In vitro and schematic model eye assessment of glare or positive dysphotopsia-type photic phenomena: Comparison of a new material IOL to other monofocal IOLs

Das, Kamal; Werner, Liliana; Collins, Stephen P.; Hong, Xin

doi:10.1016/j.jcrs.2018.09.017

Cited by 26 publications

(21 citation statements)

References 21 publications

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“…In laboratory testing with non-sequential ray-tracing evaluations, the Clareon® IOL has been shown to produce the main image beam without any secondary glare components whereas the Tecnis ZCB00® (an IOL very similar to the PCB00®) has shown secondary glare components. 44 In this study, we had only one patient in each group with negative dysphotopsias that resolved at 12 months follow up, probably due to neuroadaptation (table 7).…”

Section: Discussionmentioning

confidence: 89%

“…43 Of 9 hydrophobic acrylic IOLs in one study, Clareon® had the lowest edge thickness at 167.2 microns 43 while another found that the IOL designs with optic edge curvature and full functional optics, such as Clareon®, demonstrated the lowest level of glare-type photic phenomena. 44 The Clareon® IOL features a full 6.0 mm optic and a modified edge profile where the center point of the edge radius lies posterior to the optical plane, designed to reduce dysphototopsia. The Tecnis PCB00® employs optic bodies that incorporate additional peripheral non-imaging components, thus reducing the functional optic diameter.…”

Section: Discussionmentioning

confidence: 99%

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Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

Stanojcic

O’Brart

Hull

et al. 2020

J Cataract Refract Surg

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Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

Stanojcic

O’Brart

Hull

et al. 2020

J Cataract Refract Surg

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“…For example, halos and starbursts (i.e., positive dysphotopsia) can often follow cataract surgery and can vary according to intraocular lens type. 8 Glare disability and discomfort can be reduced by increasing retinal macular pigments (essentially increasing filtering in front of the cones), 9 but increased macular pigment has little or no effect on the amount of intraocular scatter arising from the anterior portions of the eye 10 (absorbance by macular pigment would also not influence the effects of scatter outside the spatial area where the pigments absorb light).…”

Section: Introductionmentioning

confidence: 99%

The effects of light scatter when using a photochromic vs. non-photochromic contact lens

Hammond

Buch

Hacker³

et al. 2020

Journal of Optometry

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Purpose To assess the visual effects of wearing both an activated and an inactivated photochromic contact lens, with a direct comparison to a non-photochromic contact lens worn in the fellow eye. This study focused on the visual effects of scatter quantified as the minimum distance between two points of light, and the diameter of the halo and starbursts that surround a bright white point source. Methods 60 subjects (aged 18–65 years) were measured in a contralateral design where lens type was randomly assigned, one type to each eye. During activated testing, all visual measures of both study lenses were made while each eye was illuminated by a violet ( λ max = 365, half bandwidth 20 nm) activator, which caused steady-state activation of the photochromic lens during the period of testing. Two-point thresholds were determined by measuring the minimum distance between two points of broadband xenon light. Glare geometry was measured using an aperture (∼4 mm) that created a bright point source of light 45 inches from the plane of the eye. Between the point source and subject, a centering precision caliper was used to measure lateral spread of halos (diffusion around the source) and visual spokes. The head was stabilized using an adjustable head-rest assembly and the eye was aligned and monitored with a bore camera. Results Compared to the non-photochromic lens, and based on the stimulus conditions used in these measurements, the activated and inactivated photochromic lens reduced the light spread using the two-point threshold technique by 32% and 19% respectively; the diameter of the halos were reduced by 44% and 16% respectively; and the spokes were narrowed by 39% and 20% respectively. Based on 95% confidence interval testing, these effects were all statistically significant ( p < 0.05). Conclusions These results are consistent with previous data showing that soft contact lenses with a photochromic additive can improve many aspects of visual function, consistent with their level or activation. Our past data focused on visual function under bright light conditions (e.g., glare disability, discomfort, photostress recovery and chromatic contrast) with an activated photochromic. In this study, we found differences even in the inactivated state, using less intense stimuli (10 cd/m 2 at the source). This suggests that the photochromic lens improves the effects of light scatter even at lower luminance.

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“…Reduced lens curvatures and thicknesses are possible if high refractive index materials are used, 12 whereas lower refractive indices require higher lens curvatures, and for a given lens diameter this results in a thicker lens. To avoid excessive thickness, optic diameters with low refractive index materials can be reduced, 35 which can increase dysphotopsias produced by peripheral light sources. Also, the differences in polychromatic image quality generated by altering IOL Abbe number are likely to be much smaller than those generated by other defocus sources.…”

Section: Discussionmentioning

confidence: 99%

<p>The Impact of IOL Abbe Number on Polychromatic Image Quality of Pseudophakic Eyes</p>

Bradley

Wang³

et al. 2020

OPTH

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The human eye exhibits large amounts (2.5 diopters) of longitudinal chromatic aberration (LCA). Its impact on polychromatic image quality, however, has been shown experimentally and by computer modeling to be small or absent. We hypothesized that modest changes in pseudophakic LCA created by higher and lower Abbe number materials will have little or no impact on polychromatic image quality in pseudophakic eyes. Materials and Methods: Using published chromatic and monochromatic aberration data from pseudophakic eyes and higher and lower Abbe number materials (37 and 55), we computed monochromatic point spread functions for 21 wavelengths across the visible spectrum. After weighting by either the RGB spectra of a liquid crystal display or by a flat white spectrum, they were weighted by the human spectral sensitivity function (V λ) before being added to generate polychromatic PSFs. Results: In the absence of monochromatic aberrations, the reduced LCA due to higher Abbe number intraocular lens (IOL) materials resulted in a reduction of 0.08 diopters in the mean defocus generated by LCA. At the retinal plane, the higher Abbe number pseudophakic model produced improvements in polychromatic modulation transfer functions (MTFs) similar to those generated by a 0.05 diopter reduction in spherical defocus. When monochromatic aberrations were added to make the model more representative of actual pseudophakic eyes, the differences in image quality became sub-threshold for human vision or disappeared completely. Conclusion: The anticipated gains in polychromatic image quality from employing higher Abbe number IOL materials with reduced LCA do not materialize in plausible aberrated models of pseudophakic eyes.

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In vitro and schematic model eye assessment of glare or positive dysphotopsia-type photic phenomena: Comparison of a new material IOL to other monofocal IOLs

Cited by 26 publications

References 21 publications

Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

The effects of light scatter when using a photochromic vs. non-photochromic contact lens

<p>The Impact of IOL Abbe Number on Polychromatic Image Quality of Pseudophakic Eyes</p>

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