Impact of obstructive sleep apnea on blood pressure and cardiovascular risk factors in Japanese men: A cross-sectional study in work-site group

Morinaga, Yuki; Matsumura, Kiyoshi; Kansui, Yasuo; Sakata, Satoko; Gotō, Kenichi; Haga, Yoshie; Oishi, Emi; Seki, Takunori; Ohtsubo, Toshio; Kitazono, Takanari

doi:10.1080/10641963.2017.1324476

Cited by 6 publications

(5 citation statements)

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“…Another cross-sectional study involving 2740 adults in Korea [ 50 ] identified the “high risk” individuals as being older aged and having a BMI ≥ 25 kg/m 2 for OSA. Several other studies that involved large samples included a cross-sectional study ( n = 2208) in Japan addressing the association between hypertension and OSA [ 42 ], a multicenter study ( n = 1877) in Europe looking for the effects of OSA severity and other comorbidities on sleep pattern [ 51 ], a prospective cohort study ( n = 1825) in Korea determining the association between hypertension with OSA in patients with high levels of homocysteine in the blood [ 36 ], and a cross-sectional study ( n = 1272) in Belgium determining the prevalence of hypertension with insomnia [ 32 ].…”

Section: Resultsmentioning

confidence: 99%

“… Score = 4; high; study design, sample size, sample selection and data analyses, each scored 1. Morinaga et al, 2018 [ 42 ] Japan Cross-sectional study 2208 men (mean age, 44.4 ± 0.2 years) Hypertension The prevalence of mild-to-moderate (AHI of 5–29) and severe (AHI ≥ 30) OSA in the studied subjects were 7.1%, and 6.1%, respectively. Associations between hypertension and OSA were observed after adjustments for age, body mass index (BMI), estimated glomerular filtration rate, current alcohol intake, current smoking habits, and OSA treatment.…”

Section: Methodsmentioning

confidence: 99%

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Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

2021

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Obstructive sleep apnea (OSA) is a serious, potentially life-threatening condition. Epidemiologic studies show that sleep apnea increases cardiovascular diseases risk factors including hypertension, obesity, and diabetes mellitus. OSA is also responsible for serious illnesses such as congestive heart failure, stroke, arrhythmias, and bronchial asthma. The aim of this systematic review is to evaluate evidence for the association between OSA and cardiovascular disease morbidities and identify risk factors for the conditions. In a review of 34 studies conducted in 28 countries with a sample of 37,599 people, several comorbidities were identified in patients with severe OSA—these were: heart disease, stroke, kidney disease, asthma, COPD, acute heart failure, chronic heart failure, hyperlipidemia, thyroid disease, cerebral infarct or embolism, myocardial infarction, and psychological comorbidities including stress and depression. Important risk factors contributing to OSA included: age > 35 years; BMI ≥ 25 kg/m2; alcoholism; higher Epworth sleepiness scale (ESS); mean apnea duration; oxygen desaturation index (ODI); and nocturnal oxygen desaturation (NOD). Severe OSA (AHI ≥ 30) was significantly associated with excessive daytime sleepiness and oxygen desaturation index. The risk of OSA and associated disease morbidities can be reduced by controlling overweight/obesity, alcoholism, smoking, hypertension, diabetes mellitus, and hyperlipidemia.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

2021

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“…In a Japanese study, 2208 males were enrolled, similar to our situation where males predominated. In that study, the prevalence rates of mild-to-moderate (5 ≤ AHI < 30) and severe (AHI ≥ 30) OSA were 7.1 and 6.1%, respectively [ 16 ]. Although the number of recruited males outnumbered that of females, similar to our study, the Japanese prevalence rate was higher.…”

Section: Discussionmentioning

confidence: 99%

“…In a Japanese study of 2208 males, the prevalence of severe (apnea-hypopnea index (AHI) ≥30) OSA in the studied subjects was 6.1%. Both systolic and diastolic blood pressures were significantly increased in subjects with severe OSA compared with those without OSA [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Prospective study of the prevalence and co-morbidities of obstructive sleep apnea in active-duty army personnel in the three southernmost provinces of Thailand using questionnaire screening

Pilakasiri

Mahakit

2018

Military Med Res

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BackgroundIt is crucial for the army to know the prevalence of obstructive sleep apnea (OSA) syndrome in active-duty army personnel. Little information has been reported on the prevalence of OSA and clinical features in active-duty army personnel. This study was aimed to estimate the prevalence of snoring and risk of developing OSA in active-duty army personnel in Thailand and to identify the co-morbidities of OSA. In total, 1107 participants who were aged 20–60 years and were deployed to the three southernmost provinces of Thailand were enrolled. All the participants completed the Phramongkutklao (PMK) Hospital OSA Questionnaire that was modified and validated from the Berlin Questionnaire and underwent physical examination. The participants were 1107 active-duty army personnel in the three southernmost provinces of Thailand, both males and females, aged 20–60 years.MethodsThe PMK OSA Questionnaire was used to assess the risk of OSA together with interviewing for snoring, fatigue, falling asleep and day-time sleepiness. Physical examination of the neck, chest and hip circumference, and height was performed. Information concerning physical training, co-morbid diseases, smoking and alcoholic consumption was collected.ResultsThe prevalence of snoring was 58.5, and 4.8% met the PMK OSA Questionnaire criteria, thus indicating a high risk of OSA. The information obtained indicated that laryngopharyngeal reflux (LPR), current smoking and alcoholic consumption were significantly higher in the high-risk OSA group.ConclusionEarly detection and treatment of OSA in active-duty army personnel are imperative. Physical examination and polysomnography can be used to reveal the high-risk group. High body mess index (BMI), laryngopharyngeal reflux, current smoking and alcoholic consumption are modifiable factors for OSA and are avoidable. A policy to decrease the BMI and risk of LPR, as well as to stop smoking and alcoholic consumption, should be applied.

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“…1,2 The main symptoms that can occur in OSAS patients are loud snoring and excessive daytime sleepiness so it can disrupt the quality of life and performance. 1,3 Some risk factors that can cause OSAS are obesity, age, neck circumference, and anatomic airway abnormalities. 4,5 OSAS is associated with metabolic and cardiovascular disorders such as diabetes mellitus, hypertension, congestive heart failure, and stroke.…”

Section: Introductionmentioning

confidence: 99%

The Correlation of Allergic Rhinitis with Obstructive Sleep Apnea Syndrome (OSAS) in Young Adults

Sianturi

Marliyawati

Yusmawan

et al. 2020

Diponegoro. Int. Med. J.

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Background: Obstructive Sleep Apnea Syndrome (OSAS) is a breathing disorder during sleep that can cause stopping breathing and trigger dangerous diseases. The main symptoms that can occur in OSAS patients are loud snoring and excessive daytime sleepiness so it can disrupt the quality of life and performance. Allergic rhinitis (AR) is one of the risk factors for OSAS, after age, obesity, sex, neck circumference, and anatomic abnormalities of the airway. Allergic rhinitis can disrupt the quality of sleep patients. Allergic rhinitis patient has a risk of OSAS due to obstruction of the upper airways so airflow to the lungs is obstructed.Objective: To analyze the relationship of allergic rhinitis with the incidence of Obstructive Sleep Apnea Syndrome (OSAS) in young adults.Methods: This study is an observational study with a cross-sectional design. Samples were obtained with a probability sampling method by consecutive sampling. The subject of this study were students of the Faculty of Medicine, Diponegoro University, aged 18-23 years. This study consisted of interviews, BMI examination, neck circumference examination, nose, and throat examination, fill the Epworth Sleepiness Scale (ESS) questionnaire to assess OSAS and the Score For Allergic Rhinitis (SFAR) questionnaire to assess allergic rhinitis. Statistical tests use chi-square, fisher's exact test, and logistic regression.Results: The incidence of allergic rhinitis with OSAS in young adults occurred as much as 79,7%. Bivariate analyze showed allergic rhinitis associated significantly with the incidence of OSAS in young adults (p=0,000; PR=12,3). The most common group of allergic rhinitis symptoms in allergic rhinitis patients with OSAS is the group of symptoms of sneezing, rhinorrhea, and nasal congestion.Conclusion: Allergic rhinitis patients risk 12,3 times more likely to suffer from OSAS than non-allergic rhinitis in young adults.Keyword: Allergic Rhinitis, OSAS, Young Adults

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Impact of obstructive sleep apnea on blood pressure and cardiovascular risk factors in Japanese men: A cross-sectional study in work-site group

Cited by 6 publications

References 28 publications

Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

Prospective study of the prevalence and co-morbidities of obstructive sleep apnea in active-duty army personnel in the three southernmost provinces of Thailand using questionnaire screening

The Correlation of Allergic Rhinitis with Obstructive Sleep Apnea Syndrome (OSAS) in Young Adults

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