Incorporation of Ca ions into anodic oxide coatings on the Ti-13Nb-13Zr alloy by plasma electrolytic oxidation

Michalska, Joanna; Sowa, Maciej; Piotrowska, Magdalena; Widziolek, Magdalena; Tylko, Grzegorz; Dercz, Grzegorz; Socha, Robert P.; Osyczka, Anna M.; Simka, Wojciech

doi:10.1016/j.msec.2019.109957

Cited by 18 publications

(10 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Whereas, Santos-Coquillat et al [99] deposited calcium, phosphorus, and silicon or fluorine on magnesium alloy using PEO to improve osteoblast growth, collagen secretion, and ECM mineralization. In turn, Michalska et al [100] modified the surface of the Ti-13Nb-13Zr alloy by electropolishing and PEO technique. They proved that the PEO coatings (containing calcium ions) on the Ti-13Nb-13Zr alloy significantly improved the cytocompatibility of biomaterial by promoting adhesion, proliferation, and osteogenic differentiation of human BMDSCs.…”

Section: Peekmentioning

confidence: 99%

Osteoconductive and Osteoinductive Surface Modifications of Biomaterials for Bone Regeneration: A Concise Review

Kazimierczak

Przekora

2020

Coatings

View full text Add to dashboard Cite

The main aim of bone tissue engineering is to fabricate highly biocompatible, osteoconductive and/or osteoinductive biomaterials for tissue regeneration. Bone implants should support bone growth at the implantation site via promotion of osteoblast adhesion, proliferation, and formation of bone extracellular matrix. Moreover, a very desired feature of biomaterials for clinical applications is their osteoinductivity, which means the ability of the material to induce osteogenic differentiation of mesenchymal stem cells toward bone-building cells (osteoblasts). Nevertheless, the development of completely biocompatible biomaterials with appropriate physicochemical and mechanical properties poses a great challenge for the researchers. Thus, the current trend in the engineering of biomaterials focuses on the surface modifications to improve biological properties of bone implants. This review presents the most recent findings concerning surface modifications of biomaterials to improve their osteoconductivity and osteoinductivity. The article describes two types of surface modifications: (1) Additive and (2) subtractive, indicating biological effects of the resultant surfaces in vitro and/or in vivo. The review article summarizes known additive modifications, such as plasma treatment, magnetron sputtering, and preparation of inorganic, organic, and composite coatings on the implants. It also presents some common subtractive processes applied for surface modifications of the biomaterials (i.e., acid etching, sand blasting, grit blasting, sand-blasted large-grit acid etched (SLA), anodizing, and laser methods). In summary, the article is an excellent compendium on the surface modifications and development of advanced osteoconductive and/or osteoinductive coatings on biomaterials for bone regeneration.

show abstract

Section: Peekmentioning

confidence: 99%

Osteoconductive and Osteoinductive Surface Modifications of Biomaterials for Bone Regeneration: A Concise Review

Kazimierczak

Przekora

2020

Coatings

View full text Add to dashboard Cite

show abstract

“…There is significant research on Ti-based alloy PEO coatings with high biocompatibility and in vivo effectiveness [18,25]. Some researchers have effectively anodized an alloy containing Zr and Nb, which opens up perspectives for the wide application of PEO for medical implant production [15]. To enhance antibacterial properties of the modified surface, antibiotics [33] and silver nanoparticles [23] have been added to the PEO solution.…”

Section: Bacterial Adhesion Testmentioning

confidence: 99%

“…Various surface modifications have been developed for market-available implants using subtractive and additive methods such as grit-blasting, acid etching, electrochemical anodic oxidation, or calcium-phosphate coatings [14]. The plasma electrolytic oxidation (PEO) treatment of dental and orthopedics implants is one of the most promising techniques due to the formation of strong bonds with metallic substrates [15]. There is extensive evidence of the PEO surface's effectiveness on Ti alloys, demonstrating increasing cell response and better osseointegration compared to the conventional implants [16][17][18].…”

Section: Introductionmentioning

confidence: 99%

“…There is extensive evidence of the PEO surface's effectiveness on Ti alloys, demonstrating increasing cell response and better osseointegration compared to the conventional implants [16][17][18]. There are a few studies about Zr-containing PEO implant coatings with successful outcomes [15], but there is lack of information about PEO-treatment of low-modulus ZrNb alloys for dental applications.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Formation of a Bacteriostatic Surface on ZrNb Alloy via Anodization in a Solution Containing Cu Nanoparticles

et al. 2020

View full text Add to dashboard Cite

High strength, excellent corrosion resistance, high biocompatibility, osseointegration ability, and low bacteria adhesion are critical properties of metal implants. Additionally, the implant surface plays a critical role as the cell and bacteria host, and the development of a simultaneously antibacterial and biocompatible implant is still a crucial challenge. Copper nanoparticles (CuNPs) could be a promising alternative to silver in antibacterial surface engineering due to low cell toxicity. In our study, we assessed the biocompatibility and antibacterial properties of a PEO (plasma electrolytic oxidation) coating incorporated with CuNPs (Cu nanoparticles). The structural and chemical parameters of the CuNP and PEO coating were studied with TEM/SEM (Transmission Electron Microscopy/Scanning Electron Microscopy), EDX (Energy-Dispersive X-ray Dpectroscopy), and XRD (X-ray Diffraction) methods. Cell toxicity and bacteria adhesion tests were used to prove the surface safety and antibacterial properties. We can conclude that PEO on a ZrNb alloy in Ca–P solution with CuNPs formed a stable ceramic layer incorporated with Cu nanoparticles. The new surface provided better osteoblast adhesion in all time-points compared with the nontreated metal and showed medium grade antibacterial activities. PEO at 450 V provided better antibacterial properties that are recommended for further investigation.

show abstract

“…The alloy has been used in various industries including aerospace, automotive, and biomedical applications. For the last section, however, researchers have claimed that toxic Al and V ions are released in a human body by wear and corrosion of the Ti-6Al-4V alloy [1]. This led to various endeavors to replace those alloying elements with safer ones, such as Nb, Ta, and Zr [2].…”

Section: Introductionmentioning

confidence: 99%

Kinetics of Capability Aging in Ti-13Nb-13Zr Alloy

et al. 2020

View full text Add to dashboard Cite

Metals for biomedical implant applications require a simultaneous achievement of high strength and low Young’s modulus from the viewpoints of mechanical properties. The American Society for Testing and Materials (ASTM) standards suggest two types of processing methods to confer such a mechanical performance to Ti-13Nb-13Zr alloy: solution treatment (ST) and capability aging (CA). This study elucidated the kinetics of CA process in Ti-13Nb-13Zr alloy. Microstructural evolution and mechanical change were investigated depending on the CA duration from 10 min to 6 h. The initial ST alloy possessed the full α′-martensitic structure, leading to a low strength, low Young’s modulus, and high ductility. Increasing CA duration increased mechanical strength and Young’s modulus in exchange for the reduction of ductility. Such a tendency is attributed to the decomposition of α′ martensite into (α+β) structure, particularly hard α precipitates. Mechanical compatibility (i.e., Young’s modulus compensated with a mechanical strength) of Ti-13Nb-13Zr alloy rarely increased by changing CA duration, suggestive of the intrinsic limit of static heat treatment.

show abstract

Incorporation of Ca ions into anodic oxide coatings on the Ti-13Nb-13Zr alloy by plasma electrolytic oxidation

Cited by 18 publications

References 38 publications

Osteoconductive and Osteoinductive Surface Modifications of Biomaterials for Bone Regeneration: A Concise Review

Osteoconductive and Osteoinductive Surface Modifications of Biomaterials for Bone Regeneration: A Concise Review

Formation of a Bacteriostatic Surface on ZrNb Alloy via Anodization in a Solution Containing Cu Nanoparticles

Kinetics of Capability Aging in Ti-13Nb-13Zr Alloy

Contact Info

Product

Resources

About