Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Li, Qiang; Chen, Xiao; Wang, Yuanyuan; Li, Lin

doi:10.12669/pjms.344.14752

Cited by 16 publications

(37 citation statements)

References 16 publications

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“…Moreover, elderly patients often have vascular sclerosis, high blood viscosity, and poor venous valve function, which lead to a high incidence of lower extremity DVT [17] . Moreover, similar to the ndings of the present study, Li et al found that femoral neck fractures and intertrochanteric fractures are more common in older patients, and that many patients with these fractures choose arthroplasty surgery, which also increases the risk of DVT [8] .…”

Section: Discussionsupporting

confidence: 90%

“…Furthermore, in the cohort study, the fracture site was found to be an independent risk factor for DVT in lower extremities after fracture, and the incidence of DVT in patients with peri-hip fractures was 7.0%. Peri-hip fractures are more common in older patients, and many patients with these fractures choose arthroplasty surgery; this is one of the reasons for the high incidence of DVT following peri-hip fractures [8] . Some researchers have also con rmed that hip fracture is an important risk factor for, and is signi cantly associated with, the occurrence of DVT [9] .…”

Section: Discussionmentioning

confidence: 99%

“…Different from the results of that study, Williams et al suggested that older age is a risk factor for DVT [7] . In a study involving 829 patients, the incidences of DVT in patients with hip, femur shaft, knee, lower leg, and foot or ankle fractures were found to be 16.7%, 12.2%, 9%, 3.7%, and 2.3%, respectively [8] . In another study of 462 patients, 71.2% of patients with DVT had hip fractures, 11.9% had tibio bular fractures, and 10.4% had femoral shaft fractures [9] .…”

Section: Introductionmentioning

confidence: 99%

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Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Chang

Wang

et al. 2020

Preprint

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Abstract Background:The objective of this work is to discuss and analyze the related factors of lower extremity fracture complicated by deep vein thrombosis (DVT), and to help surgeons aptly prevent it.Methods:A retrospective analysis was conducted on the orthopedic inpatient records of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from July 2014 to November 2018, and 11,891 patients with closed fractures of lower extremities were selected.By analyzing each patient's gender, age, presence or absence of diabetes and hypertension,preoperative plasma D-dimer level, and color Doppler ultrasound of the lower extremity vein, the pertinent factors of the patients with lower extremity fractures complicated by DVT were analyzed.Results: A total of 11,891 patients were selected, including 4462 with cases of peri-hip fractures, 754with cases of femoral shaft fractures, 1776 with cases of peri-knee fractures, 1961 with cases of tibiofibular fractures, and 2938 with cases of ankle fractures.Of these patients, 643 with DVT were detected, displaying a total incidence of 5.4%.All patients were categorized into either the DVT group or non-DVT group.The results demonstrate that there were statistically significant differences between the two groups in age, the presence of diabetes and hypertension, the fracture site, and the preoperative plasma D-dimer level (p<0.05), but there was no statistically significant difference in sex (p>0.05). Logistic multivariate analysis revealed that age, the presence of diabetes, and the preoperative plasma D-dimer level of patients were independent risk factors for lower extremity fracture complicated by DVT.Conclusion: Age, the presence of diabetes and hypertension, the fracture site, and the preoperative plasma D-dimer level were found to be correlated with the incidence of DVT. Moreover,age, the presence of diabetes, the preoperative fracture site, and the plasma D-dimer level were found to be independent risk factors.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Chang

Wang

et al. 2020

Preprint

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“…The analysis results implied that the rate of DVT after a major orthopaedic surgery seems to range between 0.6% and 71.2% in various fracture sites, while hip fractures bear the highest risk of DVT, followed by tibiofibular fracture and femoral shaft fracture. Many authors also demonstrated that hip fracture was a considerable risk factor for DVT and had a significant correlation with the occurrence of DVT 39. In general, patients who undergo a hip fracture exhibit all three risk factors associated with Virchow’s triad, which contribute to the high occurrence of DVT 40.…”

Section: Discussionmentioning

confidence: 99%

A Retrospective cohort study on the risk factors of deep vein thrombosis (DVT) for patients with traumatic fracture at Honghui Hospital

Zhang

Huai

Wang³

et al. 2019

BMJ Open

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ObjectiveTo explore the risk factors of perioperative deep vein thrombosis (DVT) in patients with traumatic fracture after orthopaedic surgery and their potential diagnostic values in clinical.DesignRetrospective cohort study.SettingClinical Laboratory of Honghui Hospital, Xi’an JiaoTong University College of Medicine, Xi’an, Shaanxi, China.Materials and methodsA retrospective cohort study was conducted with surgically treated fracture patients in Honghui Hospital from 1 May 2016 to 31 February 2017.χ2test, independent sample t test and regression analysis were applied to examine the correlation between perioperative DVT and the factors of preoperative time, fracture sites, D-dimer value and chronic diseases (hypertension, diabetes and coronary disease).Results462 patients were enrolled for analysis. The preoperative time of patients with DVT was significantly longer than that of non-DVT patients (7.14±5.51 vs 5.45±3.75) (P<0.01).χ2test showed the significant differences in the rate of DVT among patients with different fracture sites (P<0.01). By the receiver-operating characteristic curve analysis, the cut-off value of preoperative D-dimer and postoperative D-dimer in diagnosing perioperative DVT was 4.01 µg/mL and 5.03 µg/mL, respectively. Area under the curve was 0.593 (95% CI 0.533 to 0.652) and 0.728 (95% CI 0.672 to 0.780), respectively. The sensitivity and specificity of preoperative D-dimer for DVT diagnosis were 71.30% and 44.83%, and as for postoperative D-dimer were 63.90% and 70.51%.ConclusionsFracture site was correlated to the incidence of DVT; prolonged preoperative time and increased D-dimer value were independent risk factors for DVT in patients with lower extremity traumatic fractures.

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“… 1 It is estimated that a large number of patients, approximately 200 000 people, die from pulmonary embolism in the world each year. 2 Consequently, how to prevent the occurrence of DVT in patients after surgeries is highly valued in the field of medicine.…”

Section: Introductionmentioning

confidence: 99%

Analysis of risk factors for lower limb deep vein thrombosis in patients after Lumbar Fusion Surgery

Chen

et al. 2020

Pak J Med Sci

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Objective: To identify the risk factors of deep vein thrombosis (DVT) of lower limb in patients undergoing lumbar fusion surgeries, to provide a better understanding of DVT and take prophylactic measures. Methods: This study was carried out in our hospital between January 2016 and February 2020, patients undergoing lumbar fusion surgeries were included and divided into DVT group and non-DVT group, and the medical data including basic demographics, clinical characteristics, operative data, and routine biochemical parameters were collected and analyzed. Results: In the current study, 390 cases were included, 48 cases were enrolled in DVT group and 342 in non-DVT group. The incidence of DVT was 12.3%. There were significant differences in age, hyperlipemia, hypertension, occupation type, D-dimer level, hospital stay, and postoperative exercises (p<0.05), but no significant differences in gender, smoking status, drinking status, coronary heart disease, diabetes mellitus, fused segments, and operation time (p>0.05) between the two groups. In multivariate analysis, age>50 years, hypertension, D-dimer>500ug/L were independent risk factors, while postoperative exercises were protective factor for DVT. Conclusion: Those patients undergoing lumbar fusion surgeries should take more prophylactic measures including postoperative exercises if they were elderly, or hypertensive, or have high D-dimer level, in order to decrease the incidence of DVT. doi: https://doi.org/10.12669/pjms.37.1.3041 How to cite this:Li Q, Yu Z, Chen X, Zhang W. Analysis of risk factors for lower limb deep vein thrombosis in patients after Lumbar Fusion Surgery. Pak J Med Sci. 2021;37(1):239-243. doi: https://doi.org/10.12669/pjms.37.1.3041 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study

Cited by 16 publications

References 16 publications

Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

Study on the Risk Factors of Deep Vein Thrombosis (DVT) in Patients With Lower Extremity Fracture

A Retrospective cohort study on the risk factors of deep vein thrombosis (DVT) for patients with traumatic fracture at Honghui Hospital

Analysis of risk factors for lower limb deep vein thrombosis in patients after Lumbar Fusion Surgery

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