Incidence of Dermatomyositis and Clinically Amyopathic Dermatomyositis

Abstract

To identify new and existing cases of dermatomyositis and its subtypes in Olmsted County, Minnesota, from 1976 through 2007, and to establish a population-based estimate of the incidence and prevalence of dermatomyositis and amyopathic dermatomyositis.

Prevalence and incidence in patients with autoimmune rheumatic diseases: A nationwide population‐based study in Taiwan

“…The estimated annual incidence rate of PM and DM varies between 1.9 and 7.7 per million (37). Between 1976 and 2007, a study in Olmsted County, Minnesota, showed that the overall age-and sex-adjusted incidence of DM, including all subtypes, was 9.63 per million persons (38). In the present study, the prevalence of PM and DM was 1.5 per 100,000 persons and 1.6 per 100,000 persons, respectively, which was lower than that reported in a previous study (36).…”

Inflammatory Myopathies with Cutaneous Involvement: from Diagnosis to Therapy

“…43 Patients with amyopathic dermatomyositis (ADM) have the same cutaneous manifestations as those with classic DM, but without clinical or laboratory evidence of myopathy for at least 6 months. 4,10 Some authors even propose the term "hypomyopathic dermatomyositis" for those DM patients who have no subjective muscle weakness, but with objective evidence of subclinical muscle affection in electromyography or muscle biopsy. 10 Later, ADM in some patients may transform to classic DM, and if these patients have anti-MDA5 antibodies in sera they are potentially at risk for developing interstitial lung disease.…”

“…4,10 Some authors even propose the term "hypomyopathic dermatomyositis" for those DM patients who have no subjective muscle weakness, but with objective evidence of subclinical muscle affection in electromyography or muscle biopsy. 10 Later, ADM in some patients may transform to classic DM, and if these patients have anti-MDA5 antibodies in sera they are potentially at risk for developing interstitial lung disease. 32,44 It is estimated that approximately 75% of adolescents with amyopathic juvenile DM will remain free from muscle disease after years of follow-up, while the other 25% of them will cover the typical clinical features of classic juvenile DM.…”

“…9 Dermatomyositis is a relatively rare disorder, with incidence varying between 2 and 19 cases per 1 million population. 10,11 It affects women about twice as frequently as it does men. 11,12 The age distribution shows a bimodal pattern with an initial peak at 10 years of age for juvenile DM and a second larger peak between 40 and 60 years of age.…”

Coexistencia entre polimiositis y enfermedad de Castleman; presentación de un caso.

“…La incidencia reportada se ha estimado en 9.63 x 1.000.000 habitantes por año con predominio en el género femenino en una relación de dos a uno, siendo su pico de edad entre los 40 a 50 años. 13,14 Se ha descrito de manera muy esporádica la asociación entre la enfermedad de Castleman y enfermedades autoinmunes, sobre todo con la polimiopatía inflamatoria idiopática. A continuación se presenta el caso de una paciente con manifestaciones de enfermedad autoinmune sistémica acompañada de lesión pélvica, compatible con enfermedad de Castleman.…”