Incidencia, mortalidad y supervivencia por cáncer colorrectal en Cali, Colombia, 1962-2012

Cortés, Armando; Bravo, Luis Eduardo; García, Luz Stella; Collazos, Paola

doi:10.21149/spm.v56i5.7371

Cited by 18 publications

(16 citation statements)

References 41 publications

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“…[ 3 , 14 , 27 – 29 ] Our findings are, however, consistent with previous reports suggesting a higher CRC incidence in Colombian women. [ 5 , 14 ] Interestingly, when we carried sex-stratified analysis, we found that compared with men, a statistically significant higher proportion of female cases had normal BMI at CRC diagnosis (55% vs 46%), diagnosed at younger age (30% female cases had early-onset CRC, compared with 23% males), and reported higher family history of cancer (15% vs 10%). Our findings of a higher proportion of female CRC cases having normal BMI are consistent with previous studies that failed to detect consistent association between obesity and CRC cases in females, in contrast to males.…”

Section: Discussionmentioning

confidence: 92%

Clinical manifestations of colorectal cancer patients from a large multicenter study in Colombia

et al. 2016

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Colorectal cancer (CRC) is a major public health problem, and its incidence is rising in developing countries. However, studies characterizing CRC clinicopathological features in cases from developing countries are still lacking. The goal of this study was to evaluate clinicopathological and demographic features in one of the largest CRC studies in Latin America.The study involved over 1525 CRC cases recruited in a multicenter study in Colombia between 2005 and 2014 as part of ongoing genetic and epidemiological studies. We gathered clinicopathological data such as age at diagnosis, sex, body mass index, tobacco and alcohol consumption, family history of cancer, and tumor features including location, histological type, and stage. Statistical analyses were performed to test the association between age of onset, sex, and clinical manifestations.The average age at CRC diagnosis was 57.4 years, with 26.5% of cases having early-onset CRC (diagnosed by age 50 years). Most cases were women (53.2%; P = 0.009), 49.2% were overweight or obese, 49.1% were regular alcohol drinkers, 52% were smokers/former smokers, and 12.2% reported relatives with cancer. Most tumors in the study were located in the rectum (42.7%), were adenocarcinomas (91.5%), and had advanced stage (T3–T4, 79.8%). Comparisons by sex found that male cases were more likely to be obese (36.5% vs 31.1%; P = 0.001), less likely to have a family history of cancer (9.7% vs 15.3%; P = 0.016), and more likely to have advanced-stage tumors (83.9% vs 76.1%; P = 0.036). Comparisons by age of onset found that early-onset cases were more likely to be women (59.3% vs 51.0%; P = 0.005) and report a family history of cancer (17.4% vs 10.2%; P = 0.001).To our knowledge, our study is the largest report of clinicopathological characterization of Hispanic CRC cases, and we suggest that further studies are needed to understand CRC etiology in diverse Hispanic populations.

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Section: Discussionmentioning

confidence: 92%

Clinical manifestations of colorectal cancer patients from a large multicenter study in Colombia

et al. 2016

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“…The incidence and mortality due to colorectal cancer continues to rise in males and females in Cali. The reasons are that the screening activities are incipient, and the risk factors are difficult to control or are not clearly identified 41 ; it is a priority to promote an organized screening program to reverse the current trend. Until this intervention occurs, oncological care services must be oriented to the early diagnosis of suspected cases.…”

Section: Discussionmentioning

confidence: 99%

“…La incidencia y mortalidad por cáncer colo-rectal continua en ascenso en hombres y mujeres de Cali porque hasta el momento son incipientes las actividades de tamización y los factores de riesgo son difíciles de intervenir y/o no se encuentran claramente identificados 41 ; es prioritario impulsar un programa organizado de cribado para revertir la tendencia actual. Hasta tanto ocurra esta intervención la atención oncológica debe orientarse al diagnóstico temprano de los casos sospechosos.…”

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Reliable information for cancer control in Cali, Colombia

Bravo¹,

García²,

Collazos

et al. 2018

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Background: The Cali Population Cancer Registry (RPCC) has been in continuous operation since 1962 with the objective of producing valid statistics on the incidence of cancer, its patterns, trends and survival rates.Methods: During the period 2008-2012, 23,046 new cases were registered and during 2011-2015 there were 12,761 cancer deaths. The trend of the rates was described with the APC average annual change rate and with the Joinpoint analysis. We analyzed the individual data of 38,671 adults (15-99 years) diagnosed with cancer between 1995-2009, and we calculated the standardized net survival by age for the 14 most common cancer body sites, using the Pohar-Perme method.Results: Prostate and breast cancer were the first cause of cancer morbidity. The incidence rates in these were susceptible to early detection, tumors stabilized after decades of growth, while an increase in the incidence of colon cancer and papillary thyroid carcinoma was observed. The incidence rates of cervical and stomach cancer and conditions related to infectious agents decreased, although the number of absolute cases increased, due to the growth and aging of the population. Gastric cancer was responsible for the highest number of cancer related deaths. The types of cancer related to tobacco consumption (lung, oral cavity, esophagus, pancreas, urinary bladder) showed low numbers and a tendency to decrease. During the period 2000-2004, the 5-year net survival improved for cancers of the breast, cervix, prostate, melanoma and thyroid, although in the period 2005-2009 a stagnation was observed. In stomach, liver and lung cancer, the 5-year net survival was less than 15%. The 5-year overall survival in children was 51.0% (95% CI: 47.5, 54.3) and in adolescents 44.6% (95% CI: 36.0, 52.8).Comment: RPCC has been an advisor to the Colombian government in the evaluation of CPRs in the country and its data has contributed significantly to different aspects of cancer control in Colombia.

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“…The majority of Colombians live in capital cities, few follow the recommendations of exercising a minimum of 150 minutes a week and the prevalence of overweightness is an increasing trend. This condition is more prevalent in women and in the 50 to 64 age group 26 , 27 .…”

Section: Discussionmentioning

confidence: 99%

Cancer incidence and mortality in Medellin-Colombia, 2010-2014

Bohórquez¹,

Restrepo²,

Amell³

2018

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Background: This study provides information on cancer incidence and mortality in a Colombian population during 2010-2014, based on the data and methodology of the Population-based Cancer Registry of Antioquia to facilitate the implementation of cancer control strategies. Methods: This is a descriptive study of cancer incidence and mortality in a population, residing in the urban area of the municipality of Medellin. The cancers included in the study are those prioritized in the cancer control plan for Colombia (PDCC-cancers). The collection, processing and systematization of the data were performed in accordance with internationally standardized parameters for population cancer registries. Incidence and mortality rates were calculated by gender, age and tumor location.Results: During 2010-2014 there were 22,379 new cancer cases recorded in the urban area of the municipality of Medellin, of which 43.5% corresponded to the PDCC-cancers. During the same period, 14,922 cancer deaths were reported, 23.5% related to the PDCC-cancers, 53.5% in women. Prostate cancer and breast cancer were the principal cause of morbidity in men and women, respectively, and lung cancer was the principal cause of death for both sexes.Conclusion: Cancer is a health problem for the population of Medellin. It is necessary to emphasize research and monitor risk factors, the health response and the capacity of the health provider network when facing the growing demand caused by this epidemic.

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Incidencia, mortalidad y supervivencia por cáncer colorrectal en Cali, Colombia, 1962-2012

Cited by 18 publications

References 41 publications

Clinical manifestations of colorectal cancer patients from a large multicenter study in Colombia

Clinical manifestations of colorectal cancer patients from a large multicenter study in Colombia

Reliable information for cancer control in Cali, Colombia

Cancer incidence and mortality in Medellin-Colombia, 2010-2014

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