Implants in dental and maxillofacial surgery

Abstract:The goal of the current publication is to provide a comprehensive literature review on the topic of dental implant materials. The following paper focuses on conventional titanium implants and more recently introduced and increasingly popular zirconia implants. Major subtopics include the material science and the clinical considerations involving both implant materials and the influence of their physical properties on the treatment outcome. Titanium remains the gold standard for the fabrication of oral implants, even though sensitivity does occur, though its clinical relevance is not yet clear. Zirconia implants may prove to be promising in the future; however, further in vitro and well-designed in vivo clinical studies are needed before such a recommendation can be made. Special considerations and technical experience are needed when dealing with zirconia implants to minimize the incidence of mechanical failure.

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“…Adopted from: Williams, 1981 [5]; Lemons, 1990 [6]; Craig, 1993 [7]; Sagomonyants et al , 2007 [8]; Berner et al , 2009 [9]. …”

Section: Introductionmentioning

confidence: 99%

A Critical Review of Dental Implant Materials with an Emphasis on Titanium versus Zirconia

2015

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“…Because proliferation of most mammalian cell types is anchoragedependent [4], the utilized scaffold must provide a suitable surface for cell attachment, proliferation, differentiation, and migration [5][6][7]. In addition, the scaffold material should be easy to handle and apply, while also being costeffective.…”

Section: Introductionmentioning

confidence: 99%

An in vivo study of the host tissue response to subcutaneous implantation of PLGA- and/or porcine small intestinal submucosa-based scaffolds

et al. 2007

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“…Ti(cpi) is one of the more corrosion resistant metals because of its outer passivating oxide layer, 1 which is a shared characteristic of Ti-6Al-4V. 2,3 Ti(cpi) is used to fabricate implants used in dentistry 4 and maxillofacial reconstruction, 5 as well as to coat devices constructed from titanium alloy. 6 Although Ti(cpi) is not strong enough to be used in orthopedics, 7 the addition of Al and V to Ti creates an alloy with great strength; and together with its low elastic modulus and excellent biocompatibility, 8 this makes it a preferred orthopedic material.…”

Section: Introductionmentioning

confidence: 99%

Titanium substrata composition influences osteoblastic phenotype:In vitro study

Zreiqat

Howlett

1999

J. Biomed. Mater. Res.

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In spite of observed differences at the interface between boon and either commercially pure titanium [Ti(cpi)] or titanium alloy (Ti-6Al-4V), the mechanism of such a response is ill understood. This prompted further investigation of the influence of similar metals on human bone-derived cells (HBDCs). This study investigated the influence of Ti(cpi) and its alloy on osteoblastic proteins formed by HBDCs grown for 5, 7, 10, and 14 days on these metals and compared them to cells grown on tissue culture polystyrene plates. Messenger RNA and translated proteins that form an array of osteogenic parameters were determined: alkaline phosphatase (ALP), thrombospondin, osteopontin, osteocalcin (OC), osteonectin (ON/SPARC), type I collagen (Col I) and bone sialoprotein (BSP). At the four predetermined time points, cells grown on either Ti(cpi) or Ti-6Al-4V generally expressed similar mRNA levels, while levels of their respective proteins differed. Cells on Ti(cpi) had peak levels for most proteins at day 7, whereas those on Ti-6Al-4V peaked at either day 5 and/or day 7. At day 5 cells grown on Ti-6Al-4V had higher levels of ALP, Col I, ON/SPARC, OC, and BSP than those in Ti(cpi); this difference was not maintained at later time points in culture. The differential regulation of proteins occurring between cells from the same patient grown on titanium and its alloy implies that HBDCs respond to small differences in the surface chemistry and/or microcrystallinity.

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Implants in dental and maxillofacial surgery

Cited by 57 publications

References 97 publications

A Critical Review of Dental Implant Materials with an Emphasis on Titanium versus Zirconia

A Critical Review of Dental Implant Materials with an Emphasis on Titanium versus Zirconia

An in vivo study of the host tissue response to subcutaneous implantation of PLGA- and/or porcine small intestinal submucosa-based scaffolds

Titanium substrata composition influences osteoblastic phenotype:In vitro study

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