Incidental Findings in Autopsy Examination of Liver: A Study of 70 Cases

Singal, Poonam; Kaur, Manpreet; Deepika, Deepika

doi:10.21276/aimdr.2017.3.3.pt9

Cited by 9 publications

(21 citation statements)

References 1 publication

(1 reference statement)

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“…Liver diseases predominated in males in the present study (86%) compared to females (14%). These findings were in close concordance with the study done by Singal et al [5] (2017) where maximum cases predominated in males (82.8 %). This may be attributed to the fact that men are more prone to alcohol consumption.…”

Section: Discussionsupporting

confidence: 93%

Spectrum of Hepatic Pathologies in Medicolegal Autopsies

2020

IJFMT

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Background: Silent liver disease is a major cause of morbidity and mortality in the population due to its silent progression to end stage liver disease without significant symptoms. We aim to study pattern of pathological findings and latent forms of diseases in the 100 liver autopsy specimen and to find clinicopathological correlation between clinical diagnosis and pathological diagnosis wherever possible. Method:The present study was conducted on 100 liver autopsy specimens received in the department of Pathology, Govt. Medical College, Patiala. Sections from representative areas were submitted for processing, sectioned and stained with Hematoxylin & Eosin stain.Results: Out of 100 specimens, 38 cases (38%) showed hepatic steatosis, followed by cirrhosis 14 cases(14%), chronic venous congestion 13 (13%) cases, portal triaditis 12 (12%) cases, normal 12 (12%) cases , hepatitis 8 (8%) cases , granulomatous/ tuberculosis pathology 2 (2%) cases and 1(1%)metastatic deposits of carcinoid tumour. Maximum cases seen in age group of 41-50 years with mean age 39.92±12.68 years. Liver disease predominated in males with male:female ratio of 6:1. Conclusion:Silent liver diseases are not uncommon. Autopsy examination of liver is very helpful to identify silent liver diseases like hepatic steatosis, cirrhosis, venous congestion and malignant tumours.

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Section: Discussionsupporting

confidence: 93%

Spectrum of Hepatic Pathologies in Medicolegal Autopsies

2020

IJFMT

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“…14 Liver cirrhosis was coincidently diagnosed in 13.5-40% of patients at autopsy by Iwarmiral and Inaba R. 15 Liver is a common site of granuloma formation owing to its rich blood supply. 3 In present study only 3 cases were recorded under inflammatory lesions in liver. Predominant cause was tuberculosis.…”

Section: Discussionmentioning

confidence: 62%

“…Single P et al, Bal MS et al, and Fubara DS et al, studies had peak incidence of liver diseases during 5th decade This difference in age population is attributed to low socioeconomic status of study population and early exposure to alcohol abuse. 3,5,6 Likewise, similar studies done by various scholars found that men were more prone to death by liver diseases (59.26%). As compared to women (40.8%) ( Table 2).…”

Section: Discussionmentioning

confidence: 65%

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Comparative study of pathological lesions of liver in autopsy cases

Simon¹,

Dantkale²,

Shinde³

2020

Int J Res Med Sci

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Background: Liver is a site for plethora of diseases among which many become symptomatic while others usually either go undiagnosed or are concealed by other prominent diseases. As said about liver to be the custodian of milieu interior most of the silent liver diseases are diagnosed only on autopsy examination. Aims and objectives was to study various pathological lesions of liver in medicolegal and clinical autopsy cases and to corelate liver diseases with age and sex. Retrospective cross-sectional observational study of 649 medicolegal and clinical autopsies conducted within 2 years of duration (January 2017 to December 2018).Methods: Out of all 649 autopsies conducted in our hospital all liver specimens along with other organs viscera were collected and formalin fixed. After gross examination sections from the liver were submitted for tissue processing and then stained with haematoxylin and eosin stain.Results: The most common pathology found in our study was fatty change (11.1%) followed by venous congestion (4.3%), hepatitis (3.5%), cirrhosis (2.2%), tuberculosis/ granulomatous hepatitis (0.6%), chronic hepatitis (0.3%), malignancy (1%), miscellaneous (2%) and normal (72.4%). Maximum cases were in 21-30 years of age group with male preponderance.Conclusions: Autopsy examination of liver is an effective tool to identify silent liver diseases. Use of autopsy findings along with other investigative techniques.

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“…The high incidence of fatty change in liver is because a large percentage of people in this region take alcohol which is major causative factor for developing fatty change. Regular intake of alcohol between 40-80 g m increases the liver weight and frequency of fatty changes in liver [7]. The understanding of hepatic steatosis has progressed considerably in recent years.…”

Section: Discussionmentioning

confidence: 99%

Liver autopsy study – incidental pathological findings

Behera

Sahu

Nayak

et al. 2017

Trop J Pathol Microbiol

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Background: Liver is the site of many diseases, many of which become symptomatic wh ile some are diagnosed only on autopsy. Involvement of liver is secondary to cardiac, metabolic, social problem like alcoholism, drug toxicity, injudicious use of topical applications, herbal remedies and environ mental exposures. Ai ms and Objecti ves: In apparently healthy individuals autopsy study sometimes reveals liver diseases. Hence this study aims at finding the frequency and the histopathological appearances in random liver autopsy, so as to evoke public awareness against alcoholis m, drug to xicity and potential toxins (perfu mes, shampoo, cleaning solvents, pesticides fertilizers,). Materials and Methods: The present study was carried out in the Depart ment of Pathology & Depart ment of Forensic Medicine and Toxicology, VIMSAR, Burla, Odisha over a period of 2 years. The liver specimens collected fro m 64 cases were examined grossly as well as microscopically to establish the presence of liver d iseases and also to find out the types of liver d iseases. Results: Out of 64 specimens, fatty change, chronic venous congestion, hepatitis, cirrhosis, Steatohepatitis, and drug toxicity cases are reported; fatty change being the predominant finding. Liver d iseases predominated in males with male to female ratio of 5:1. Conclusion: Autopsy examination of liver was very helpful to identify silent liver diseases.

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Incidental Findings in Autopsy Examination of Liver: A Study of 70 Cases

Cited by 9 publications

References 1 publication

Spectrum of Hepatic Pathologies in Medicolegal Autopsies

Spectrum of Hepatic Pathologies in Medicolegal Autopsies

Comparative study of pathological lesions of liver in autopsy cases

Liver autopsy study – incidental pathological findings

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