In-tube solid-phase microextraction based on NH 2 -MIL-53(Al)-polymer monolithic column for online coupling with high-performance liquid chromatography for directly sensitive analysis of estrogens in human urine

Luo, Xialin; Li, Gongke; Hu, Yufei

doi:10.1016/j.talanta.2016.12.050

Cited by 66 publications

(27 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As presented in Table , LODs of the developed method are comparable with that of in‐tube SPME‐HPLC‐DAD and SPME‐UPLC‐MS/MS , but inferior to other methods based on in‐tube SPME coupled with MS and fluorescence detector . Linear ranges are superior to in‐tube SPME‐LC‐MS/MS , and comparable with other methods . Regarding enrichment factors, the proposed method is better than these methods , demonstrating that hollow fibers have strong adsorption capacity for estrogens.…”

Section: Resultsmentioning

confidence: 76%

“…The proposed method was compared with some reported methods in terms of LODs, linear ranges, enrichment factors, extraction time, and repeatability . As presented in Table , LODs of the developed method are comparable with that of in‐tube SPME‐HPLC‐DAD and SPME‐UPLC‐MS/MS , but inferior to other methods based on in‐tube SPME coupled with MS and fluorescence detector .…”

Section: Resultsmentioning

confidence: 98%

See 1 more Smart Citation

Bare polyprolylene hollow fiber as extractive phase for in‐tube solid‐phase microextraction to determine estrogens in water samples

Sun

et al. 2019

J of Separation Science

View full text Add to dashboard Cite

Polypropylene hollow fibers as the adsorbent were directly filled into a polyetheretherketone tube for in-tube solid-phase microextraction. The surface properties of hollow fibers were characterized by a scanning electron microscope. Combined with high performance liquid chromatography, the extraction tube showed good extraction performance for five environmental estrogen hormones. To achieve high analytical sensitivity, four important factors containing sampling volume, sampling rate, content of organic solvent in sample, and desorption time were investigated. Under the optimum conditions, an online analysis method was established with wide linear range (0.03-20 μg/L), good correlation coefficients (≥0.9998), low limits of detection (0.01-0.05 μg/L), low limits of quantitation (0.03-0.16 μg/L), and high enrichment factors . Relative standard deviations (n = 3) for intraday (≤3.6%) and interday (≤5.1%) tests proved the stable extraction performance of the material. Durability and chemical stability of the extraction tube were also investigated, relative standard deviations of all analytes were less than 5.8% (n = 3), demonstrating the satisfactory stability. Finally, the method was successfully applied to detect estrogens in real samples. K E Y W O R D Sestrogen hormones, high performance liquid chromatography, online analysis, polyprolylene hollow fibers, solid-phase microextraction 2398

show abstract

Section: Resultsmentioning

confidence: 76%

Section: Resultsmentioning

confidence: 98%

Bare polyprolylene hollow fiber as extractive phase for in‐tube solid‐phase microextraction to determine estrogens in water samples

Sun

et al. 2019

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…MIL‐53‐NH 2 (Al) is frequently used for the extraction of different drugs and biomarkers from water and wastewater (An et al, ; Yusuf, Badjah‐Hadj‐Ahmed, Aqel, & ALOthman, ). Previous reports showed that MIL‐53‐NH 2 (Al) could be used for the extraction of estrogens from urine (Luo, Li, & Hu, ), polycyclic aromatic hydrocarbons (PAHs) from water and wastewater (Hu, He, Chen, Zhong, & Hu, ), nitrogenated compounds from liquid fuel (Abdelhameed, El‐Deib, El‐Dars, Ahmed, & Emam, ), arsenate from water (Li, Wu, Li, Zhu, & Li, ) and bisphenol from aqueous solutions (Zhou et al, ).…”

Section: Introductionmentioning

confidence: 99%

Determination of urinary methylhippuric acids using MIL‐53‐NH₂ (Al) metal–organic framework in microextraction by packed sorbent followed by HPLC–UV analysis

Pirmohammadi

Bahrami

Nematollahi

et al. 2019

Biomedical Chromatography

View full text Add to dashboard Cite

For the analysis of methylhippuric acids (MHAs) in human urine samples, in this study, a new method based on the metal–organic framework (MOF) of MIL‐53‐NH2 (Al) in microextraction by packed sorbent (MEPS) was developed. The synthesis of MIL‐53‐NH2 (Al) was characterized by Fourier transform infrared spectra, field emission‐scanning electron microscopy and X‐ray diffraction. Response surface methodology was used to investigate the influences of several parameters including type and volume of elution, type of conditional solvent, sample volume and extraction cycle on MEPS efficiency. The results showed good recoveries (>94%) and excellent extraction efficiencies (>96%) at three different concentrations of 50, 500 and 1500 μg ml−1 (as low, mid and high concentrations, respectively) of MHA isomers. Calibration curves of MHAs were linear over the concentration range of 1–1500 μg ml−1, with high correlation coefficients (r ≥ 0.998). The reproducibility of the proposed MIL‐53‐MEPS for determination of three isomers of MHA was found to be in the range of 3.5–11.1%. After optimization of the proposed technique, it was used to analyze MHAs in urine samples of workers exposed to xylenes in a petrochemical plant in Asalouyah, Iran. The results indicated that the MOF–MEPS method was selective, sensitive, rapid and efficient for the extraction of urinary MHAs. The technique is also environmentally friendly and inexpensive, and the MOF sorbent is reusable.

show abstract

Section: Introductionmentioning

confidence: 99%

“…[39][40][41][42][43] Estrogens have been extracted by cloud point, membrane assisted liquid-liquid extraction, solid phase extraction, and solid phase microextraction (SPME) [44][45][46][47] from water, silt, animal tissues, and aquatic products. 48 Stir bar, dispersive liquid-liquid microextraction, and ultrasound-assisted surfactant-enhanced emulsification microextraction have also been employed in extracting estrogen.49-51 Extraction of estrogen in infant milk powder by core-shell MIC has not been reported previously.In the present paper, spherical core-shell magnetic Fe 3 O 4 @SiO 2 @MIC with E2 as template was prepared through coating MIC on magnetic microparticles via cryogenical free radical polymerization. The prepared Fe 3 O 4 @SiO 2 @MIC was utilized in the selective extraction of E2 from infant formula milk powder.…”

mentioning

confidence: 99%

Preparation and Performance of an Estradiol Templated Magnetic Sphere of Molecularly Imprinted Cryogel

Wang¹,

Tian²,

Yan³

et al. 2017

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

An estradiol templated core-shell magnetic molecularly imprinted cryogel (MMIC) was synthesized to selectively extract and analyze estradiol in milk powder. The microsphere of Fe 3 O 4 @SiO 2 was firstly prepared on Fe 3 O 4 with ethyl silicate and 3-methyl propyl trimethoxy silane. Then the polymerization of α-methacrylic acid and ethylene glycol dimethyl acrylate was carried out on Fe 3 O 4 @SiO 2 at −20 °C for 24 h with estradiol as template. The morphology and microstructure of MMIC were investigated by transmission electron microscopy and infrared spectrogram. When used as chromatographic stationary phase, MMIC showed good selectivity and chromatographic performance for the template. Spiked milk powder samples were used to examine the adsorption capacity and selectivity of MMIC, giving recoveries of 92-101% and limit of detection 0.8-1.2 ng g −1 .Experimental results indicate good reproducibility with relative standard deviation from 2.2 to 4.5% (n = 3) at spiked levels of estradiol 10, 50, and 100 ng g -1 .Keywords: magnetic sphere, molecularly imprinted cryogel, estradiol, milk powder IntroductionSample preparation is of vital importance in an analysis for reducing the interference of impurities, concentrating the low abundant components, and improving the sensitivity and selectivity. Sample pretreatment occupies more than 60% of the entire time, while it presents poor reproducibility and accuracy. Thus, a sound sample pretreatment is crucial to guarantee the accuracy, reliability of the results, as well as the efficiency of analytical determination. Solid phase extraction (SPE) has widely been used in the extraction, purification, and enrichment of analytes in environmental, food, and biological samples. However, SPE cannot eliminate the interference of matrix in complex samples because the conventional adsorbents, such as normal, reverse, and ionic phase and other special adsorbents, have poor selectivity. Molecularly imprinted polymer (MIP) is a kind of inclusive compound prepared from template, monomer, and cross linker. There is a covalent bond or hydrogen bond or Van der Waals' force between template and polymer.2 When template molecule is removed, a specific cavity with binding sites complementary to the size, shape, and functional group of template is formed in the polymer.2 Molecularly imprinted polymers based solid phase extraction (MIP-SPE) can be implemented in selective separation, analysis, and preparation of high-purity target substance. MIP-SPE can achieve rapid and high efficiency of extraction of the analytes, because of high specific surface area and high mass transfer rate. 3,4Core-shell magnetic molecularly imprinted polymer (MMIP) is a new type of functional composite, the magnetic core (such as Fe 3 O 4 ) of which is covered with inorganic (SiO 2 , Al 2 O 3 , etc.) or organic (surfactant, polymer, etc.) layers. [5][6][7] The layer can be further modified with hydrophilic and/or biocompatible functional groups, including C=C, -NH-, -Br and sulfonyl, then dipole interaction of core is...

show abstract

In-tube solid-phase microextraction based on NH 2 -MIL-53(Al)-polymer monolithic column for online coupling with high-performance liquid chromatography for directly sensitive analysis of estrogens in human urine

Cited by 66 publications

References 30 publications

Bare polyprolylene hollow fiber as extractive phase for in‐tube solid‐phase microextraction to determine estrogens in water samples

Bare polyprolylene hollow fiber as extractive phase for in‐tube solid‐phase microextraction to determine estrogens in water samples

Determination of urinary methylhippuric acids using MIL‐53‐NH₂ (Al) metal–organic framework in microextraction by packed sorbent followed by HPLC–UV analysis

Preparation and Performance of an Estradiol Templated Magnetic Sphere of Molecularly Imprinted Cryogel

Contact Info

Product

Resources

About

In-tube solid-phase microextraction based on NH 2 -MIL-53(Al)-polymer monolithic column for online coupling with high-performance liquid chromatography for directly sensitive analysis of estrogens in human urine

Cited by 66 publications

References 30 publications

Bare polyprolylene hollow fiber as extractive phase for in‐tube solid‐phase microextraction to determine estrogens in water samples

Bare polyprolylene hollow fiber as extractive phase for in‐tube solid‐phase microextraction to determine estrogens in water samples

Determination of urinary methylhippuric acids using MIL‐53‐NH2 (Al) metal–organic framework in microextraction by packed sorbent followed by HPLC–UV analysis

Preparation and Performance of an Estradiol Templated Magnetic Sphere of Molecularly Imprinted Cryogel

Contact Info

Product

Resources

About

Determination of urinary methylhippuric acids using MIL‐53‐NH₂ (Al) metal–organic framework in microextraction by packed sorbent followed by HPLC–UV analysis