In Vitro Antioxidant Activity of the Aqueous Extract of Andrographis Paniculata and Carica Papaya Leaves

Abstract

Oxidative stress has been implicated in the pathogenesis of many human aliments. Since synthetic antioxidants produce harmful side effects, research has been intensified nowadays to evaluate the phyto antioxidants. Andrographis paniculata, popularly known as "king of bitters" is traditionally used in Indian system of medicine to cure various diseases. Carica papaya is a fruit bearing plant with many pharmacological activities. Hence in the present study, the antioxidant activity of aqueous extract of Andrographis paniculata and Carica papaya, leaves was evaluated by different in vitro assay models. Total antioxidant activity of the extract was also high. The free radical scavenging activity was comparable with standard ascorbic acid. Therefore, the selected plants could be considered as a very good antioxidant source with therapeutic potential.

Antioxidant activity and acute toxicity of two Lagenaria siceraria (Molina) Standl. varieties from Sudan

“…Free radicals, often called reactive oxygen species (ROS) and they are the core of any biochemical process representing a vital part in metabolism (Sangeetha and Venkatalakshmi, 2017). On the other hand, free radicals are highly generated in many pathological conditions and involved in the development and progress of common chronic degenerative diseases such as cardiovascular and neurodegenerative diseases, diabetes and cancer (Umeno et al, 2017).…”