Improvement of antioxidant status after Brazil nut intake in hypertensive and dyslipidemic subjects

Huguenin, Grazielle Vilas Bôas; Oliveira, Gláucia Maria Moraes de; Moreira, Annie Seixas Bello; Saint’Pierre, Tatiana Dillenburg; Gonçalves, Ramiro; Pinheiro-Mulder, Alessandra R.; Teodoro, Anderson Junger; Luiz, Ronir Raggio; Rosa, Glorimar

doi:10.1186/s12937-015-0043-y

Cited by 53 publications

(64 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In physiological condition, endogenous generation of reactive oxygen species (ROS) could rapidly be detoxified by antioxidant enzymes including SOD and CAT. Walnut and Brazil nuts have been shown to contribute to a significant antioxidant effect in experimental rats and disease conditions, including hypertension [30][31][32]. Analysis of the effects of cashew nut in the diet on antioxidant status of human subjects with metabolic syndrome resulted in an increased antioxidant capacity [24].…”

Section: Discussionmentioning

confidence: 99%

Roasted Cashew Nut Kernel (Anacardium Occidentale L.) Supplementation Improves Hepatic and Renal Status but Not Lipid Profile in Rats

Famurewa¹,

Abi²,

Eru³

2016

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: Although studies suggest that nut consumption is associated with a variety of beneficial health outcomes, however, there is a dearth of datain the literature to document this effect for roasted cashew nut kernel (RCNK). Our objective was to determine whether dietary consumption of RCNKcould improve lipid profile, hepatic and renal status in rats.Methods: A total of 24 rats were randomly divided into four groups: A control and three experimental groups fed with roasted cashew nutsupplementeddietatdifferentconcentrationsfor28consecutivedays.Aftertheexperimentalperiod,ratswereanesthetized withether andretroorbitalbloodsampleswerewithdrawn.Serumsamples wereobtained toanalyzelipid profile,markersof oxidativestress,hepatic andrenalstatususingstandardmethods.Results: The supplemented diet significantly decreased the liver function parameters in rats. All the concentrations of RCNK in diets significantlyreduced serum creatinine and urea levels. However, total cholesterol and low-density lipoprotein-cholesterol (LDL-C) were significantly increased,whereas oxidative stress markers and malondialdehyde were improved by the supplemented diet, although insignificantly, as compared with thecontrol.Conclusions: These results suggest that RCNK may have beneficial health effects on the liver and kidney status although marked improvement wasnot demonstrated in oxidative stress markers. However, the significant increase in serum total and LDL-C indicates the need for further studies.Keywords: Roasted cashew nut, Anacardium occidentale, Lipid profile, Liver enzymes, Oxidative stress.

show abstract

Section: Discussionmentioning

confidence: 99%

Roasted Cashew Nut Kernel (Anacardium Occidentale L.) Supplementation Improves Hepatic and Renal Status but Not Lipid Profile in Rats

Famurewa¹,

Abi²,

Eru³

2016

Asian J Pharm Clin Res

View full text Add to dashboard Cite

show abstract

“…Nutrients show antioxidant activities, especially vitamin E and phenolic compounds [9], with nuts standing out as a source of both [10]. In vitro studies [11][12][13][14][15][16][17][18], animal models [19][20][21][22][23][24], observational studies [25], and randomized trials [26][27][28][29][30][31][32] suggest the potential benefit of including different nuts in the diet to improve biomarkers of oxidative stress.…”

Section: Introductionmentioning

confidence: 99%

Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease

Santos¹,

Quadros²,

Weschenfelder³

et al. 2020

Nutrients

View full text Add to dashboard Cite

Atherosclerosis is related to fat accumulation in the arterial walls and vascular stiffening, and results in acute coronary syndrome which is commonly associated with acute myocardial infarction. Oxidative stress participates in the pathogenesis of atherosclerosis. Thus, the inclusion of food sources of dietary antioxidants, such as different kinds of nuts, may improve biomarkers related to oxidative stress, contributing to a possible reduction in atherosclerosis progression. This article has briefly highlighted the interaction between oxidative stress, atherosclerosis, and cardiovascular disease, in addition to the effect of the consumption of different nuts and related dietary antioxidants—like polyphenols and vitamin E—on biomarkers of oxidative stress in primary and secondary cardiovascular prevention. Studies in vitro suggest that nuts may exert antioxidant effects by DNA repair mechanisms, lipid peroxidation prevention, modulation of the signaling pathways, and inhibition of the MAPK pathways through the suppression of NF-κB and activation of the Nrf2 pathways. Studies conducted in animal models showed the ability of dietary nuts in improving biomarkers of oxidative stress, such as oxLDL and GPx. However, clinical trials in humans have not been conclusive, especially with regards to the secondary prevention of cardiovascular disease.

show abstract

“…A comercialização das amêndoas representa atividade econômica basicamente extrativista. Devido aos altos teores de selênio encontrados nas amêndoas (Kluczkovski et al, 2015), 2/10 Costa MG, Tonini H, Mendes P Fo Floresta e Ambiente 2017; 24: e20150042 a castanha-do-brasil, como alimento, contribui na prevenção de doenças (Rayman, 2002;Huguenin et al, 2015) e o seu reconhecimento como alimento funcional aumenta o apelo para o seu consumo.…”

Section: Introdução E Objetivosunclassified

Atributos do Solo Relacionados com a Produção da Castanheira-do-Brasil (Bertholletia excelsa)

2017

View full text Add to dashboard Cite

RESUMONeste estudo foram analisados os atributos do solo relacionados com variações na produção de frutos da castanheira bem como o estado nutricional da espécie. As árvores foram selecionadas em parcela permanente (Caracaraí, RR) e divididas em quatro classes de produção: alta, média, baixa e muito baixa. Em novembro de 2009, amostras de solo e folhas foram coletadas para se avaliar a fertilidade do solo, o número de esporos de fungos micorrízicos arbusculares e o estado nutricional das árvores. Árvores com maior produção de frutos ocorreram associadas a maior teor de Al trocável na camada de 0-20 cm do solo, bem como a menor valor de pH e saturação por bases. A variável discriminante resultante deste estudo não foi considerada como responsável por interferir no potencial produtivo da castanheira-do-brasil, mas serviu como indicativo de que árvores mais produtivas contribuem na remoção de bases trocáveis, favorecendo a acidificação do solo.Palavras-chave: extrativismo, acidez do solo, absorção de bases, Roraima. Soil Attributes Related with Production of Brazil Nut Tree (Bertholletia excelsa) ABSTRACTIn this study we analyzed the soil attributes related with variation in the fruit production of Brazil nut trees, as well as the nutritional status of the species. Trees were selected in permanent plot (Caracaraí -RR) and divided in four production classes: High, Medium, Low and Very low. In November 2009, soil and leaves samples were taken to evaluate soil fertility, soil colonization by arbuscular mycorrhizal fungi, and trees nutritional status. Trees with higher fruits production occurred associated with higher exchangeable Al in soil depth of 0-20 cm, as well as to smaller pH and bases saturation values. The discriminant variable resulting of the present study was not assumed as responsible for interfering with the productive potential of Brazil nut trees; however, it indicates most productive trees contributing with exchangeable basis removal, favoring soil acidification.

show abstract

Improvement of antioxidant status after Brazil nut intake in hypertensive and dyslipidemic subjects

Cited by 53 publications

References 42 publications

Roasted Cashew Nut Kernel (Anacardium Occidentale L.) Supplementation Improves Hepatic and Renal Status but Not Lipid Profile in Rats

Roasted Cashew Nut Kernel (Anacardium Occidentale L.) Supplementation Improves Hepatic and Renal Status but Not Lipid Profile in Rats

Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease

Atributos do Solo Relacionados com a Produção da Castanheira-do-Brasil (Bertholletia excelsa)

Contact Info

Product

Resources

About