Improved Surgical Approach to Cardiac Tumors with Intraoperative Two-dimensional Echocardiography

Mora, Francisco; Mindich, Bruce P.; Guarino, Theresa; Goldman, Martin E.

doi:10.1378/chest.91.1.142

Cited by 9 publications

(1 citation statement)

References 15 publications

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“…Standard procedure Although total resection of cardiac sarcoma under intraoperative echocardiographic guidance during cardiopulmonary bypass may occasionally be feasible [37], most operations are palliative and are done to relieve cardiac compression or hemodynamic obstruction. Procedures may include simple biopsy, biopsy with subsequent pericardial window creation, or debulking.…”

Section: Surgical Excisionmentioning

confidence: 99%

Cardiac neoplasms

Rosenberg

Chan

Lichtenstein

et al. 1999

Curr Treat Options Cardio Med

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Surgical resection is usually the only form of curative therapy available for primary cardiac neoplasms. Benign tumors can often be completely removed with few complications and a low mortality rate, but complete resection is possible for fewer than half of primary malignant tumors. Radiation therapy plays an adjunct and palliative role in treatment. The outcome of chemotherapy, the dominant treatment method, is poor. Sarcomas are inherently chemoresistant and show a response rate of less than 50%. Lymphomas present late and respond poorly. Cardiectomy and cardiac transplantation may cure unresectable benign cardiac tumors or, rarely, malignant ones.

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Section: Surgical Excisionmentioning

confidence: 99%

Cardiac neoplasms

Rosenberg

Chan

Lichtenstein

et al. 1999

Curr Treat Options Cardio Med

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Primary cardiac angiosarcoma: A case report and review of therapeutic options

Stein

Deitling

Cantor

et al. 1994

Med. Pediatr. Oncol.

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A 45-year-old black patient presented with right-heart failure. Echocardiography showed a large tumor mass in the right atrium and a debulking procedure was performed. Histological and immunohistochemical studies revealed a high grade angiosarcoma infiltrating the myocardium and extending to the pericardial surface. Metastatic work-up showed no evidence of dissemination. The patient made an uneventful postsurgical recovery and was treated with chemotherapy, consisting of epidoxorubicin and dacarbazin. Following chemotherapy, echocardiographic re-evaluation failed to show any residual tumor in the right atrium. At present, one year following diagnosis, the patient is alive with no evidence of disease. Therapeutic options of primary cardiac angiosarcoma are reviewed.

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