Incidence of Preoperative Deep Vein Thrombosis in Calcaneal Fractures

Williams, Joseph; Little, Milton T. M.; Kramer, Patricia Ann; Benirschke, Stephen K.

doi:10.1097/bot.0000000000000568

Cited by 27 publications

(16 citation statements)

References 15 publications

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“…In the present study, patients with lower extremity fractures at the age of > 60 years were found to have the highest incidence of DVT (6.6%), and this was similar to the ndings of Williams et al [7] . In the opinion of the present authors, there are more internal diseases in elderly patients, which results in a longer preparation time for surgery and longer preoperative resting time.…”

Section: Discussionsupporting

confidence: 92%

“…For instance, a previous study has shown that DVT is most common in middle-aged patients with lower extremity fractures, but there is no difference in its incidence between sexes [4] . Different from the results of that study, Williams et al suggested that older age is a risk factor for DVT [7] . In a study involving 829 patients, the incidences of DVT in patients with hip, femur shaft, knee, lower leg, and foot or ankle fractures were found to be 16.7%, 12.2%, 9%, 3.7%, and 2.3%, respectively [8] .…”

Section: Introductioncontrasting

confidence: 70%

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Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Chang

Wang

et al. 2020

Preprint

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Abstract Background:The objective of this work is to discuss and analyze the related factors of lower extremity fracture complicated by deep vein thrombosis (DVT), and to help surgeons aptly prevent it.Methods:A retrospective analysis was conducted on the orthopedic inpatient records of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from July 2014 to November 2018, and 11,891 patients with closed fractures of lower extremities were selected.By analyzing each patient's gender, age, presence or absence of diabetes and hypertension,preoperative plasma D-dimer level, and color Doppler ultrasound of the lower extremity vein, the pertinent factors of the patients with lower extremity fractures complicated by DVT were analyzed.Results: A total of 11,891 patients were selected, including 4462 with cases of peri-hip fractures, 754with cases of femoral shaft fractures, 1776 with cases of peri-knee fractures, 1961 with cases of tibiofibular fractures, and 2938 with cases of ankle fractures.Of these patients, 643 with DVT were detected, displaying a total incidence of 5.4%.All patients were categorized into either the DVT group or non-DVT group.The results demonstrate that there were statistically significant differences between the two groups in age, the presence of diabetes and hypertension, the fracture site, and the preoperative plasma D-dimer level (p<0.05), but there was no statistically significant difference in sex (p>0.05). Logistic multivariate analysis revealed that age, the presence of diabetes, and the preoperative plasma D-dimer level of patients were independent risk factors for lower extremity fracture complicated by DVT.Conclusion: Age, the presence of diabetes and hypertension, the fracture site, and the preoperative plasma D-dimer level were found to be correlated with the incidence of DVT. Moreover,age, the presence of diabetes, the preoperative fracture site, and the plasma D-dimer level were found to be independent risk factors.

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Section: Discussionsupporting

confidence: 92%

Section: Introductioncontrasting

confidence: 70%

Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Chang

Wang

et al. 2020

Preprint

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“…In a study of one hundred fifty-nine patients, Williams suggested that older age was a risk factor for DVT, but body mass index and sex were not significant predictors. 9 In another study of nine hundred one consecutive patients, Park 10 suggested an advanced age, cardiovascular disease, and chronic lung disease were independent risk factors.Michetti 11 and Chen 12 also analyzed the risk factors of DVT in fracture patients. However, there were controversial conclusions in studies, and it is necessary to perform more studies to clarify these issues.…”

Section: Introductionmentioning

confidence: 98%

Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Chen

Wang

et al. 2018

Pak J Med Sci

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Objective:To clarify if fracture site is correlated to the occurrence of deep venous thrombosis, and determine the risk factors of deep venous thrombosis in lower extremity fractures, help surgeons make prophylaxis for the disease correctly.Methods:The patients with lower extremity fractures treated surgically in the orthopedics department of our hospital from May 2012 to July 2017 were reviewed retrospectively. The clinical data including age, gender, fracture site, surgery modality, hospital stay, operation time, occupation type, hypertension, coronary heart disease, diabetes, smoking status, drinking status, postoperative exercises were collected and analyzed.Results:Eight hundred and twenty-nine patients were included for analysis, in which 68 were included in deep venous thrombosis group, 761 were included in the non-deep venous thrombosis group, and the incidence of deep venous thrombosis was 8.2%. There were significant differences in age, fracture site, surgery modality, occupation type, operation time, smoking status, hospital stay and postoperative exercises between the two groups (p<0.05), but no significant differences in gender, drinking status, coronary heart disease, diabetes and hypertension (p>0.05). In multivariate analysis, old age greater than 50 years, arthroplasty and operation time more than three hours were independent risk factors, while physical labor and postoperative exercises were protective factors for deep venous thrombosis in lower extremity fractures.Conclusion:Fracture site was correlated to the incidence of deep venous thrombosis, old age, longer operation time, and arthroplasty were independent risk factors, physical labor and postoperative exercises were protective factors for deep venous thrombosis in patients with lower extremity fractures.

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“…Extensive and deep understanding the epidemiologic characteristics of DVT, particularly the relevant risk factors, was of extreme importance in prevention of this key adverse event. By far, multiple risk factors associated with DVT have been identified, including advanced age, male gender, obesity, a history of DVT or pulmonary embolism, immobility, smoking or fracture itself [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Relationship between the Inflammation/immune Indexes and Deep Venous Thrombosis (DVT) following Tibial Plateau Fractures

Liu¹,

Chen²,

Li³

et al. 2020

Preprint

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Objective To determine the relationship between inflammation/immune-based indexes and preoperative DVT of lower extremities following tibial plateau fracturesMethods Retrospective analysis of a prospectively collected data on patients undergoing surgeries of tibial plateau fractures between October 2014 and December 2018 was performed. Duplex ultrasonography (DUS) was routinely used to screen for preoperative DVT of bilateral lower extremities. Data on biomarkers (neutrophil-, lymphocyte-, monocyte- and platelet counts) at admission were collected, based on which neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte/lymphocyte (MLR) and systemic immune-inflammation index (SII, neutrophil* platelet/ lymphocyte) were calculated. Receiver operating characteristic (ROC) was used to determine the optimal cut-off value for each variable. Multivariate logistic regression analysis was used to evaluate the independent relationship of each biomarker or index with DVT, after adjustment for demographics, co-morbidities and injury-related variables.Results Among 1179 patients included, 16.3% (192/1179) of them had (16.3%) had a preoperative DVT. Among the biomarkers and indexes, only platelet and neutrophil were identified to be independently associated with DVT, and their predictive ability was stable regardless of open fracture with or without included. The other independent variables were elevated D-dimer level (>0.55mg/L), male gender and hypertension in the sensitivity analysis with open fractures excluded.Conclusion These identified factors are conducive to the initial screening for patients at-risk of DVT, individualized risk assessment, risk stratification and accordingly development of targeted prevention programs.

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Incidence of Preoperative Deep Vein Thrombosis in Calcaneal Fractures

Cited by 27 publications

References 15 publications

Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Relationship between the Inflammation/immune Indexes and Deep Venous Thrombosis (DVT) following Tibial Plateau Fractures

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