A field experiment was implemented in 2017/2018 winter season in privet farm at Nabarouh city, El-Dakahlia Governorate under open field conditions (31°06′52.3″ N 31°17′43.8″E) to study ֹ the effect of biological and mineral fertilizers on the productivity and quality of potato (Solanum tuberosum L, cv. Spunta). The experimental design was split-plot design with three replicates. The main treatments were without biofertilizer(B0) and with bio-fertilizer(B1) while the sub-main treatment was mineral fertilization at rates of (control = without KP-mineral fertilizer(KP0), 33%(KP1), 66%(KP2) and 100%(KP3) of potassium and phosphorus fertilizer recommendation dose for potato. The obtained results were: Biological fertilization (B1) gave the highest mean yield of fresh and dry weight, 15.72 and 2.86 ton.fed -1 , respectively compared with B0. Whereas 100% PK-mineral fertilization (KP3) gave the highest mean yield of fresh and dry weight which was 16.02 and 3.13 ton.fed -1 , respectively. In addition, the interaction treatment B1KP2 gave the highest mean yield of fresh and dry weight (17.15 and 3.43 ton.fed -1 ). Also, KP3 led to the highest percentage of N, P and K (%), they were 0.79, 0.276 and 1.89%, respectively. The interaction treatment of bio with 66% of mineral fertilizers (B1KP2) gave the highest significant increase of N, P and K% in potato tubers hence it may saving 34% of mineral fertilization. With regard to the quality parameters for potato, it was found that bio-fertilization (B1) was the best treatment for the quality characteristics as well as 66% of the recommended fertilizers dose and there were insignificant differences between B1KP2 and B1KP3.