In vitro α-glucosidase and pancreatic lipase inhibitory activities and antioxidants of Samnamul (Aruncus dioicus) during rehydration and cooking

Perilla frutescens (Nga-Mon) is an annual herbaceous plant, reported for its antioxidant, anti-allergic, antiinflammatory and neuroprotective properties. The current study was conducted to compare the different pretreatment techniques followed by hexane extraction for perilla seed oil and its pharmaceutical values. There are no significant differences in the yield of seed oil after pre-treatments except sonication. All the pre-treatments diminish the endogenous lipase activity, peroxidation and degradation of the oil. Fatty acid content analysis revealed that the nutrient quality, with respect to fatty acid content, of perilla seed was not compromised with any of the pre-treatments of current study. The results of α-amylase, α-glucosidase and protein glycation inhibition assays suggested that tested perilla seed oils are pharmaceutical candidate for the treatment of carbohydrate related diseases, especially for diabetes. Selection of appropriate pre-treatment strategies will helps to extract the perilla seed oil without any compromise in its quality. The current study suggested that moist heat with pressure can be an appropriate pre-treatment method for perilla seed oil extraction.

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“…The addition of Perilla oil with Aruncus dioicus extract improved the total α-glucosidase inhibitory activity (Ahn et al, 2014).…”

Section: Introductionmentioning

confidence: 95%

Impact of different pre-treatment strategies on the quality of fatty acid composition, tocols content and metabolic syndrome related activities of Perilla frutescens seed oil

Sirilun¹,

Sivamaruthi²,

Pengkumsri³

et al. 2016

J App Pharm Sci

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“…Daraesoon in the form of mucknamul was purchased from National Forestry Cooperative Federation in Yeoju, Korea in 2013. Daraesoon was prepared using a standard procedure prior to cooking, as described previously by Ahn et al [ 16 ]. Briefly, the Daraesoon was soaked in cold water for 16 h, boiled in water for 30 min, re-soaked in cold water for 1 h, and then the excess water was removed by squeezing.…”

Section: Methodsmentioning

confidence: 99%

“…The shoot of A. arguta (Daraesoon) is a traditional Korean food; raw Daraesoon is collected only in the spring but it is difficult to store for a long period of time due to its high moisture content. Therefore, the majority of raw Daraesoon is blanched and then air-dried to make mucknamul, which can be stored for extended periods and is commercially available year round [ 16 ]. Mucknamul is soaked in water, boiled, and then re-soaked in cold water before being prepared as namul, a cooked Korean vegetable dish with seasonings.…”

Section: Introductionmentioning

confidence: 99%

Hypoglycemic and antioxidant effects of Daraesoon (Actinidia argutashoot) in animal models of diabetes mellitus

Lee

Kang²,

Choe

et al. 2015

Nutr Res Pract

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BACKGROUND/OBJECTIVESThe primary objective of the treatment of diabetes mellitus is the attainment of glycemic control. Hyperglycemia increases oxidative stress which contributes to the progression of diabetic complications. Thus, the purpose of this study was to investigate the hypoglycemic and antioxidant effects of Daraesoon (Actinidia arguta shoot) in animal models of diabetes mellitus.MATERIALS/METHODSRats with streptozotocin-induced diabetes received an oral administration of a starch solution (1 g/kg) either with or without a 70% ethanol extract of Daraesoon (400 mg/kg) or acarbose (40 mg/kg) after an overnight fast and their postprandial blood glucose levels were measured. Five-week-old C57BL/6J mice were fed either a basal or high-fat/high-sucrose (HFHS) diet with or without Daraesoon extract (0.4%) or acarbose (0.04%) for 12 weeks after 1 week of adaptation to determine the effects of the chronic consumption of Daraesoon on fasting hyperglycemia and antioxidant status.RESULTSCompared to the control group, rats that received Daraesoon extract (400 mg/kg) or acarbose (40 mg/kg) exhibited a significant reduction in the area under the postprandial glucose response curve after the oral ingestion of starch. Additionally, the long-term consumption of Daraesoon extract or acarbose significantly decreased serum glucose and insulin levels as well as small intestinal maltase activity in HFHS-fed mice. Furthermore, the consumption of Daraesoon extract significantly reduced thiobarbituric acid reactive substances and increased glutathione levels in the livers of HFHS-fed mice compared to HFHS-fed mice that did not ingest Daraesoon.CONCLUSIONSDaraesoon effectively suppressed postprandial hyperglycemia via the inhibition of α-glucosidase in STZ-induced diabetic rats. Chronic consumption of Daraesoon alleviated fasting hyperglycemia and oxidative stress in mice fed a HFHS diet.

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“…The perilla seed (PS) and PS oil (PSO) are rich sources of phenolic compounds, antioxidants, and polyunsaturated fatty acids (especially, α-linolenic acid, linoleic acid, oleic acid, and palmitic acid). Several reports revealed that the PS, PSO, and perilla leaves have antioxidant, antiallergic, antiinflammatory, anticancer, neuroprotective, and α-glucosidase inhibitory properties [1][2][3][4]. PSO is commonly used to flavor the foods, and as cooking oil (particularly in Korean cuisine), and in cleansing products.…”

Section: Introductionmentioning

confidence: 99%

Preparation and Stability Assessment of Perilla Frutescens Seed Oil Powder

Chaiyasut

Sivamaruthi

Makhamrueang

et al. 2017

Asian J Pharm Clin Res

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Objective: The present study deals with the preparation and stability assessment of Perilla frutescens seed oil powder (PSOP) by spray drying technique.Methods: Perilla oil emulsion was prepared with various combinations of emulsifiers and maltodextrin powder. The emulsion was dried in a spray dryer, and dried samples were packed and stored at 4, 25, and 40°C for 3 months. The changes in acid and peroxide value the fatty acid content of PSOP during storage were assessed. PSOP samples were subjected to scanning electron microscopic analysis to examine the size and shape of the particle.Results: About 9.52% of PSOP yield was obtained while 5% of whey protein was used as an emulsifier. The moisture content of the PSOP was 2.06 ± 0.23-3.08 ± 0.13%. The acid and peroxide values were increased from 1.49 ± 0.09 to 3.71 mg KOH/g of PSOP, 4.10-7.18 mEq/kg of PSOP, while stored in aluminum foil and kept at 40°C. About 39. 97, 26.68, 24.78, and 7.47% of linolenic, oleic, linoleic, and palmitic acids were found in PSOP, respectively. Conclusion:The study revealed that spray-dried PSOP was stable when stored in the absence of light and air at low temperature. The spray-dried PSOP is the best candidate for pharmacological and food applications.

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In vitro α-glucosidase and pancreatic lipase inhibitory activities and antioxidants of Samnamul (Aruncus dioicus) during rehydration and cooking

Cited by 18 publications

References 24 publications

Impact of different pre-treatment strategies on the quality of fatty acid composition, tocols content and metabolic syndrome related activities of Perilla frutescens seed oil

Impact of different pre-treatment strategies on the quality of fatty acid composition, tocols content and metabolic syndrome related activities of Perilla frutescens seed oil

Hypoglycemic and antioxidant effects of Daraesoon (Actinidia argutashoot) in animal models of diabetes mellitus

Preparation and Stability Assessment of Perilla Frutescens Seed Oil Powder

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