2012
DOI: 10.1586/erv.12.79
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Improving influenza vaccines

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Cited by 3 publications
(1 citation statement)
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“…Influenza virus continues to threaten global human health with significant morbidity and mortality. Induction of influenza virus-specific neutralizing antibodies (Abs) by vaccines is the most efficient strategy, because the neutralizing Abs can conjugate virus particles at the first contact of their invasion and promote clearance by host cells ( 1 , 2 ). To generate Abs with high affinity and pathogen-neutralization ability, naïve B cells are activated and divide in response to cognate antigen and subsequently undergo rounds of somatic hypermutation and selection ( 3 ).…”
Section: Introductionmentioning
confidence: 99%
“…Influenza virus continues to threaten global human health with significant morbidity and mortality. Induction of influenza virus-specific neutralizing antibodies (Abs) by vaccines is the most efficient strategy, because the neutralizing Abs can conjugate virus particles at the first contact of their invasion and promote clearance by host cells ( 1 , 2 ). To generate Abs with high affinity and pathogen-neutralization ability, naïve B cells are activated and divide in response to cognate antigen and subsequently undergo rounds of somatic hypermutation and selection ( 3 ).…”
Section: Introductionmentioning
confidence: 99%