In-111 Pentetreotide Uptake in a Uterine Myoma

Mena, L.M.; Martı́n, Francisco; Jiménez, Ignacio; Ramos, Amadora

doi:10.1097/rlu.0b013e3181e06021

Cited by 5 publications

(6 citation statements)

References 8 publications

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“…Normal physiologic distribution of In-111 octreotide includes faint visualization of thyroid, pituitary gland and marked increased uptake in the liver, spleen, kidneys and bladder. Although rarely encountered, false-positive studies have been reported due to increased activity at nonmalignant pathologies such as Paget’s disease, parathyroid adenoma, cholecystitis, thrombus, abscess, infection, pulmonary fibrosis, pleural plaques and uterine myomas ( 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 ). Only a few cases in the literature have reported increased In-111 octreotide activity in the gallbladder ( 10 , 11 , 12 , 13 , 14 ).…”

Section: Literature Review and Discussionmentioning

confidence: 99%

Visualization of Gallbladder with In-111 Octreotide Scan

Özülker

Özülker²,

Tatoğlu³

et al. 2015

Mirt

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A 54-year-old woman underwent octreotide scintigraphy for evaluation of neuroendocrine tumor recurrence. The images demonstrated unusual uptake in gallbladder area in addition to physiologic uptake at other tissues. Whole-body planar and SPECT imaging were repeated after fatty meal ingestion at 28 hours in order to figure out whether this activity was physiologic or not. Since the unusual uptake in the gallbladder was still detected at these images, additional images were obtained 72 hours after radionuclide injection. The activity in the gallbladder disappeared at these images revealing the physiologic nature of this unusual accumulation.

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Section: Literature Review and Discussionmentioning

confidence: 99%

Visualization of Gallbladder with In-111 Octreotide Scan

Özülker

Özülker²,

Tatoğlu³

et al. 2015

Mirt

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“…Mena et al (9) reported an incidental 111 pentetreotide uptake in a partially calcified uterine myoma. In our case, a focal accumulation was presumably caused by the expression of somatostatin receptors on the inflammatory cells of the myoma.…”

Section: Discussionmentioning

confidence: 99%

An Incidentally Found Inflamed Uterine Myoma Causing Low Abdominal Pain, Using Tc-99m-Tektrotyd Single Photon Emission Computed Tomography-CT Hybrid Imaging

et al. 2013

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We report the case of a 50-year-old woman presented with a history of right hemicolectomy due to an ileocecal neuroendocrine tumor and left breast metastasis. Owing to a slightly elevated chromogranin A-level and lower abdominal pain, single photon emission computed tomography-computer tomography (SPECT-CT) was performed. There were no signs of recurrence on the SPECT-CT scan, but the patient was incidentally found to have an inflamed intramural myoma. We believe that the slightly elevated chromogranin A-level was caused by the hypertension that the patient presented. In the clinical context, this is a report of an inflamed uterine myoma seen as a false positive result detected by TC-99m-Tc-EDDA/HYNIC-Tyr3-Octreotide (Tektrotyd) SPECT-CT hybrid imaging.

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“…111 In-octreotide uptake around an intramural myoma that shows peripheral calcification on CT has been attributed to inflammatory processes (2). However, in a preliminary study, somatostatin receptor 2 and 5 gene expression and increased expression during pregnancy were found in leiomyoma (3), and in a small clinical trial, administration of lanreotide (a long-acting somatostatin analog) resulted in reduction of uterine and myoma volumes (4).…”

Section: Discussionmentioning

confidence: 99%

“…Uterine leiomyoma is the most common benign pelvic tumor in women (2,3). 111 In-octreotide uptake around an intramural myoma that shows peripheral calcification on CT has been attributed to inflammatory processes (2).…”

Section: Discussionmentioning

confidence: 99%

99mTc-Octreotide Uptake in the Uterus and a Subserosal Myoma Mimicking Tumoral Masses

Pirayesh

Amoui

Assadi

2014

Journal of Nuclear Medicine Technology

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The diagnostic usefulness of somatostatin receptor scintigraphy in the localization of tumors has been evaluated in several studies. Here, we present the case of a patient with a subserosal myoma diagnosed by 99m Tc-labeled octreotide acetate scintigraphy. Oval and ring-shaped areas of hyperactivity in the pelvis were confirmed on MR imaging to be the uterus and a subserosal myoma. The presented case indicates that somatostatin receptors may be present in the uterus and in leiomyomas, especially in young women, and demonstrates that somatostatin may be a promising therapy for treatment of myoma. The case also demonstrates that subserosal myoma or dislocation of the uterus can result in a false-positive diagnosis, highlighting the importance of correlative imaging for accurate interpretation of the study.

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In-111 Pentetreotide Uptake in a Uterine Myoma

Cited by 5 publications

References 8 publications

Visualization of Gallbladder with In-111 Octreotide Scan

Visualization of Gallbladder with In-111 Octreotide Scan

An Incidentally Found Inflamed Uterine Myoma Causing Low Abdominal Pain, Using Tc-99m-Tektrotyd Single Photon Emission Computed Tomography-CT Hybrid Imaging

99mTc-Octreotide Uptake in the Uterus and a Subserosal Myoma Mimicking Tumoral Masses

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