely sarcoviolin α (10) and episarcoviolin α (11). As further confirmation, the mixture of 10 and 11 was subjected to reductive acetylation with Zn/Ac 2 O, according to a standard procedure for fungal terphenylquinones.…”

Synthesis, Characterization, and Biological Evaluation of Some New Functionalized Terphenyl Derivatives

“…Terphenyl is a common structural motif found in various natural products, largely isolated from microbes and mushrooms [1]. In recent years, it has been reported that some terphenyls exhibit considerable biological activities, for example, potent anticoagulants, immunosuppressants, antithrombotic, neuroprotective, specific 5-lipoxygenase inhibitory, and cytotoxic activities [2].…”

(2E)-3-[4-(1H-Benzimidazol-2-ylmethoxy)-3-methoxyphenyl]-1-(4,4''-difluoro-5'-methoxy-1,1':3',1''-terphenyl-4'-yl)prop-2-en-1-one

“…Terphenyl is a common structural motif found in various natural products, largely isolated from microbes and mushrooms [1]. In recent years, it has been reported that some terphenyls exhibit significant biological activities, e.g., potent anticoagulant, immunosuppressants, antithrombotic, neuroprotective, specific 5-lipoxygenase inhibitory and cytotoxic activities [2].…”