Molecular Vaccines 2013
DOI: 10.1007/978-3-319-00978-0_26
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Influenza Cell-Culture Vaccine Production

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Cited by 4 publications
(2 citation statements)
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“…Baxter licensed in Europe Celvapan, a Vero cell-derived pandemic vaccine based on a wild-type "A/California/04/2009 (H1N1pdm09)"strain, in October 2009. 12,19 Preflucel, also manufactured by Baxter, is a seasonal influenza vaccine based on a Vero cell-line platform to produce three inactivated influenza viruses, including the A/H1N1 pandemic strain. During the 2008-2009 influenza season, a Phase III clinical study of Preflucel was conducted in the US.…”
Section: Cell Culture-derived Vaccinesmentioning
confidence: 99%
“…Baxter licensed in Europe Celvapan, a Vero cell-derived pandemic vaccine based on a wild-type "A/California/04/2009 (H1N1pdm09)"strain, in October 2009. 12,19 Preflucel, also manufactured by Baxter, is a seasonal influenza vaccine based on a Vero cell-line platform to produce three inactivated influenza viruses, including the A/H1N1 pandemic strain. During the 2008-2009 influenza season, a Phase III clinical study of Preflucel was conducted in the US.…”
Section: Cell Culture-derived Vaccinesmentioning
confidence: 99%
“…In contrast to egg-based production processes, cell-based production technology allows manufacturers to respond to market needs faster and in shorter production cycles and also allows a greater surge capacity, greater process control, and a more reliable and well-characterized product. Cell-based production allows manufacturers to supply higher quantities of the vaccines in a shorter amount of time [ 22 24 ]. Moreover, the virus obtained in cell cultures has a higher similarity with the circulating strains, in contrast with the virus produced in eggs, which might have antigenic modifications [ 25 27 ].…”
Section: Introductionmentioning
confidence: 99%