Impacto da atenção farmacêutica no uso racional de antimicrobianos em uma unidade básica de saúde no interior do Estado de São Paulo

Neto, Paulo Roque Obreli; Vieira, Jessika Caroline; Cuman, Roberto Kenji Nakamura

doi:10.4025/actascihealthsci.v33i2.8006

Cited by 3 publications

(3 citation statements)

References 21 publications

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“…Not having internet access and information systems isolates pharmaceutical services compared to other health services, hindering the development of the therapeutic project, as well as consultations to literature, guidelines, and medical records that support the performed services. The service must be properly structured to contribute to the solutions of the care process, as pointed out by a study 20 on the use of computerized system and adoption of protocols for antimicrobial dispensing in the primary health care of the city of Salto Grande, São Paulo, which resulted in the decrease in the prescription and irrational use of these medicines.…”

Section: Discussionmentioning

confidence: 99%

Infrastructure of pharmacies of the primary health care in the Brazilian Unified Health System:

et al. 2017

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OBJECTIVE To characterize the infrastructure of the primary health care pharmacies of the Brazilian Unified Health System, aiming at humanizing the offered services.METHODS This is a cross-sectional study, of quantitative approach, from data obtained in the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos – Serviços, 2015 (PNAUM – National Survey on Access, Use and Promotion of Rational Use of Medicines – Services, 2015). Information on 1,175 pharmacies/dispensing units were gathered from direct observation and assessment of dispensing units installations conducted by trained researchers who used a standardized form. The analyzed variables refer to the physical structure of pharmacies or medicine dispensing units of the health units under research.RESULTS The pharmacy area was greater than 14 m2 in 40.3% of the sampled units, highlighting those from Midwest (56.9%) and Southeast (56.2%) regions and those of Northeast, with only 23.3%. About 80.2% units had waiting rooms with chairs for patients, 31.8% of them had dispensing areas inferior to 5m2, while in 46.2% these areas were superior to 10m2. Bars were found in service counters in 23.8% of health units, thus separating the patient from the professional; 44.1% had internet access. In most units, the area of medicine storage had no refrigerator or freezer for their exclusive storage and 13.7% had a specific room for pharmaceutical consultation.CONCLUSION Aiming at achieving care humanization and improving working conditions for professionals, the structuring of the environment of pharmacy services is necessary. This would contribute to the better qualification of pharmacy services, comprising more than medicine delivery. Data on the Northeast region indicated less favorable conditions to the development of adequate dispensing services. Based on the panorama pointed out, we suggest the expansion of stimulus concerning the physical structure of pharmaceutical services, considering regional specificities.

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Section: Discussionmentioning

confidence: 99%

Infrastructure of pharmacies of the primary health care in the Brazilian Unified Health System:

et al. 2017

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“…Alguns métodos podem ser utilizados para avaliar e controlar o avanço da resistência bacteriana como: 1 -a caracterização do perfil de prescrição dos antibacterianos, principal foco deste estudo; 2 -a elaboração de protocolos terapêuticos para processos infecciosos diversos; 3 -o treinamento e a formação dos prescritores; 4 -a conscientização da população sobre os riscos do uso abusivo de antibacterianos; 5 -a correta higienização das mãos; 6 -o monitoramento de pacientes infectados por bactérias multirresistentes; 7 -a atuação efetiva do farmacêutico clínico no controle da prescrição e dispensação de antibacterianos (3,4,24).…”

Section: Resultsunclassified

“…Uma revisão sistemática, que avaliou as intervenções para facilitar a tomada de decisão médica compartilhada para abordar o uso de antibacterianos em infecções agudas do sistema respiratório na atenção primária, destaca a decisão compartilhada oferecendo oportunidade de redução da prescrição de antibacterianos e melhora no uso racional (24).…”

Section: Resultsunclassified

Prescrições De Antibacterianos Em Uma Drogaria Do Município De Tanabi, São Paulo, Brasil

Lima

Silva

Pereira

et al. 2017

Infarma

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Antimicrobial drugs are substances able to prevent the proliferation or death of infectious agents, combating and preventing the dissemination of an infection. The abusive or inappropriate use of these drugs leads to the development of strains of multi-resistant microrganisms. The aim of this study was to describe the antimicrobial drug consumption in a drugstore at Tanabi, São Paulo, Brazil. This is a retrospective, descriptive, exploratory study with a quantitative approach. There were analyzed 128 prescriptions containing antimicrobial drugs dispensed in 2016. 64% of the prescriptions were destined to the female gender. The average age was 46 ± 25 years. The most prescribed antimicrobials were cephalexin (23%), amoxicillin associated with clavulanate (22%), ciprofloxacin (17%) and azithromycin (15%). Consequently, the most commonly used pharmacological groups were beta-lactams (55%), fluoroquinolones (30%) and macrolides (15%), respectively. The most frequent prescribers were general phisicians (42%), dentist (12%), cardiologist (9%) and urologist (7%). Most of the prescriptions came from the private health system (54%). The prescribers used the trade name in 55% of the prescribed antimicrobials, of which 33% were destined to the public health system. This research contributes to evaluation of the use of antimicrobial drugs in population. The effective action of the Pharmacist in the control the use of antibacterials in accordance with current legislation is important to provide the population with adequate guidelines on the rational use of these agents.

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Avaliação Da Prevalência Da Dispensação De Antimicrobianos Na Farmácia Pública Do Município De Cruz Alta –Rs

Deuschle

Marques³

2015

Rev. Eletr. Farm.

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____________________________________________________________________________ Resumo: Peptídeos antimicrobianos (PAMs) encontrados naturalmente em organismos vivos são uma grande promessa para o combate a doenças infecciosas, especialmente provocadas por micro-organismos multirresistentes aos antibióticos comerciais disponíveis no mercado, devido à intensa e inadequada aplicação dessas substâncias. No entanto, algumas características particulares que podem estar presentes em PAMs (tamanho grande, baixa solubilidade, existência de carga efetiva, elevada complexidade estrutural, etc.) representam dificuldade no uso desta classe de substâncias para aplicação clínica. Como uma abordagem para resolver esta barreira técnica para aplicação dos PAMs, diferentes formulações de lipossomas LUV foram preparadas com a intenção de promover a encapsulação de CcdBET2, um PAM com ação comprovada, e promover a sua entrega no ambiente intracelular. CcdBET2 foi sintetizado por metodologia de fase sólida e os lipossomas de 100 nm de diâmetro por extrusão. Os sistemas peptídeo-lipossomas foram testados contra Staphylococcus aureus por uma metodologia quantitativa utilizando MTT para testar a sua capacidade em promover a interrupção do crescimento celular. É possível sugerir que o sistema lipossomal é responsável por interagir com a membrana bacteriana permitindo que CcdBET2 exerça sua atividade antimicrobiana. Palavras-chave: Peptídeos antimicrobianos, lipossomas LUV, Staphylococcus aureus ____________________________________________________________________________ Abstract: Antimicrobial peptides (PAMs) found naturally in living organisms are a great promise for the fight against infectious diseases specially by microorganisms multiresistant to the commercial antibiotics available on the market due to intensive and inadequate applying of those substances. However, some particular characteristics that may be present in PAMs (big size, low solubility, the existence of effective load, high structural complexity, etc.) pose difficulty vis-à-vis the use of this class of substances for clinical application. As an approach to solve this technical barrier to application of PAMs, different formulations of LUV liposomes were prepared with the intent to promote the encapsulation of CcdBET2, a proven PAM, and promote its delivery in the intracellular environment. CcdBET2 was synthesized by solid-phase methodology and the 100 nm liposomes by extrusion. The peptide-liposomes systems were tested against Staphylococcus aureus by a quantitative methodology using MTT to test their ability in promote the interruption of cell growth. It is possible

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Impacto da atenção farmacêutica no uso racional de antimicrobianos em uma unidade básica de saúde no interior do Estado de São Paulo

Cited by 3 publications

References 21 publications

Infrastructure of pharmacies of the primary health care in the Brazilian Unified Health System:

Infrastructure of pharmacies of the primary health care in the Brazilian Unified Health System:

Prescrições De Antibacterianos Em Uma Drogaria Do Município De Tanabi, São Paulo, Brasil

Avaliação Da Prevalência Da Dispensação De Antimicrobianos Na Farmácia Pública Do Município De Cruz Alta –Rs

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