In Vivo Measurement of Longitudinal Chromatic Aberration in Patients Implanted With Trifocal Diffractive Intraocular Lenses

Viñas, María; Gonzalez-Ramos, Ana; Dorronsoro, Carlos; Akondi, Vyas; Garzón, Nuria; Poyales, Francisco; Marcos, Susana

doi:10.3928/1081597x-20170814-01

Cited by 20 publications

(28 citation statements)

References 31 publications

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“…The chromatic characterization of IOLs on optical bench, using in-vitro techniques and model eyes [7,10,11] to evaluate a variety of physical metrics based on the energy efficiency and modulation transfer function (MTF), does not provide an immediate and comprehensive understanding of its impact on vision. Some researchers have developed optical setups based on either wavefront sensing, laser ray tracing, double-pass retinal images, and psychophysical techniques to precisely and effectively measure LCA in vivo of pseudophakic patients [12] even at various focus distances [13]. Such optical setups frequently involve the use of sophisticated equipment with strict alignment requirements, the assistance of highly specialized personnel, and the recruitment of collaborative patients for time-consuming trials.…”

Section: Introductionmentioning

confidence: 99%

“…To be suitable for the clinical practice, the apparatus and the examination procedure should be based on an effective in vivo measurement technique. Currently, these techniques apply either subjective psychophysical or objective reflectometric methods [13]. In case of considering a subjective psychophysical method, some properties are particularly valuable:…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical assessment of chromatic aberration in phakic and pseudophakic eyes using a simple autorefractor

Millán¹,

Vega²,

Poyales³

et al. 2019

Biomed. Opt. Express

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We describe a psychophysical method and a simple setup-an autorefractor with a Scheiner disc, sequentially illuminated with red and blue lights-for the clinical assessment of the longitudinal chromatic aberration (LCA) in phakic and pseudophakic patients. This method applies to the unaccommodated eye, even in the presence of positive or negative refractive errors and astigmatism. It measures the chromatic difference of refraction as an estimate of LCA. We built a proof of concept from inexpensive and off-the-shelf optomechanical components with which we obtained the preliminary clinical results presented in the paper. We considered one control group of phakic patients and three groups of pseudophakic patients with monofocal implants of different designs and materials. The results, satisfactory and consistent with those reported by other researchers in related works, demonstrate the method and system feasibility.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical assessment of chromatic aberration in phakic and pseudophakic eyes using a simple autorefractor

Millán¹,

Vega²,

Poyales³

et al. 2019

Biomed. Opt. Express

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show abstract

“…It was verified that the use of polychromatic TF VS ratio did not alter the evaluation of the theoretical SimVis temporal profiles in all M-IOL designs that do not involve longitudinal chromatic aberration (LCA) modulation [15]. However, the use of polychromatic SimVis temporal profile can improve [15], to a small extent, the replication of the TF VS ratio of the M-IOL that has the ability to correct the LCA [20] at specific distances.…”

Section: Discussionmentioning

confidence: 90%

Experimental validations of a tunable-lens-based visual demonstrator of multifocal corrections

Akondi

Sawides²,

Marrakchi³

et al. 2018

Biomed. Opt. Express

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The Simultaneous Vision simulator (SimVis) is a visual demonstrator of multifocal lens designs for prospective intraocular lens replacement surgery patients and contact lens wearers. This programmable device employs a fast tunable lens and works on the principle of temporal multiplexing. The SimVis input signal is tailored to mimic the optical quality of the multifocal lens using the theoretical SimVis temporal profile, which is evaluated from the through-focus Visual Strehl ratio metric of the multifocal lens. In this paper, for the first time, focimeter-verified on-bench validations of multifocal simulations using SimVis are presented. Two steps are identified as being critical to accurate SimVis simulations. Firstly, a new iterative approach is presented that improves the accuracy of the theoretical SimVis temporal profile for three different multifocal intraocular lens designs -diffractive trifocal, refractive segmented bifocal, and refractive extended depth of focus, while retaining a low sampling. Secondly, a fast focimeter is used to measure the step response of the tunable lens, and the input signal is corrected to include the effects of the transient behavior of the tunable lens. It was found that the root-mean-square of the difference between the estimated through-focus Visual Strehl ratio of the multifocal lens and SimVis is not greater than 0.02 for all the tested multifocal designs.

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“…As found in phakic eyes the LCA reflectometric methods (wavefront sensing and retinal imaging) underestimated the LCA obtained from psychophysical measurements. In a subsequent study the psychophysical LCA was measured in patients implanted with trifocal diffractive lOLs with the same hydrophilic and hydrophobic designs. Measurements were performed at far, intermediate and near distances.…”

Section: Vision Applications Of Viobio Adaptive Optics Lab Technologiesmentioning

confidence: 99%

VioBio lab adaptive optics: technology and applications by women vision scientists

Marcos

Benedi-Garcia

Aissati

et al. 2020

Ophthalmic Physiologic Optic

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Purpose Adaptive Optics allows measurement and manipulation of the optical aberrations of the eye. We review two Adaptive Optics set‐ups implemented at the Visual Optics and Biophotonics Laboratory, and present examples of their use in better understanding of the role of optical aberrations on visual perception, in normal and treated eyes. Recent findings Two systems (AOI and AOII) are described that measure ocular aberrations with a Hartmann‐Shack wavefront sensor, which operates in closed‐loop with an electromagnetic deformable mirror, and visual stimuli are projected in a visual display for psychophysical measurements. AOI operates in infrared radiation (IR) light. AOII is provided with a supercontiniuum laser source (IR and visible wavelengths), additional elements for simulation (spatial light modulator, temporal multiplexing with optotunable lenses, phase plates, cuvette for intraocular lenses‐IOLs), and a double‐pass retinal camera. We review several studies undertaken with these AO systems, including the evaluation of the visual benefits of AO correction, vision with simulated multifocal IOLs (MIOLs), optical aberrations in pseudophakic eyes, chromatic aberrations and their visual impact, and neural adaptation to ocular aberrations. Summary Monochromatic and chromatic aberrations have been measured in normal and treated eyes. AO systems have allowed understanding the visual benefit of correcting aberrations in normal eyes and the adaptation of the visual system to the eye's native aberrations. Ocular corrections such as intraocular and contact lenses modify the wave aberrations. AO systems allow simulating vision with these corrections before they are implanted/fitted in the eye, or even before they are manufactured, revealing great potential for industry and the clinical practice. This review paper is part of a special issue of Ophthalmic & Physiological Optics on women in visual optics, and is co‐authored by all women scientists of the research team.

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In Vivo Measurement of Longitudinal Chromatic Aberration in Patients Implanted With Trifocal Diffractive Intraocular Lenses

Cited by 20 publications

References 31 publications

Clinical assessment of chromatic aberration in phakic and pseudophakic eyes using a simple autorefractor

Clinical assessment of chromatic aberration in phakic and pseudophakic eyes using a simple autorefractor

Experimental validations of a tunable-lens-based visual demonstrator of multifocal corrections

VioBio lab adaptive optics: technology and applications by women vision scientists

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